Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shinta Kobayashi"'
Autor:
Evan Vosburgh, Yi-Chieh Nancy Du, Tanupriya Contractor, Shinta Kobayashi, Laura H. Tang, Chris R. Harris, Richard Clausen
Publikováno v:
Oncogenesis, Vol 8, Iss 3, Pp 1-13 (2019)
Oncogenesis
Oncogenesis
The two most common types of pancreatic neuroendocrine tumors (PanNETs) are insulinomas and nonfunctioning PanNETs (NF-PanNETs). Insulinomas are small, rarely metastatic tumors that secrete high amounts of insulin, and nonfunctioning PanNETs are larg
Autor:
Shinta Kobayashi, Laura H. Tang, Evan Vosburgh, Richard Clausen, Arnold J. Levine, Chang S. Chan, Tanupriya Contractor, Chris R. Harris, Edaise M da Silva
Publikováno v:
Oncotarget
In a mouse model for neuroendocrine tumors of the pancreas (PanNETs), liver metastasis occurred at a higher frequency in males. Male mice also had higher serum and intratumoral levels of the innate immunity protein complement C5. In mice that lost th
Publikováno v:
Cancer Research. 77:2260-2260
Neuroendocrine tumors are the most common tumors of the small intestine. Very little is known about genetic changes that cause SI-NETs, which have a very low frequency of mutations. SI-NETs are highly metastatic to the liver, and patients with liver
Publikováno v:
Experimental Cell Research. 313:1675-1686
Dynamin-like protein 1 (DLP1) and Pex11p{beta} function in morphogenesis of peroxisomes. In the present work, we investigated whether Fis1 is involved in fission of peroxisomes. Endogenous Fis1 was morphologically detected in peroxisomes as well as m
Publikováno v:
Experimental Cell Research. 312:1671-1684
We earlier isolated a Chinese hamster ovary cell line ZP121 showing morphologically abnormal, tubular peroxisomes, and apparent dysmorphogenesis of mitochondria. Here, we identified an inactivating point-mutation in dynamin-like protein 1 gene, DLP1,
Autor:
Tanupriya Contractor, Shinta Kobayashi, Edaise M da Silva, Laura H. Tang, Chang S. Chan, Richard Clausen, Chris R. Harris
Publikováno v:
Cancer Research. 76:478-478
Pancreatic neuroendocrine tumors are generally classified as functioning or nonfunctioning. Patients with functioning tumors can have severe hypoglycemia because their tumors express high amounts of insulin as well as chromogranin A; fortunately, the
Autor:
Arnold J. Levine, Edaise M da Silva, Evan Vosburgh, Laura H. Tang, Chang S. Chan, Yvonne Sun, Shinta Kobayashi, Chris R. Harris, Tanupriya Contractor, Richard Clausen
Publikováno v:
Cancer Research. 75:3185-3185
Among patients with neuroendocrine tumors, males are more likely than females to develop liver metastatic disease. We show that this male bias toward liver metastasis is also observed in a mouse model for pancreatic neuroendocrine tumorigenesis (PanN
Autor:
Masami Suzuki, Hironori Mutoh, Kenji Yoshida, Yu Jau Chen, Takashi Yoshikubo, Shinichi Funahashi, Shinta Kobayashi, Arnold J. Levine, Atsuhiko Kato, Hisafumi Yamada-Okabe, Takahiro Ochiya, Osamu Natori, Norikazu Tamaoki, Takeshi Watanabe, Yamazaki Tatsumi, Chie Kato, Masahiko Kuroda, Eri Hashimoto, Masaki Yamazaki, Motooki Ashihara, Koichi Matsubara, Yoshinori Watanabe
Publikováno v:
Stem cells (Dayton, Ohio). 30(12)
The cancer stem cell (CSC) concept has been proposed as an attractive theory to explain cancer development, and CSCs themselves have been considered as targets for the development of diagnostics and therapeutics. However, many unanswered questions co
Autor:
Kobayashi, Shinta1 (AUTHOR), Contractor, Tanupriya2 (AUTHOR), Vosburgh, Evan2 (AUTHOR), Du, Yi-Chieh Nancy3 (AUTHOR), Tang, Laura H.4 (AUTHOR), Clausen, Richard2 (AUTHOR), Harris, Chris R.2,5,6 (AUTHOR) harrisch@ca.rutgers.edu
Publikováno v:
Oncogenesis. Mar2019, Vol. 8 Issue 3, p1-18. 18p.
Autor:
Kobayashi, Shinta, Yamada-Okabe, Hisafumi, Suzuki, Masami, Natori, Osamu, Kato, Atsuhiko, Matsubara, Koichi, Jau Chen, Yu, Yamazaki, Masaki, Funahashi, Shinichi, Yoshida, Kenji, Hashimoto, Eri, Watanabe, Yoshinori, Mutoh, Hironori, Ashihara, Motooki, Kato, Chie, Watanabe, Takeshi, Yoshikubo, Takashi, Tamaoki, Norikazu, Ochiya, Takahiro, Kuroda, Masahiko
Publikováno v:
Stem Cells; Dec2012, Vol. 30 Issue 12, p2631-2644, 14p