Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Shinsuke Yokouchi"'
Autor:
Yoshiji Takemoto, Chihiro Tsukano, Takuma Yoshida, Shinsuke Yokouchi, Yusuke Kobayashi, Hugh Nakamura, Masayuki Igarashi, Motohiro Yasui
Publikováno v:
Journal of the American Chemical Society. 141:8527-8540
The first total synthesis of caprazamycin A (1), a representative liponucleoside antibiotic, is described. Diastereoselective aldol reactions of aldehydes 12 and 25–27, derived from uridine, with diethyl isocyanomalonate 13 and phenylcarbamate 21 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d5d0a79550e040d0e911eeb2af8dec
https://doi.org/10.1021/jacs.9b02220
https://doi.org/10.1021/jacs.9b02220
Autor:
Masayuki Igarashi, Hugh Nakamura, Chihiro Tsukano, Motohiro Yasui, Yoshiji Takemoto, Shinsuke Yokouchi
Publikováno v:
Angewandte Chemie. 127:3179-3182
Caprazamycin A has significant antibacterial activity against Mycobacterium tuberculosis (TB). The first total synthesis is herein reported and features a) the scalable preparation of the syn-β-hydroxy amino acid with a thiourea-catalyzed diastereos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ea0de526abfe8f043475ac71da0023
https://doi.org/10.1002/ange.201411954
https://doi.org/10.1002/ange.201411954
Autor:
Yoshiji Takemoto, Toshifumi Kuribayashi, Taro Enomoto, Shota Sakamoto, Shinsuke Yokouchi, Chihiro Tsukano, Anne-Lise Girard
Publikováno v:
ChemInform. 44
The Pt-catalyzed cyclization of various internal alkynylamides provides access towards diazepines with excellent 7-endo selectivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c663af148caecebb6ffb8e4c5d2e31e4
https://doi.org/10.1002/chin.201302158
https://doi.org/10.1002/chin.201302158
Autor:
Chihiro Tsukano, Shota Sakamoto, Shinsuke Yokouchi, Yoshiji Takemoto, Toshifumi Kuribayashi, Taro Enomoto, Anne-Lise Girard
Publikováno v:
Organicbiomolecular chemistry. 10(30)
The scope and limitations of the platinum catalyzed 7-endo cyclization of internal alkynyl amides were investigated. Substitution of the alkyne with an aryl group gave better results, presumably because it stabilized the transition state. Applying th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1bff32d0b4425a7372b7bfb83893f7
https://pubmed.ncbi.nlm.nih.gov/22508008
https://pubmed.ncbi.nlm.nih.gov/22508008
Publikováno v:
ChemInform. 42
In the presence of Bi(O-Tf)3 alkynylamides of type (I) are found to undergo 6-exo cyclization to afford piperazinones like (II).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e512d499218ecd22fee21b25c3cb3ee
https://doi.org/10.1002/chin.201141026
https://doi.org/10.1002/chin.201141026
Publikováno v:
Chemistry, an Asian journal. 6(6)
In the presence of Bi(O-Tf)3 alkynylamides of type (I) are found to undergo 6-exo cyclization to afford piperazinones like (II).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814e8061532ca77158e8396b914c8938
https://pubmed.ncbi.nlm.nih.gov/21548132
https://pubmed.ncbi.nlm.nih.gov/21548132