Zobrazeno 1 - 10
of 242
pro vyhledávání: '"Shinsuke Shibata"'
Autor:
Yusuke Kinashi, Keisuke Tanaka, Shunsuke Kimura, Masato Hirota, Seiga Komiyama, Tomoko Shindo, Akinori Hashiguchi, Daisuke Takahashi, Shinsuke Shibata, Shin-Ichiro Karaki, Hiroshi Ohno, Koji Hase
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105256- (2024)
Summary: Background: Intestinal epithelial cells (IECs) serve as robust barriers against potentially hostile luminal antigens and commensal microbiota. Epithelial barrier dysfunction enhances intestinal permeability, leading to leaky gut syndrome (LG
Externí odkaz:
https://doaj.org/article/8ccf4f716dee42168b9fba259ad46b8a
Autor:
Takayuki Nishijima, Kentaro Okuyama, Shinsuke Shibata, Hiroo Kimura, Munehisa Shinozaki, Takehito Ouchi, Yo Mabuchi, Tatsukuni Ohno, Junpei Nakayama, Manabu Hayatsu, Keiko Uchiyama, Tomoko Shindo, Eri Niiyama, Sayaka Toita, Jiro Kawada, Takuji Iwamoto, Masaya Nakamura, Hideyuki Okano, Narihito Nagoshi
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-20 (2024)
Abstract Background Severe peripheral nerve damage always requires surgical treatment. Autologous nerve transplantation is a standard treatment, but it is not sufficient due to length limitations and extended surgical time. Even with the available ar
Externí odkaz:
https://doaj.org/article/86440490ff964447b6e85a0598b21320
Autor:
Sopak Supakul, Rei Murakami, Chisato Oyama, Tomoko Shindo, Yuki Hatakeyama, Maika Itsuno, Hiroko Bannai, Shinsuke Shibata, Sumihiro Maeda, Hideyuki Okano
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-21 (2024)
Abstract Background The development of induced pluripotent stem cells (iPSCs) technology has enabled human cellular disease modeling for inaccessible cell types, such as neural cells in the brain. However, many of the iPSC-derived disease models esta
Externí odkaz:
https://doaj.org/article/40cba472ec6b49c09723aa64390eeb24
Autor:
Yu Suematsu, Narihito Nagoshi, Munehisa Shinozaki, Yoshitaka Kase, Yusuke Saijo, Shogo Hashimoto, Takahiro Shibata, Keita Kajikawa, Yasuhiro Kamata, Masahiro Ozaki, Kaori Yasutake, Tomoko Shindo, Shinsuke Shibata, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-17 (2023)
Abstract Background Human induced pluripotent stem cell-derived neural stem/progenitor cell (hiPSC-NS/PC)-based cell transplantation has emerged as a groundbreaking method for replacing damaged neural cells and stimulating functional recovery, but it
Externí odkaz:
https://doaj.org/article/3e108cd040a0415693c9639aef17b23a
Autor:
Jitrapa Pinyomahakul, Masataka Ise, Meiko Kawamura, Takashi Yamada, Kentaro Okuyama, Shinsuke Shibata, Jun Takizawa, Manabu Abe, Kenji Sakimura, Hirohide Takebayashi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7776 (2024)
The Vps13a gene encodes a lipid transfer protein called VPS13A, or chorein, associated with mitochondria-associated endoplasmic reticulum (ER) membranes (MAMs), mitochondria–endosomes, and lipid droplets. This protein plays a crucial role in inter-
Externí odkaz:
https://doaj.org/article/daa25f44929c46f3a51ae6e412c707e7
Autor:
Hiroaki Takeya, Shun Itai, Hiroo Kimura, Yuta Kurashina, Tsuyoshi Amemiya, Narihito Nagoshi, Takuji Iwamoto, Kazuki Sato, Shinsuke Shibata, Morio Matsumoto, Hiroaki Onoe, Masaya Nakamura
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Chitosan has various tissue regeneration effects. This study was designed to investigate the nerve regeneration effect of Schwann cell (SC)-encapsulated chitosan-collagen hydrogel nerve conduit (CCN) transplanted into a rat model of sciatic
Externí odkaz:
https://doaj.org/article/f48487bf87de4bb79a4f9495fda5fc32
Autor:
Syoichi Tashiro, Shinsuke Shibata, Narihito Nagoshi, Liang Zhang, Shin Yamada, Tetsuya Tsuji, Masaya Nakamura, Hideyuki Okano
Publikováno v:
Cells, Vol 13, Iss 5, p 412 (2024)
There is no choice other than rehabilitation as a practical medical treatment to restore impairments or improve activities after acute treatment in people with spinal cord injury (SCI); however, the effect is unremarkable. Therefore, researchers have
Externí odkaz:
https://doaj.org/article/2efa34599e2843f0ad78054900ca2003
Autor:
Satoko Umeda, Tomohisa Sujino, Kentaro Miyamoto, Yusuke Yoshimatsu, Yosuke Harada, Keita Nishiyama, Yoshimasa Aoto, Keika Adachi, Naoki Hayashi, Kimiko Amafuji, Nobuko Moritoki, Shinsuke Shibata, Nobuo Sasaki, Masashi Mita, Shun Tanemoto, Keiko Ono, Yohei Mikami, Jumpei Sasabe, Kaoru Takabayashi, Naoki Hosoe, Toshihiko Suzuki, Toshiro Sato, Koji Atarashi, Toshiaki Teratani, Haruhiko Ogata, Nobuhiro Nakamoto, Daisuke Shiomi, Hiroshi Ashida, Takanori Kanai
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 6, Pp 1011-1031 (2023)
Background & Aims: D-amino acids, the chiral counterparts of protein L-amino acids, were primarily produced and utilized by microbes, including those in the human gut. However, little was known about how orally administered or microbe-derived D-amino
Externí odkaz:
https://doaj.org/article/3561896e2e8b4eb4a814259518b66ff8
Autor:
Kentaro Ago, Narihito Nagoshi, Kent Imaizumi, Takahiro Kitagawa, Momotaro Kawai, Keita Kajikawa, Reo Shibata, Yasuhiro Kamata, Kota Kojima, Munehisa Shinozaki, Takahiro Kondo, Satoshi Iwano, Atsushi Miyawaki, Masanari Ohtsuka, Haruhiko Bito, Kenta Kobayashi, Shinsuke Shibata, Tomoko Shindo, Jun Kohyama, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Visualisation of the activity of neural grafts using engineered luciferase provides insights into the integration between the graft and host.
Externí odkaz:
https://doaj.org/article/1123478e34614555b85d810a078f5e88
Autor:
Tsubasa Saeki, Sho Yoshimatsu, Mitsuru Ishikawa, Chung-Chau Hon, Ikuko Koya, Shinsuke Shibata, Makoto Hosoya, Chika Saegusa, Kaoru Ogawa, Jay W. Shin, Masato Fujioka, Hideyuki Okano
Publikováno v:
Regenerative Therapy, Vol 20, Iss , Pp 165-186 (2022)
Introduction: Efficient induction of the otic placode, the developmental origin of the inner ear from human pluripotent stem cells (hPSCs), provides a robust platform for otic development and sensorineural hearing loss modelling. Nevertheless, there
Externí odkaz:
https://doaj.org/article/8f164e0c0729489aa06876e4cf1c3290