Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Shinsuke Oshima"'
Autor:
Chihiro Yagi, Akira Kimura, Keito Ishida, Takeshi Takahashi, Ryota Kai, Tatsuya Yamagishi, Shinsuke Oshima, Shuji Izumi, Arata Horii
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundPersistent postural-perceptual dizziness (PPPD) is a chronic vestibular syndrome often triggered by acute or episodic vestibular syndromes, such as Meniere’s disease (MD). According to the diagnostic criteria, PPPD may coexist with other
Externí odkaz:
https://doaj.org/article/aa22562122314e2c9556a5b88e359690
Autor:
Taketo Otsuka, Osamu Kitami, Kouji Kondo, Hisayuki Ota, Shinsuke Oshima, Akio Tsuchiya, Takatoshi Shirai, Koyata Fujii, Michihide Nakamure, Yasuhiro Shoji, Hisano Nakamura, Yasuko Masuda, Kenichi Komiyama, Kazunaga Yoshida, Yukio Ishikawa, Atsushi Iwaya, Sugata Takahashi, Minoru Okazaki, Muneki Hotomi, Noboru Yamanaka
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68711 (2013)
BACKGROUND: Acute otitis media (AOM) is one of the most common forms of bacterial infection and cause for clinic visits in children. The incidence of AOM was 0.9-1.2 episodes per person-year during the first 2 years of life in previous reports conduc
Externí odkaz:
https://doaj.org/article/cd4221fbc61543dfb776230cc1d521d5
Autor:
Yuka Morita, Yutaka Yamamoto, Arata Horii, Chihiro Yagi, Shinsuke Oshima, Kuniyuki Takahashi, Manabu Ogi
Publikováno v:
European Archives of Oto-Rhino-Laryngology. 276:1335-1340
To clarify the anatomical distribution of otosclerotic loci in otosclerosis. Ninety-five patients with surgically confirmed uni- or bilateral otosclerosis were enrolled into the study. Hypodense areas observed in the otic capsule by high-resolution c
Autor:
Tatsuaki Morokata, Shoji Takakura, Hidehiko Fukahori, Koji Nakamura, Shinsuke Oshima, Jun Hirose, Yasuyuki Higashi, Takahisa Noto, Susumu Tsujimoto, Masashi Maeda, Kaori Hanaoka
Publikováno v:
Transplant Immunology. 52:32-39
We examined the benefit of a loading dose of tacrolimus on the production of donor-specific antibodies (DSA), occurrence of acute rejection (AR) episodes, graft survival, and histological evidence of antibody-mediated rejection (ABMR) after kidney tr
Autor:
Fujiko Takamura, Erik E. Karrer, Yasuyuki Higashi, Steven J. Chapin, Margaret Neighbors, Sridhar Viswanathan, Hidekazu Mizuhara, Shinsuke Oshima, Yasutomo Fujii, Bruce H. Devens
Publikováno v:
International Immunopharmacology. 40:310-317
The CTLA4-Ig fusion proteins abatacept and belatacept inhibit CD28-mediated T cell activation by binding CD80 (B7-1) and CD86 (B7-2) costimulatory ligands and are clinically proven immunosuppressants used for rheumatoid arthritis and renal transplant
Autor:
Kuoting Wu, Clifford Wong, Margaret Neighbors, Erik E. Karrer, Yasuyuki Higashi, Madan M. Paidhungat, Steven J. Chapin, Steven H. Bass, Bruce H. Devens, Shinsuke Oshima, Margaret Reed, Brent R. Larsen, Yonghong Chen, Francisco A. Anderson, Marc Whitlow, Rujuta A. Bam, Sridhar Viswanathan, Rong A. Fan, Qian Zhang
Publikováno v:
Protein Engineering Design and Selection. 29:159-167
The CTLA4-Ig therapeutics abatacept and belatacept inhibit CD28-mediated T cell activation by binding CD80 (B7-1) and CD86 (B7-2) co-stimulatory ligands. Both compounds preferentially bind CD80, yet CD86 has been implicated as the dominant co-stimula
Autor:
Kaori Hanaoka, Hidehiko Fukahori, Yasuyuki Higashi, Masamichi Inami, Yuka Kawato, Terry Y. Nakagawa, Shinsuke Oshima, Koji Nakamura, Tatsuaki Morokata, Yutaka Nakajima, Kaori Kubo
Publikováno v:
European journal of pharmacology. 838
Donor-specific antibodies (DSA) are a major risk factor for antibody-mediated rejection (ABMR) in solid organ transplantation, and ABMR remains a medical challenge. Therefore, effective anti-ABMR therapies are needed to improve overall graft survival
Autor:
Tatsuaki Morokata, Shinsuke Oshima, Koji Nakamura, Masashi Maeda, Hidehiko Fukahori, Susumu Tsujimoto, Tomoko Kawashima, Jun Hirose, Mamoru Tasaki, Noboru Chida, Takahisa Noto, Yasuyuki Higashi
Publikováno v:
International Immunopharmacology. 27:232-237
Selective inhibition of protein kinase Cθ (PKCθ) may be useful in inducing T cell-specific immunosuppression with a reduced rate of side effects. To our knowledge, however, no reports have been published regarding the selective inhibition of PKCθ
Publikováno v:
European Archives of Oto-Rhino-Laryngology. 273:1155-1160
This study examined the differences between congenital cholesteatoma (CC) and acquired cholesteatomas (AC) in children by comparing clinical features and treatment courses. This was a retrospective study which retrospectively evaluated 127 children w
Autor:
Yasutomo Fujii, Takahisa Noto, Yasuyuki Higashi, Steven J. Chapin, Margaret Neighbors, Yuka Kawato, Shinsuke Oshima, B. Devens, Masashi Maeda, Sridhar Viswanathan, Susumu Tsujimoto, Jun Hirose, Hidehiko Fukahori, Fujiko Takamura, Erik E. Karrer, Koji Nakamura, Takanori Marui
Publikováno v:
Transplantation. 100(12)
Background Blockade of CD28-mediated T cell costimulation by a modified cytotoxic T lymphocyte-associated antigen 4 (CTLA4-Ig), belatacept, is a clinically effective immunosuppressive therapy for the prevention of renal allograft rejection. Use of be