Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shinsuke Kurosu"'
Autor:
Atsushi Nakajima, Sonoko Ishizaki, Kazuki Matsuda, Shinsuke Kurosu, Shinya Taniguchi, Per‐Göran Gillberg, Jan P Mattsson, Tomoko Hasunuma, Michael Camilleri
Publikováno v:
Journal of gastroenterology and hepatology. 37(5)
Elobixibat is a locally acting inhibitor of the ileal bile acid transporter. We compared bile acid metabolism between healthy subjects and patients with chronic constipation and assessed changes in the bile acid profile after elobixibat administratio
Autor:
Shinsuke Kurosu
Publikováno v:
Folia Pharmacologica Japonica. 150:4-9
Autor:
Shinya Taniguchi, Michael Camilleri, Shinsuke Kurosu, Tomoko Hasunuma, Sonoko Ishizaki, Per-Göran Gillberg, Atsushi Nakajima, Jan P. Mattsson
Publikováno v:
Gastroenterology. 158:S-394
Autor:
Shinya Taniguchi, Per Göran Gillberg, Michael Camilleri, Jan P. Mattsson, Shinsuke Kurosu, Atsushi Nakajima
Publikováno v:
Neurogastroenterology and Motility
Background In two phase 3 trials, elobixibat, a locally acting ileal bile acid transporter inhibitor, resolved constipation and was well tolerated in Japanese patients with chronic constipation. We analyzed the efficacy, safety, and impact on quality
Autor:
Michihiko Iijima, K Tokugawa, T Kuwada, Kenichi Fukumoto, Takao Yoshimizu, Yoshinori Sekiguchi, Shigeyuki Chaki, Toshiharu Shimazaki, Shinsuke Kurosu
Publikováno v:
British Journal of Pharmacology. 171:3511-3525
Background and Purpose Vasopressin V1B receptor antagonists may be effective for the treatment of depression and anxiety and the objective of this study was to characterize the pharmacological profiles of two newly synthesized arginine vasopressin re
Depolarizing stimuli cause persistent and selective loss of orexin in rat hypothalamic slice culture
Autor:
Yasuhiko Izumi, Yoichiro Isohama, Toshiaki Kume, Akinori Akaike, Shotaro Michinaga, Shinsuke Kurosu, Hiroshi Katsuki, Akinori Hisatsune
Publikováno v:
Peptides. 31:1131-1138
A hypothalamic neuropeptide orexin (hypocretin) is a critical regulator of physiological processes including sleep/wakefulness and feeding. Using organotypic slice culture of rat hypothalamus, we found that exposure to elevated extracellular concentr
Publikováno v:
Neuroscience Letters. 471:63-65
Accumulating evidence has implicated glutamatergic systems in psychiatric disorders. Abnormalities in glutamatergic systems have consistently been identified in obsessive-compulsive disorder (OCD). Marble-burying behavior has been described in litera