Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Shinseog Kim"'
Autor:
Nicole M. Sodir, Luca Pellegrinet, Roderik M. Kortlever, Tania Campos, Yong-Won Kwon, Shinseog Kim, Daniel Garcia, Alessandra Perfetto, Panayiotis Anastasiou, Lamorna Brown Swigart, Mark J. Arends, Trevor D. Littlewood, Gerard I. Evan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Happloinsufficiency of Myc delays onset of cancers in mice. Here, the authors generated a mouse model of reversible cMyc hypomorphism and show that metronomic reduction of c-Myc in adult mice confers protection against cancers without side effects an
Externí odkaz:
https://doaj.org/article/f2edbfdb52b64070a843f6b7ca3e272f
Autor:
Hyeongsun Jeong, Minwoo Wie, In-Joon Baek, Gyuwon Sohn, Si-Hyeon Um, Seon-Gyeong Lee, Yuri Seo, Jaesun Ra, Eun A Lee, Shinseog Kim, Byung Gyu Kim, Rajashree A. Deshpande, Tanya T. Paull, Joo Seok Han, Taejoon Kwon, Kyungjae Myung
Publikováno v:
Cells, Vol 11, Iss 24, p 4095 (2022)
Thyroid hormone receptor-interacting protein 13 (TRIP13) participates in various regulatory steps related to the cell cycle, such as the mitotic spindle assembly checkpoint and meiotic recombination, possibly by interacting with members of the HORMA
Externí odkaz:
https://doaj.org/article/4b2e977fd15442d1926016ad0d2944a2
Autor:
Shinseog Kim, Satoshi H Namekawa, Lisa M Niswander, Jeremy O Ward, Jeannie T Lee, Vivian J Bardwell, David Zarkower
Publikováno v:
PLoS Genetics, Vol 3, Iss 4, p e62 (2007)
Gametogenesis is a sexually dimorphic process requiring profound differences in germ cell differentiation between the sexes. In mammals, the presence of heteromorphic sex chromosomes in males creates additional sex-specific challenges, including inco
Externí odkaz:
https://doaj.org/article/95b85c70072640069cada68b01efea1d
Autor:
Eunjin Ryu, Juyeong Yoo, Mi-Sun Kang, Na Young Ha, Yewon Jang, Jinwoo Kim, Yeongjae Kim, Byung-Gyu Kim, Shinseog Kim, Kyungjae Myung, Sukhyun Kang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/20/2024, Vol. 121 Issue 34, p1-12, 49p
Autor:
KS Lee, Shinseog Kim, Su Hyung Park, Minwoo Wie, Jun Hong Park, Seong-Jung Kim, Tae Moon Kim, Kyungjae Myung
Publikováno v:
Cell Cycle
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Centrosomes are the primary microtubule-organizing centers that are important for mitotic spindle assembly. Centrosome amplification is commonly observed in human cancer cells and contributes to genomic instability. However, it is not clear how centr
Autor:
Daniel Garcia, Panayiotis Anastasiou, Shinseog Kim, Alessandra Perfetto, Yong-Won Kwon, Luca Pellegrinet, Lamorna Brown Swigart, Roderik M. Kortlever, Trevor D. Littlewood, Gerard I. Evan, Nicole M. Sodir
Myc+/−haploinsufficient mice and mice with deletedMycenhancers express reduced levels of the pleiotropic transcription factor Myc. Such mice are viable, with relatively mild pathologies, but show delay in onset of certain cancers. However, many phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96d8f521f2b0434eb1812d3b79a598fc
https://doi.org/10.1101/2020.12.30.422650
https://doi.org/10.1101/2020.12.30.422650
Publikováno v:
Journal of Mammalian Ova Research. 33:79-87
Mammalian primordial germ cells (PGCs) are specified in the early post-implantation embryo. Attempts have been made to establish in vitro PGC development since the derivation of embryonic stem cells (ESCs) from blastocysts. Despite the advances made
Autor:
In Bae Park, In‐Joon Baek, Jung Me Hwang, Hye Jin Kim, Namwoo Kim, Kyungjae Myung, Byung-Gyu Kim, Jun Hong Park, Shinseog Kim, Seon-gyeong Lee, Anton Gartner, Su‐min Kim
Publikováno v:
EMBO Rep
Poly(ADP-ribose) polymerase 1 (PARP1) facilitates DNA damage response (DDR). While the Ewing's sarcoma breakpoint region 1 (EWS) protein fused to FLI1 triggers sarcoma formation, the physiological function of EWS is largely unknown. Here, we investig
Autor:
Yanglin Chen, Fuchou Tang, Xihe Li, Siqin Bao, Sabine Dietmann, Walfred W. C. Tang, Jingyun Li, Caroline Lee, Lin Li, Baojiang Wu, Shinseog Kim, M. Azim Surani, Mengyi Wei, Shudong Li, Toshihiro Kobayashi
Publikováno v:
Cell Research
Naive hypomethylated embryonic pluripotent stem cells (ESCs) are developmentally closest to the preimplantation epiblast of blastocysts, with the potential to contribute to all embryonic tissues and the germline, excepting the extra-embryonic tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d3633be2eee4c911f12b7d14e11d6d
Publikováno v:
Transcription. 9(3)
There are hundreds of copies of rDNA repeats in mammalian chromosomes and the ratio of active, poised, or inactive rDNA is regulated in epigenetic manners. Recent studies demonstrated that a post-DNA replication repair enzyme, SHPRH affects rRNA tran