Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Shinsaku Maruta"'
Publikováno v:
Biosciences Biotechnology Research Asia. 18:661-672
Ras is a small G protein known as a central regulator of cellular signal transduction that induces processes, such as cell division, transcription. The hypervariable region (HVR) is one of the functional parts of this G protein, which induces multime
Autor:
Shinsaku Maruta, Daiki Morita, Makoto Miyata, Seigo Iwata, Yuhei O Tahara, Yasunobu Sugimoto, Rufiat Nahar
Publikováno v:
The Journal of Biochemistry. 171:215-225
The lipid-anchored small G protein Ras is a central regulator of cellular signal transduction processes, thereby functioning as a molecular switch. Ras forms a nanocluster on the plasma membrane by modifying lipids in the hypervariable region (HVR) a
Autor:
Yassine Sabek, Ziyun Zhang, Yuichi Imamura, Nobuyuki Nishibe, Kazunori Kondo, Shinsaku Maruta
Publikováno v:
Biophysical Journal. 122:434a
Autor:
Islam Md Alrazi, Shinsaku Maruta
Publikováno v:
Biophysical Journal. 122:410a
Autor:
Takayuki Miyanishi, Shinsaku Maruta, Kei Sadakane, Kenichi Taii, Yuka Kawata, Tomisin Happy Ogunwa
Publikováno v:
The Journal of Biochemistry. 166:129-137
Among 40 plant-derived biflavonoids with inhibitory potential against Eg5, morelloflavone from Garcinia dulcis leaves was selected for further testing based on in silico analysis of binding modes, molecular interactions, binding energies and function
Autor:
Olaposi I Omotuyi, Shinsaku Maruta, Ayodele O. Kolawole, Islam M D Alrazi, Olusola Olalekan Elekofehinti, Takayuki Miyanishi, Tomisin H Ogunwa
Publikováno v:
Journal of biochemistry. 170(5)
Mitotic kinesin Eg5 remains a validated target in antimitotic therapy because of its essential role in the formation and maintenance of bipolar mitotic spindles. Although numerous Eg5 inhibitors of synthetic origin are known, only a few inhibitors de
Publikováno v:
RSC advances. 11(2)
An intrinsically disordered protein, α-synuclein (αSyn), binds to negatively charged phospholipid membranes and adopts an α-helical structure. This conformational change is also induced by interaction with sodium dodecyl sulfate (SDS), which is an
Publikováno v:
Journal of biochemistry. 170(2)
The mitotic kinesin Eg5 is a plus-end directed homotetrameric molecular motor essential for the formation of bipolar spindles during cell division. Kinesin Eg5 is overexpressed in cancer cells and hence considered as a target for cancer therapy; the
Publikováno v:
Biophysical Journal. 121:421a
Autor:
Islam Md Alrazi, Shinsaku Maruta
Publikováno v:
Biophysical Journal. 121:400a