Výsledky vyhledávání - "Shinro Sadanobu"

Mutagenicity tests of 4-phenyl-1, 3-dithia-2-thioxo-cyclopent-4-ene

Autor: Colin G. Riach, Masakatsu Tezuka, Shinro Sadanobu, Michael L. Holmstrom, Ishbel A. Leddy

Publikováno v: The Journal of Toxicological Sciences. 24:87-94

The mutagenicity of 4-phenyl-1, 3-dithia-2-thioxo-cycLopent-4-ene (DT827B) was examined in reverse mutation tests using Salmonella tryphimurium and Escherichia coli, in the chromosomal aberration test with Chinese hamster ovary (CHO) cells, and in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c55b2f31c25ad8a50669005f250d338
https://doi.org/10.2131/jts.24.87

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In Vitro Effect of Chromium and Other Trace Metals on Mouse Hepatotoxicity Induced by Carbon Tetrachloride Exposure

Autor: Mariko Tachikawa, Shinro Sadanobu, Ryoji Sawamura, Kenji Gomi, Masakatsu Tezuka

Publikováno v: Biological and Pharmaceutical Bulletin. 18:256-261

Using primary cultured mouse hepatocytes, in vitro study was performed to discuss the effect of Cr(III) and several other trace metals, Cr(VI), Mn(II), Zn(II), Co(II), Cu(II), Ni(II), and Ga(III) on acute liver damage induced by CCl4 exposure. 1) The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb31888ababbec298201c5e7dcc9ee4
https://doi.org/10.1248/bpb.18.256

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In vitro tests of 1,3-dithia-2-thioxo-cyclopent-4-ene to evaluate the mechanisms of its hepatoprotective action

Autor: Masakatsu Tezuka, Shinro Sadanobu, Chika Nakamura, Masaki Watanabe

Publikováno v: The Journal of toxicological sciences. 24(5)

Some in vitro tests were performed using 1, 3-dithia-2-thioxo-cyclopent-4-ene (DT827A) to evaluate its mode of action on hepatoprotection. Experiments with leucine, uridine and thymidine uptakes using L-132 cells showed no increase in leucine uptake,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6624598fc1d417d2e78fdf57136772b
https://pubmed.ncbi.nlm.nih.gov/10656158

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Effect of 4-phenyl-1,3-dithia-2-thioxo-cyclopent-4-ene on liver injury induced by repeated exposure to galactosamine plus carbon tetrachloride in rats

Autor: Masaya Takeuchi, Masakatsu Tezuka, Shinro Sadanobu

Publikováno v: The Journal of toxicological sciences. 23(2)

The protective effects of 1,3-dithia-2-thioxo-cyclopent-4-ene (DT827A),4-phenyl-1,3-dithia-2-thioxo-cyclopent- 4-ene (DT827B) and 4-(4-fluorophenyl)-1,3-dithia-2-thioxo-cyclopent-4-ene (DT827C) on liver injury induced by D-galactosamine plus carbon t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a314b67e98883bc1839f798946063b46
https://pubmed.ncbi.nlm.nih.gov/9644653

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Effect of 1,3-dithia-2-thioxo-cyclopent-4-ene and its derivatives on liver injury induced by carbon tetrachloride and orotic acid in rats

Autor: Shinro Sadanobu, Masaya Takeuchi, Masakatsu Tezuka

Publikováno v: The Journal of toxicological sciences. 22(5)

The protective effect of 1,3-dithia-2-thioxo-cyclopent-4-ene (DT827A) and its two derivatives of 4-phenyl-1,3-dithia-2-thioxo-cyclopent-4-ene (DT827B) and 4-(4-fluorophenyl)-1,3-dithia-2-thioxo-cyclopent-4-ene (DT827C) on liver injury induced by carb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40010b4df34a4004985fe7fb9c084faa
https://pubmed.ncbi.nlm.nih.gov/9442451

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