Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shinpei Yoshida"'
Autor:
Takayuki Kuroda, Keita Fukao, Shinpei Yoshida, Ryoko Oka, Kaoru Baba, Yoshinori Ando, Keiichi Taniguchi, Takeshi Noshi, Takao Shishido
Publikováno v:
Viruses, Vol 15, Iss 5, p 1154 (2023)
Although the prevalence of polymerase acidic (PA)/I38T strains of influenza virus with reduced susceptibility to baloxavir acid is low, there is a possibility of emergence under selective pressure. Furthermore, the virus may be transmitted between hu
Externí odkaz:
https://doaj.org/article/10d935ba69ee4c45b0ca89d03f84d577
Autor:
Hisashi Wada, Tatsuya Takahashi, Mai Yoshikawa, Yoji Nagira, Morio Nagira, Tetsuya Yoshida, Shinpei Yoshida, Tetsuyoshi Soh, Naganari Ohkura
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/778c606d7b44434286e66455df73b85e
Autor:
Takayuki Kuroda, Haruaki Nobori, Keita Fukao, Kaoru Baba, Kazumi Matsumoto, Shinpei Yoshida, Yukari Tanaka, Ryosuke Watari, Ryoko Oka, Yasuyuki Kasai, Kae Inoue, Sho Kawashima, Alice Shimba, Yoko Hayasaki-Kajiwara, Miki Tanimura, Qianhui Zhang, Yuki Tachibana, Teruhisa Kato, Takao Shishido
Publikováno v:
Journal of Antimicrobial Chemotherapy. 78:946-952
Objectives Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become established in the human population, making the need to develop safe and effective treatments critical. We have developed the small-molecule antiviral ensitrelvir, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46e4838ce57f495c69db0e7a93c38576
https://doi.org/10.1093/jac/dkad027
https://doi.org/10.1093/jac/dkad027
Autor:
Michihito Sasaki, Koshiro Tabata, Mai Kishimoto, Yukari Itakura, Hiroko Kobayashi, Takuma Ariizumi, Kentaro Uemura, Shinsuke Toba, Shinji Kusakabe, Yuki Maruyama, Shun Iida, Noriko Nakajima, Tadaki Suzuki, Shinpei Yoshida, Haruaki Nobori, Takao Sanaki, Teruhisa Kato, Takao Shishido, William W. Hall, Yasuko Orba, Akihiko Sato, Hirofumi Sawa
Publikováno v:
Science Translational Medicine. 15
In parallel with vaccination, oral antiviral agents are highly anticipated to act as countermeasures for the treatment of the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Oral an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41abaf8121b7123fc1eb593dde8e7a8c
https://doi.org/10.1126/scitranslmed.abq4064
https://doi.org/10.1126/scitranslmed.abq4064
Autor:
Kana Horiuchi, Hiroki Koshimichi, Takanobu Matsuzaki, Ryosuke Shimizu, Shinpei Yoshida, Ryuji Kubota, Shingo Sakamoto
Publikováno v:
Open Forum Infectious Diseases. 9
Background Ensitrelvir is a novel oral SARS-CoV-2 3C-like protease inhibitor, and under late clinical development stage for COVID-19 diseases. Ensitrelvir exhibited an inhibition potency for organic cation transporter 1 (OCT1) and multidrug and toxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::256621c860a9502c52d8a5b8f9163f1b
https://doi.org/10.1093/ofid/ofac492.975
https://doi.org/10.1093/ofid/ofac492.975
Autor:
Hiroyuki Kusuhara, Sylvia Leo, Takayuki Honjo, Shinpei Yoshida, Ryunosuke Ishibe, Teruhiko Watanabe, Nobuaki Shiraki, Shoen Kume, Masaya Ishikawa, Tomoka Shimada, Kazuya Maeda, Keita Iino
Publikováno v:
Stem Cell Reports
Summary We aimed to establish an in vitro differentiation procedure to generate matured small intestinal cells mimicking human small intestine from human-induced pluripotent stem cells (iPSCs). We previously reported the efficient generation of CDX2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40216d5766333736c500bca46377dd5b
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100852303
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100852303
Autor:
Yuichi Tozuka, Naomi Tamura, Shiro Miyazaki, Kazunori Kadota, Hidekazu Tsutsumimoto, Shinpei Yoshida, Masaaki Imono, Hiromasa Uchiyama
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 146:84-92
Nanocrystal formulation is a well-established approach for improving oral absorption of poorly water-soluble drugs. However, it is difficult to predict the in vivo performance of nanocrystal formulations from in vitro dissolution studies. The object
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef611543c1e096cf1215b57d7e22283
https://doi.org/10.1016/j.ejpb.2019.12.002
https://doi.org/10.1016/j.ejpb.2019.12.002
Autor:
Michihito Sasaki, Koshiro Tabata, Mai Kishimoto, Yukari Itakura, Hiroko Kobayashi, Takuma Ariizumi, Kentaro Uemura, Shinsuke Toba, Shinji Kusakabe, Yuki Maruyama, Shun Iida, Noriko Nakajima, Tadaki Suzuki, Shinpei Yoshida, Haruaki Nobori, Takao Sanaki, Teruhisa Kato, Takao Shishido, William W. Hall, Yasuko Orba, Akihiko Sato, Hirofumi Sawa
In parallel with vaccination, oral antiviral agents are highly anticipated to act as countermeasures for the treatment of the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Oral an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0cd5d8e6182084f0d894f08b1ffa234
https://doi.org/10.1101/2022.02.14.480338
https://doi.org/10.1101/2022.02.14.480338
Autor:
Yoji Nagira, Tatsuya Takahashi, Tetsuya Yoshida, Tetsuyoshi Soh, Mai Yoshikawa, Morio Nagira, Hisashi Wada, Naganari Ohkura, Shinpei Yoshida
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundRegulatory T cells (Tregs) are involved in tumor progression and inhibition of anti-tumor immune responses by promotion of immunological tolerance in the tumor microenvironment. On the other hand, Treg cells in peripheral blood are also ess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f322fa531510b0e7496be15912967f64
https://doi.org/10.1136/jitc-2021-sitc2021.891
https://doi.org/10.1136/jitc-2021-sitc2021.891
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Drug absorption via the intestinal tissue is modulated by membrane permeability and metabolism in intestinal epithelial cells (IECs). In drug discovery research, using human IECs to evaluate membrane permeability and metabolic stability can offer ver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88bb325467289f9451ec51115ed9d5a
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100835585
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100835585