Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Shinobu Umemura"'
Autor:
Shinobu Umemura, Yasuhiro Suzuki, Risa Ohshitanai, Naoki Niikura, Takuho Okamura, Yutaka Tokuda, Tohru Morioka, Yuki Saito, Banri Tsuda, Mayako Terao, Mizuho Terada
Publikováno v:
Nihon Nyugan Kenshin Gakkaishi (Journal of Japan Association of Breast Cancer Screening). 21:78-81
Autor:
Xiaoyan Tang, Yasuhiro Suzuki, Akira Ozawa, Nobue Kumaki, Yuki Saito, Miki Izumi, Shinobu Umemura, Yutaka Tokuda
Publikováno v:
Breast Cancer. 21:370-374
A 43-year-old Japanese woman consulted our hospital for a pigmented lesion on her right nipple. Two years later, the lesion became enlarged, measuring 5 × 5 mm. It was dark brown, had an irregular shape and relatively clear borders. Incisional biops
Autor:
Nobuaki Kato, Shinobu Umemura, Hitoshi Itoh, Yutaka Hatanaka, R. Yoshiyuki Osamura, Akihiko Serizawa
Publikováno v:
Pathology International. 60:510-515
Fluorescence in situ hybridization (FISH) assay is considered the ‘gold standard’ for evaluation of HER2/neu (HER2) gene status, however, it is difficult to recognize morphologic features of tumors using fluorescence microscopy. Thus, chromogenic
Autor:
Robert Yoshiyuki Osamura, Kazushige Mori, Shinobu Umemura, Susumu Takekoshi, Yutaka Tokuda, Masatoshi Shirane
Publikováno v:
Oncology Letters. 1:261-266
Expression of the estrogen receptor (ER), the progesterone receptor (PgR) or the human epidermal growth factor receptor-2 (HER2) in tumors is a good prognostic marker for breast cancer patients. However, approximately 15–20% of breast cancer patien
Publikováno v:
Breast Cancer. 16:295-300
Currently, trastuzumab is one of the key drugs in the treatment strategy for HER2-positive breast cancer. Although metastatic breast cancer is unlikely to be cured, some HER2-positive patients have survived for a long time with complete response to t
Autor:
Susumu Takekoshi, Yoshiyuki Osamura, Masatoshi Shirane, Noboru Egashira, T Kusakabe, Johbu Itoh, Shinobu Umemura, Yutaka Tokuda, K. Mori
Publikováno v:
British Journal of Cancer
The purpose of the present study is to identify genes that contribute to cell proliferation or differentiation of breast cancers independent of signalling through the oestrogen receptor (ER) or human epidermal growth factor receptor 2 (HER2). An olig
Autor:
Susumu Takekoshi, Sunao Shoji, Masanori Shima, Shinobu Umemura, Johbu Itoh, Yukio Usui, Toshiro Terachi, Xian Yan Tang, Robert Yoshiyuki Osamura, Toyoaki Uchida, Yoshihiro Nagata
Publikováno v:
European Urology. 55:441-451
Background Metastin, the final peptide of the KiSS-1 gene, has been proposed to suppress cell motility. Objective This study investigated whether renal cell carcinoma (RCC) tissue expresses metastin or its receptor, and clarified whether metastin can
Autor:
Nobuaki Kato, Akihiko Serizawa, Yoko Miyajima, Tomohisa Machida, Shinobu Umemura, Yoshiyuki Osamura, Hitoshi Itoh
Publikováno v:
The Journal of the Japanese Society of Clinical Cytology. 48:257-262
Autor:
Hitoshi Tsuda, Masafumi Kurosumi, Satoshi Toyoshima, Keiichi Honma, Goi Sakamoto, Josef Rüschoff, Shinobu Umemura, Futoshi Akiyama, R. Yoshiyuki Osamura, Hironobu Sasano
Publikováno v:
American Journal of Clinical Pathology. 130:883-891
We assessed interinstitutional and interobserver consistency of human epidermal growth factor receptor type-2 (HER2) testing using immunohistochemical analysis and fluorescence in situ hybridization (FISH) in a set of 20 breast cancer samples among 1
Publikováno v:
Cancer. 114:134-140
BACKGROUND Fluorescence in situ hybridization (FISH) is the gold standard for assessing HER-2 status for breast cancers, and paraffin-embedded tissue sections are used routinely for HER-2 FISH. Cytologic samples also are used, but to the authors' kno