Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shinobu Komiya"'
Chemical Synthesis of O-Glycosylated Human Interleukin-2 by the Reverse Polarity Protection Strategy
Autor:
Hiroko Tamagaki, Katsuhiro Nakagawa, Rina Fujimoto, Akira Ishii, Yuya Asahina, Yoshiaki Nakahara, Shinobu Komiya, Toshifumi Takao, Ami Ohagi, Shizuo Akira, Takashi Sato, Hironobu Hojo
Publikováno v:
Angewandte Chemie. 127:8344-8348
The chemical synthesis of human interleukin-2 (IL-2) , having a core 1 sugar, by a ligation method is reported. Although IL-2 is a globular glycoprotein, its C-terminal region, in particular (99-133), is extremely insoluble when synthesized by solid-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84626896b778da61d12207d39899c1c
https://doi.org/10.1002/ange.201501847
https://doi.org/10.1002/ange.201501847
Autor:
Kyung S. Lee, Shinobu Komiya, Mija Ahn, Nam Kim, Bonsu Ku, Tae Sung Kim, Suk Youl Park, Seung Jun Kim, Jung-Eun Park, Ju Hee Kim, Jeong K. Bang, Ki Won Lee, Byung-Ha Oh, Wei Yang, Lan Tian, Raymond L. Erikson, Bo Yeon Kim, Mi Jeong Kwak, Hironobu Hojo, Ravichandran N. Murugan
Publikováno v:
Nature structural & molecular biology
Polo-like kinase 4 (Plk4) is a key regulator of centriole duplication, an event critical for the maintenance of genomic integrity. Here we showed that Plk4 relocalizes from the inner Cep192 ring to the outer Cep152 ring as newly recruited Cep152 asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39169a8e98481c79adbf14b33483b2ee
https://doi.org/10.1038/nsmb.2846
https://doi.org/10.1038/nsmb.2846
Publikováno v:
Tribology Online, Vol 14, Iss 5, Pp 312-320 (2019)
The lubrication behavior of mica–alkyl ammonium cation hybrid solid lubricants fabricated via an intercalation reaction was evaluated by reciprocating sliding tests, and the lubrication mechanism was investigated from the viewpoint of interlayer ad
Externí odkaz:
https://doaj.org/article/01f1b6786e5b44f4b3f2fd6f85be730b
Autor:
Yuya Asahina, Shinobu Komiya, Ami Ohagi, Rina Fujimoto, Hiroko Tamagaki, Katsuhiro Nakagawa, Takashi Sato, Shizuo Akira, Toshifumi Takao, Akira Ishii, Yoshiaki Nakahara, Hironobu Hojo
Publikováno v:
Angewandte Chemie International Edition; 7/6/2015, Vol. 54 Issue 28, p8226-8230, 5p
Publikováno v:
Tribology Online, Vol 12, Iss 4, Pp 193-202 (2017)
It is well known that the surface roughness of metal substrates considerably influences the tribological properties of solid lubricants. In this study, the surfaces of metal substrates were modified by wet-blasting and polishing, and the lubrication
Externí odkaz:
https://doaj.org/article/01e3eaf1b0a24679a5cd62c9a2a6c4b6