Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Shino Niki"'
Autor:
Masashi Yano, Shino Niki, Yasuhiro Mouri, Fumiko Hirota, Hongwei Han, Yoshimi Bando, Mitsuru Matsumoto, Keisuke Izumi, Akemi Matsushima, Noriyuki Kuroda, Masaki Matsumoto, Keiichi I. Nakayama, Kiyotaka Oshikawa
Publikováno v:
Journal of Clinical Investigation. 116:1292-1301
Factors that determine the spectrum of target organs involved in autoimmune destruction are poorly understood. Although loss of function of autoimmune regulator (AIRE) in thymic epithelial cells is responsible for autoimmunity, the pathogenic roles o
Autor:
Fumiko Hirota, Shizuo Akira, Minoru Irahara, Yasuhiro Mouri, Yoshimi Bando, Kiyoshi Takeda, Noriyuki Kuroda, Dan Kinoshita, Shino Niki, Michiyuki Kasai, Tsuneyasu Kaisho, Akemi Matsushima, Mitsuru Matsumoto, Keisuke Izumi, Hongwei Han, Masahiko Maegawa, Kiyotaka Oshikawa
Publikováno v:
The Journal of Immunology. 176:3995-4002
IκB kinase (IKK) α exhibits diverse biological activities through protein kinase-dependent and -independent functions, the former mediated predominantly through a noncanonical NF-κB activation pathway. The in vivo function of IKKα, however, still