Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shino Endo"'
Autor:
Tokiwa Motonari, Yuki Yoshino, Moe Haruta, Shino Endo, Shota Sasaki, Minoru Miyashita, Hiroshi Tada, Gou Watanabe, Toshiro Kaneko, Takanori Ishida, Natsuko Chiba
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Homologous recombination (HR) repairs DNA damage including DNA double-stranded breaks and alterations in HR-related genes results in HR deficiency. Germline alteration of HR-related genes, such as BRCA1 and BRCA2, causes hereditary breast an
Externí odkaz:
https://doaj.org/article/4e2508586b1c4525b4ec0ac5203eb4d5
Publikováno v:
Cancer Research Communications. 1:90-105
Homologous recombination (HR)-deficient cells are sensitive to PARP inhibitors through a synthetic lethal effect. We previously developed an HR activity assay named Assay of Site-Specific HR Activity (ASHRA). Here, we evaluated the HR activity of 30
Autor:
Huicheng Qi, Megumi Kikuchi, Yuki Yoshino, Zhenzhou Fang, Kazune Ohashi, Takato Gotoh, Ryo Ideta, Ayako Ui, Shino Endo, Kei Otsuka, Norihisa Shindo, Kohsuke Gonda, Chikashi Ishioka, Yoshio Miki, Tokuro Iwabuchi, Natsuko Chiba
Publikováno v:
Cancer scienceREFERENCES.
Breast cancer gene 1 (BRCA1) plays roles in DNA repair and centrosome regulation and is involved in DNA damage-induced centrosome amplification (DDICA). Here, the centrosomal localization of BRCA1 and the kinases involved in centrosome duplication we
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Homologous recombination (HR) contributes to the repair of DNA double-strand breaks (DSBs) and inter-strand crosslinks. The HR activity in cancer cells can be used to predict their sensitivity to DNA-damaging agents that cause these damages. To evalu
Autor:
Kazuha Shindo, Yuki Yoshino, Shino Endo, Natsuko Chiba, Ryo Kanazawa, Huicheng Qi, Akihiro Kobayashi, Zhenzhou Fang
Publikováno v:
Journal of Cell Science.
Breast cancer gene 1 (BRCA1) contributes to the regulation of centrosome number. We previously identified receptor for activated C kinase 1 (RACK1) as a BRCA1-interacting partner. RACK1, a scaffold protein that interacts with multiple proteins throug
Autor:
Huicheng Qi, Ryo Kanazawa, Mami Sugamata, Shin Ichiro Kanno, Shino Endo, Tatsuro Shimaoka, Yuki Yoshino, Ayako Matsuzawa, Kenta Suzuki, Akihiro Kobayashi, Chikashi Ishioka, Yutaro Miyanishi, Akira Yasui, Kazuha Shindo, Natsuko Chiba, Shun Shibata
Publikováno v:
Oncogene. 38(16)
Breast cancer gene 1 (BRCA1) is a tumor suppressor that is associated with hereditary breast and ovarian cancer. BRCA1 functions in DNA repair and centrosome regulation together with BRCA1-associated RING domain protein (BARD1), a heterodimer partner
Autor:
Yuki Yoshino, Akihiro Kobayashi, Huicheng Qi, Shino Endo, Zhenzhou Fang, Kazuha Shindo, Ryo Kanazawa, Natsuko Chiba
Publikováno v:
Journal of Cell Science; 2020, Vol. 133 Issue 17, p1-15, 15p