Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shinnosuke Shiono"'
Cortical parvalbumin neurons are responsible for homeostatic sleep rebound through CaMKII activation
Autor:
Kazuhiro Kon, Koji L. Ode, Tomoyuki Mano, Hiroshi Fujishima, Riina R. Takahashi, Daisuke Tone, Chika Shimizu, Shinnosuke Shiono, Saori Yada, Kyoko Matsuzawa, Shota Y. Yoshida, Junko Yoshida Garçon, Mari Kaneko, Yuta Shinohara, Rikuhiro G. Yamada, Shoi Shi, Kazunari Miyamichi, Kenta Sumiyama, Hiroshi Kiyonari, Etsuo A. Susaki, Hiroki R. Ueda
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The homeostatic regulation of sleep is characterized by rebound sleep after prolonged wakefulness, but the molecular and cellular mechanisms underlying this regulation are still unknown. In this study, we show that Ca2+/calmodulin-dependent
Externí odkaz:
https://doaj.org/article/1820ed7e972241e4b90b7d9e83e720d1
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 7, Pp 1302-1310 (2019)
Abstract Objective Progesterone is a potent neuromodulator that exerts effects on the brain through neurosteroids, progesterone receptors (PRs), and other molecules. Whether PR activation regulates seizures is not known. We determined whether PR acti
Externí odkaz:
https://doaj.org/article/bb4d3b6152ca45ca834b3af4f7d2a532
Cortical parvalbumin neurons are responsible for homeostatic sleep rebound through CaMKII activation
Autor:
Kazuhiro Kon, Koji L. Ode, Tomoyuki Mano, Hiroshi Fujishima, Daisuke Tone, Chika Shimizu, Shinnosuke Shiono, Saori Yada, Junko Yoshida Garçon, Mari Kaneko, Yuta Shinohara, Riina R. Takahashi, Rikuhiro G. Yamada, Shoi Shi, Kenta Sumiyama, Hiroshi Kiyonari, Etsuo A. Susaki, Hiroki R. Ueda
The homeostatic regulation of sleep is characterized by rebound sleep after prolonged wakefulness, but the molecular and cellular mechanisms underlying this regulation are still unknown. We show here that CaMKII-dependent activity control of parvalbu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea5bd4b9d9ddb6494fa3545ae2cac0df
https://doi.org/10.1101/2023.04.29.537929
https://doi.org/10.1101/2023.04.29.537929
Publikováno v:
Annals of Neurology. 91:682-696
Bilateral synchronous cortical activity occurs during sleep, attention, and seizures. Canonical models place the thalamus at the center of bilateral cortical synchronization because it generates bilateral sleep spindle oscillations and primarily gene
Publikováno v:
Brain
There are no detailed descriptions of neuronal circuit active during frontal lobe motor seizures. Using activity reporter mice, local field potential recordings, tissue clearing, viral tracing, and super-resolution microscopy, we found neuronal activ
Autor:
Anastasia, Brodovskaya, Shinnosuke, Shiono, Tamal, Batabyal, John, Williamson, Jaideep, Kapur
Publikováno v:
Journal of visualized experiments : JoVE. (181)
Researchers often need to record local field potentials (LFPs) simultaneously from several brain structures. Recording from multiple desired brain regions requires different microelectrode designs, but commercially available microelectrode arrays oft
Publikováno v:
Journal of Visualized Experiments.
Autor:
Sho Carl Shibata, Ayumi Shintani, Yuji Fujino, Daijiro Kabata, Shinnosuke Shiono, Takehiko Ikeda
Publikováno v:
Journal of Anesthesia. 34:694-701
We evaluated the influence of anesthetic management with sevoflurane or propofol on recurrence in patients undergoing breast cancer surgery. This single center, retrospective study, included patients who received either sevoflurane or propofol during
Autor:
John Williamson, Jaideep Kapur, Tamal Batabyal, Huayu Sun, Aleksandra Labuz, Suchitra Joshi, Shinnosuke Shiono
Publikováno v:
Epilepsia
OBJECTIVE Emerging evidence raises the possibility that progesterone receptor (PR) signaling may contribute to the reproductive hormone fluctuation-linked seizure precipitation, called catamenial epilepsy. Therefore, we studied PR isoform expression
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 7, Pp 1302-1310 (2019)
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology
Objective Progesterone is a potent neuromodulator that exerts effects on the brain through neurosteroids, progesterone receptors (PRs), and other molecules. Whether PR activation regulates seizures is not known. We determined whether PR activation in