Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shinjiro Watanabe"'
Autor:
Shinjiro Watanabe, Yoshikazu Fujimori, Akane Matsuzawa, Jun‐ichi Kobayashi, Hideaki Hirasawa, Yosuke Mutai, Fumiya Tanada
Publikováno v:
Neurourology and Urodynamics. 41:1336-1343
Transient receptor potential melastatin 8 (TRPM8) has a role in the abnormal sensory transduction of the bladder and is involved in the pathophysiology of hyperactivity bladder disorders. The aim of this study is to examine the effects of KPR-5714, a
Autor:
Takeshi Nakabayashi, Noboru Kamada, Masayuki Isaji, Nobuhiko Fushimi, Masahiro Hiratochi, Hideki Fujikura, Kazuya Tatani, Isao Azumaya, Koichi Arakawa, Yoshikazu Fujimori, Kazuo Shimizu, Hidemasa Hikawa, Kenji Katsuno, Toshihiro Nishimura, Shinjiro Watanabe
Publikováno v:
Bioorganicmedicinal chemistry. 34
We optimized the structure of an active metabolite (1) of WAY-123783, which was obtained from mouse urine after oral administration, to improve selectivity for SGLT2 and oral bioavailability. O-glucoside derivative 24 (remogliflozin etabonate) was su
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:3-B
Autor:
Yuji Yamauchi, Shinjiro Watanabe, Yu Kuramochi, Fumiaki Itoh, Satoshi Shuto, Norihiko Kikuchi, Masahiro Hiratochi, Kazuya Tatani, Masayuki Isaji
Publikováno v:
Journal of Medicinal Chemistry. 59:3719-3731
To test the hypothesis that inhibitors of human concentrative nucleoside transporter 2 (hCNT2) suppress increases in serum urate levels derived from dietary purines, we previously identified adenosine derivative 1 as a potent hCNT2 inhibitor (IC50 =
Autor:
Ayumi Tanaka, Masaaki Tsuda, Hironori Izumi, Hiroyuki Okuno, Hiroshi Takemori, Ran Inoue, Minami Inoue, Haruhiko Bito, Yuki Kuwana, Shinjiro Watanabe, Ichiro Takasaki, Mamoru Fukuchi, Hidetoshi Komatsu, Hisashi Mori, Akiko Tabuchi
Publikováno v:
The Journal of Neuroscience. 35:5606-5624
Although coordinated molecular signaling through excitatory and modulatory neurotransmissions is critical for the induction of immediate early genes (IEGs), which lead to effective changes in synaptic plasticity, the intracellular mechanisms responsi
Autor:
Mamoru, Fukuchi, Akiko, Tabuchi, Yuki, Kuwana, Shinjiro, Watanabe, Minami, Inoue, Ichiro, Takasaki, Hironori, Izumi, Ayumi, Tanaka, Ran, Inoue, Hisashi, Mori, Hidetoshi, Komatsu, Hiroshi, Takemori, Hiroyuki, Okuno, Haruhiko, Bito, Masaaki, Tsuda
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(14)
Although coordinated molecular signaling through excitatory and modulatory neurotransmissions is critical for the induction of immediate early genes (IEGs), which lead to effective changes in synaptic plasticity, the intracellular mechanisms responsi
Autor:
Kazuya Tatani, Masahiro Hiratochi, Norihiko Kikuchi, Yu Kuramochi, Shinjiro Watanabe, Yuji Yamauchi, Fumiaki Itoh, Masayuki Isaji, Satoshi Shuto
Publikováno v:
Journal of Medicinal Chemistry; Apr2016, Vol. 59 Issue 8, p3719-3731, 13p
Autor:
Yuki Kuwana, Shinjiro Watanabe, Mamoru Fukuchi, Masaaki Tsuda, Akiko Tabuchi, Ichiro Takasaki
Publikováno v:
Neuroscience Research. 68:e352
Autor:
Mamoru Fukuchi, Akiko Tabuchi, Yuki Kuwana, Shinjiro Watanabe, Minami Inoue, Ichiro Takasaki, Hironori Izumi, Ayumi Tanaka, Ran Inoue, Hisashi Mori, Hidetoshi Komatsu, Hiroshi Takemori, Hiroyuki Okuno, Haruhiko Bito, Masaaki Tsuda
Publikováno v:
Journal of Neuroscience; 4/8/2015, Vol. 35 Issue 14, p5606-5624, 19p
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