Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Shinjiro OJIMA"'
Autor:
Aa Haeruman Azam, Kohei Kondo, Kotaro Chihara, Tomohiro Nakamura, Shinjiro Ojima, Wenhan Nie, Azumi Tamura, Wakana Yamashita, Yo Sugawara, Motoyuki Sugai, Longzhu Cui, Yoshimasa Takahashi, Koichi Watashi, Kotaro Kiga
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Retrons are bacterial genetic elements that encode a reverse transcriptase and, in combination with toxic effector proteins, can serve as antiphage defense systems. However, the mechanisms of action of most retron effectors, and how phages e
Externí odkaz:
https://doaj.org/article/aad2a50b93b54437b15cd98f19d20d29
Autor:
Azumi Tamura, Aa Haeruman Azam, Tomohiro Nakamura, Kenichi Lee, Sunao Iyoda, Kohei Kondo, Shinjiro Ojima, Kotaro Chihara, Wakana Yamashita, Longzhu Cui, Yukihiro Akeda, Koichi Watashi, Yoshimasa Takahashi, Hiroshi Yotsuyanagi, Kotaro Kiga
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Escherichia coli O157 can cause foodborne outbreaks, with infection leading to severe disease such as hemolytic-uremic syndrome. Although phage-based detection methods for E. coli O157 are being explored, research on their specificity with c
Externí odkaz:
https://doaj.org/article/cc0b28c1d9984e26bc9ee9a74bee0d71
Autor:
Aa Haeruman Azam, Koji Sato, Kazuhiko Miyanaga, Tomohiro Nakamura, Shinjiro Ojima, Kohei Kondo, Azumi Tamura, Wakana Yamashita, Yasunori Tanji, Kotaro Kiga
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Escherichia coli O157:H7 is a globally important foodborne pathogen with implications for food safety. Antibiotic treatment for O157 may potentially contribute to the exacerbation of hemolytic uremic syndrome, and the increasing prevalence o
Externí odkaz:
https://doaj.org/article/1883ce4214bb4305bcfc2aabfa4f99e9
Autor:
Zuo Hu, Shinjiro Ojima, Zhihao Zhu, Xiaoying Yu, Makoto Sugiyama, Takeshi Haneda, Masashi Okamura, Hisaya K. Ono, Dong-Liang Hu
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Salmonella enterica serovar Gallinarum (S. gallinarum) is an important host-specific pathogen that causes fowl typhoid, a severe systemic, septicemic, and fatal infection, in chickens. S. gallinarum causes high morbidity and mortality in chickens and
Externí odkaz:
https://doaj.org/article/a76395708ca247e3a1841187b3287b71
Autor:
Wakana Yamashita, Shinjiro Ojima, Azumi Tamura, Aa Haeruman Azam, Kohei Kondo, Zhang Yuancheng, Longzhu Cui, Masaki Shintani, Masato Suzuki, Yoshimasa Takahashi, Koichi Watashi, Satoshi Tsuneda, Kotaro Kiga
Publikováno v:
BioDesign Research, Vol 6 (2024)
The global increase in the prevalence of drug-resistant bacteria has necessitated the development of alternative treatments that do not rely on conventional antimicrobial agents. Using bacteriophage-derived lytic enzymes in antibacterial therapy show
Externí odkaz:
https://doaj.org/article/e6648894c7274c73982c6f8070c4657f
Autor:
Zhihao Zhu, Zuo Hu, Shinjiro Ojima, Xiaoying Yu, Makoto Sugiyama, Hisaya K. Ono, Dong-Liang Hu
Publikováno v:
Microorganisms, Vol 12, Iss 6, p 1180 (2024)
Salmonella enterica serovar Gallinarum biovar Gallinarum (SG) causes fowl typhoid, a notifiable infectious disease in poultry. However, the pathogenic mechanism of SG-induced systemic infection in chickens remains unclear. Thioredoxin reductase (TrxB
Externí odkaz:
https://doaj.org/article/581a8105e42c44af94b73b0a9748c4fb
Autor:
Takayuki Hishiki, Takeshi Morita, Daisuke Akazawa, Hirofumi Ohashi, Eun-Sil Park, Michiyo Kataoka, Junki Mifune, Kaho Shionoya, Kana Tsuchimoto, Shinjiro Ojima, Aa Haeruman Azam, Shogo Nakajima, Madoka Kawahara, Tomoki Yoshikawa, Masayuki Shimojima, Kotaro Kiga, Ken Maeda, Tadaki Suzuki, Hideki Ebihara, Yoshimasa Takahashi, Koichi Watashi
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Mpox virus (formerly monkeypox virus [MPXV]) is a neglected zoonotic pathogen that caused a worldwide outbreak in May 2022. Given the lack of an established therapy, the development of an anti-MPXV strategy is of vital importance. To identif
Externí odkaz:
https://doaj.org/article/9162094e82eb4dd4b7a19db6b082afe0
Autor:
Shinjiro Ojima, Hisaya K. Ono, Ryo Okimoto, Xiaoying Yu, Makoto Sugiyama, Kazuki Yoshioka, Takeshi Haneda, Masashi Okamura, Dong-Liang Hu
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Salmonella enterica serovar Gallinarum (S. Gallinarum) is a host-specific pathogen causing fowl typhoid, a severe systemic infection in poultry, which leads to substantial economic losses due to high morbidity and mortality in many developing countri
Externí odkaz:
https://doaj.org/article/1823e6e44a8847789a1e759f462aac5c
Autor:
Aa Haeruman Azam, Kotaro Chihara, Kohei Kondo, Tomohiro Nakamura, Shinjiro Ojima, Azumi Tamura, Wakana Yamashita, Longzhu Cui, Yoshimasa Takahashi, Koichi Watashi, Kotaro Kiga
Retrons are bacterial genetic retroelements that encode reverse transcriptase capable of producing multicopy single-stranded DNA (msDNA) and function as antiphage defense systems. Phages employ several strategies to counter the host defense systems,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7142751ecf7e573aef046967087abfb1
https://doi.org/10.1101/2023.03.15.532788
https://doi.org/10.1101/2023.03.15.532788
Autor:
Daisuke Akazawa, Hirofumi Ohashi, Takayuki Hishiki, Takeshi Morita, Shoya Iwanami, Kwang Su Kim, Yong Dam Jeong, Eun-Sil Park, Michiyo Kataoka, Kaho Shionoya, Junki Mifune, Kana Tsuchimoto, Shinjiro Ojima, Aa Haeruman Azam, Shogo Nakajima, Hyeongki Park, Tomoki Yoshikawa, Masayuki Shimojima, Kotaro Kiga, Shingo Iwami, Ken Maeda, Tadaki Suzuki, Hideki Ebihara, Yoshimasa Takahashi, Koichi Watashi
Publikováno v:
The Journal of Infectious Diseases.
Background Mpox virus (MPXV) is a zoonotic orthopoxvirus and caused an outbreak in 2022. Although tecovirimat and brincidofovir are approved as anti-smallpox drugs, their effects in mpox patients have not been well documented. In this study, by a dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::560288e1e58ba5c0fabba41f725e4e09
https://doi.org/10.1093/infdis/jiad058
https://doi.org/10.1093/infdis/jiad058