Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Shinjiro Kodama"'
Autor:
Masato Kohata, Shinjiro Kodama, Nobuhiro Yaoita, Shinichiro Hosaka, Kei Takahashi, Keizo Kaneko, Junta Imai, Satoshi Yasuda, Hideki Katagiri
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 8, Pp 1005-1008 (2023)
Abstract A 25‐year‐old man was diagnosed with diabetic ketoacidosis (DKA) at the onset of fulminant type 1 diabetes. After acute‐phase DKA treatment including placement of a central venous catheter, a massive deep vein thrombosis (DVT) and pulm
Externí odkaz:
https://doaj.org/article/260cb9d808154ca5ac6fd01a01bb6ba1
Autor:
Hiroto Sugawara, Junta Imai, Junpei Yamamoto, Tomohito Izumi, Yohei Kawana, Akira Endo, Masato Kohata, Junro Seike, Haremaru Kubo, Hiroshi Komamura, Yuichiro Munakata, Yoichiro Asai, Shinichiro Hosaka, Shojiro Sawada, Shinjiro Kodama, Kei Takahashi, Keizo Kaneko, Hideki Katagiri
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Cell proliferation processes play pivotal roles in timely adaptation to many biological situations. Herein, we establish a highly sensitive and simple strategy by which time-series showing the proliferation of a targeted cell type can be qua
Externí odkaz:
https://doaj.org/article/a64743050e8849b4a576987533ebe56b
Autor:
Haremaru Kubo, Shojiro Sawada, Michihiro Satoh, Yoichiro Asai, Shinjiro Kodama, Toshihiro Sato, Seitaro Tomiyama, Junro Seike, Kei Takahashi, Keizo Kaneko, Junta Imai, Hideki Katagiri
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Insulin like growth factor-1 (IGF-1) plays important roles in metabolic functions, especially in adulthood. Additionally, obese subjects are reportedly predisposed to having low absolute IGF-1 levels. However, the prevalence and clinical cha
Externí odkaz:
https://doaj.org/article/d316480ed876402eae1d68b175b6139b
Autor:
Masato Kohata, Junta Imai, Tomohito Izumi, Junpei Yamamoto, Yohei Kawana, Akira Endo, Hiroto Sugawara, Junro Seike, Haremaru Kubo, Hiroshi Komamura, Toshihiro Sato, Shinichiro Hosaka, Yuichiro Munakata, Yoichiro Asai, Shinjiro Kodama, Kei Takahashi, Keizo Kaneko, Hideki Katagiri
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 10, Pp 1666-1676 (2022)
ABSTRACT Aims/Introduction Whether basal β‐cell proliferation during adulthood is involved in maintaining sufficient β‐cell mass, and if so, the molecular mechanism(s) underlying basal β‐cell proliferation remain unclear. FoxM1 is a critical
Externí odkaz:
https://doaj.org/article/d05dbe7f5379427983242b019fd55228
Autor:
Satoko Hatayama, Shinjiro Kodama, Yohei Kawana, Sonoko Otake, Daiki Sato, Takahiro Horiuchi, Kei Takahashi, Keizo Kaneko, Junta Imai, Hideki Katagiri
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 8, Pp 1458-1460 (2022)
ABSTRACT Various immune‐related adverse events (irAEs), including fulminant type 1 diabetes (FT1D), are known to be associated with immune checkpoint inhibitors (ICIs). We experienced two lung adenocarcinoma cases who developed fulminant type 1 dia
Externí odkaz:
https://doaj.org/article/9665d9e385de4af5b054339ed518978f
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 7, Pp 1518-1520 (2022)
Recently, along with increasing use of immune checkpoint inhibitors such as nivolumab, the incidence of immune-related adverse events, including type 1 diabetes mellitus, has become a serious problem. We report a patient who had immune checkpoint inh
Externí odkaz:
https://doaj.org/article/237e8b5c89944ea5ae0771cb4b0213c8
Autor:
Tomohito Izumi, Junta Imai, Junpei Yamamoto, Yohei Kawana, Akira Endo, Hiroto Sugawara, Masato Kohata, Yoichiro Asai, Kei Takahashi, Shinjiro Kodama, Keizo Kaneko, Junhong Gao, Kenji Uno, Shojiro Sawada, Vladimir V. Kalinichenko, Yasushi Ishigaki, Tetsuya Yamada, Hideki Katagiri
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The mechanisms underlying the regenerative capacity of the liver are not fully understood. Here, the authors show that the acute regenerative response to liver injury in mice is regulated by the communication involving the vagus nerve, macrophages, a
Externí odkaz:
https://doaj.org/article/f719e1036e594ff69a5c540261de719c
Autor:
Shinichiro Hosaka, Tetsuya Yamada, Kei Takahashi, Takashi Dan, Keizo Kaneko, Shinjiro Kodama, Yoichiro Asai, Yuichiro Munakata, Akira Endo, Hiroto Sugawara, Yohei Kawana, Junpei Yamamoto, Tomohito Izumi, Shojiro Sawada, Junta Imai, Toshio Miyata, Hideki Katagiri
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Leptin resistance is an important mechanism underlying the development and maintenance of obesity and is thus regarded as a promising target of obesity treatment. Plasminogen activator inhibitor 1 (PAI-1), a physiological inhibitor of tissue-type and
Externí odkaz:
https://doaj.org/article/8c233b6245044c62997783ad18e1205c
Autor:
Junpei Yamamoto, Junta Imai, Tomohito Izumi, Hironori Takahashi, Yohei Kawana, Kei Takahashi, Shinjiro Kodama, Keizo Kaneko, Junhong Gao, Kenji Uno, Shojiro Sawada, Tomoichiro Asano, Vladimir V. Kalinichenko, Etsuo A. Susaki, Makoto Kanzaki, Hiroki R. Ueda, Yasushi Ishigaki, Tetsuya Yamada, Hideki Katagiri
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Neuronal signals, in particular those transmitted via the vagal nerve, regulate both β-cell function and proliferation. Here, Yamamoto et al. show that the forkhead box M1 pathway is required for vagal signal-mediated induction of β-cell proliferat
Externí odkaz:
https://doaj.org/article/aaeb1c2dd7e541f790c32e689f9722af
Autor:
Sohei Tsukita, Tetsuya Yamada, Kei Takahashi, Yuichiro Munakata, Shinichiro Hosaka, Hironobu Takahashi, Junhong Gao, Yuta Shirai, Shinjiro Kodama, Yoichiro Asai, Takashi Sugisawa, Yumiko Chiba, Keizo Kaneko, Kenji Uno, Shojiro Sawada, Junta Imai, Hideki Katagiri
Publikováno v:
EBioMedicine, Vol 15, Iss C, Pp 163-172 (2017)
Major symptoms of diabetes mellitus manifest, once pancreatic β-cell numbers have become inadequate. Although natural regeneration of β-cells after injury is very limited, bone marrow (BM) transplantation (BMT) promotes their regeneration through u
Externí odkaz:
https://doaj.org/article/b378414ea3c8407c863d829ecbcd8641