Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Shinjiro, Hino"'
Autor:
Yoshiki Hayashi, Soshiro Kashio, Kazutoshi Murotomi, Shinjiro Hino, Woojin Kang, Kenji Miyado, Mitsuyoshi Nakao, Masayuki Miura, Satoru Kobayashi, Masakazu Namihira
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Tissue aging is a major cause of aging-related disabilities and a shortened life span. Understanding how tissue aging progresses and identifying the factors underlying tissue aging are crucial; however, the mechanism of tissue aging is not f
Externí odkaz:
https://doaj.org/article/05e309c3bbee4546af40f1bf690393d7
Autor:
Hiromasa Kato, Hiroshi Watanabe, Tadashi Imafuku, Nanaka Arimura, Issei Fujita, Isamu Noguchi, Shoma Tanaka, Takehiro Nakano, Kai Tokumaru, Yuki Enoki, Hitoshi Maeda, Shinjiro Hino, Motoko Tanaka, Kazutaka Matsushita, Masafumi Fukagawa, Toru Maruyama
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 1832-1847 (2021)
Abstract Background Sarcopenia with chronic kidney disease (CKD) progression is associated with life prognosis. Oxidative stress has attracted interest as a trigger for causing CKD‐related muscular atrophy. Advanced oxidation protein products (AOPP
Externí odkaz:
https://doaj.org/article/8e2b4ae67b8649ef93f2737fd499cb41
Autor:
Hirotaka Araki, Shinjiro Hino, Kotaro Anan, Kanji Kuribayashi, Kan Etoh, Daiki Seko, Ryuta Takase, Kensaku Kohrogi, Yuko Hino, Yusuke Ono, Eiichi Araki, Mitsuyoshi Nakao
Publikováno v:
eLife, Vol 12 (2023)
Skeletal muscle exhibits remarkable plasticity in response to environmental cues, with stress-dependent effects on the fast-twitch and slow-twitch fibers. Although stress-induced gene expression underlies environmental adaptation, it is unclear how t
Externí odkaz:
https://doaj.org/article/7d544e7157754546a4cf4b608bded09c
Autor:
Takuro Horii, Sumiyo Morita, Shinjiro Hino, Mika Kimura, Yuko Hino, Hiroshi Kogo, Mitsuyoshi Nakao, Izuho Hatada
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract Background Epigenetic modifications, including DNA methylation, play an important role in gene silencing and genome stability. Consequently, epigenetic dysregulation can cause several diseases, such as cancer, obesity, diabetes, autism, and
Externí odkaz:
https://doaj.org/article/ddbaf52b3f00427c813f81dfb8ab45b8
Autor:
Ubonrat Thamrongwaranggoon, Kanji Kuribayashi, Hirotaka Araki, Yuko Hino, Tomoaki Koga, Wunchana Seubwai, Sopit Wongkham, Mitsuyoshi Nakao, Shinjiro Hino
Publikováno v:
Cancer Science. 114:1541-1555
High glycolytic activity of cancer cells leads to lactic acidosis (LA) in the tumor microenvironment. LA is not merely a consequence of metabolic activities, but also has functional roles in metabolic reprogramming and cancer progression. Cholangioca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f08bc8e1fe2028435f697b03939c498
https://doi.org/10.1111/cas.15699
https://doi.org/10.1111/cas.15699
Autor:
Hiroshi Tanaka, Shin-ichiro Takebayashi, Akihisa Sakamoto, Tomoka Igata, Yuko Nakatsu, Noriko Saitoh, Shinjiro Hino, Mitsuyoshi Nakao
Publikováno v:
Cell Reports, Vol 18, Iss 9, Pp 2148-2161 (2017)
Summary: Cellular senescence is an irreversible growth arrest that contributes to development, tumor suppression, and age-related conditions. Senescent cells show active metabolism compared with proliferating cells, but the underlying mechanisms rema
Externí odkaz:
https://doaj.org/article/19dbff3eeaf547fc9ad3a9db67131595
Autor:
Tsuyoshi Osawa, Teppei Shimamura, Kyoko Saito, Yoko Hasegawa, Naoko Ishii, Miyuki Nishida, Ritsuko Ando, Ayano Kondo, Muyassar Anwar, Rika Tsuchida, Shinjiro Hino, Akihisa Sakamoto, Kaori Igarashi, Kaori Saitoh, Keiko Kato, Keiko Endo, Shotaro Yamano, Yasuharu Kanki, Yoshihiro Matsumura, Takashi Minami, Toshiya Tanaka, Motonobu Anai, Youichiro Wada, Hideki Wanibuchi, Mitsuhiro Hayashi, Akinobu Hamada, Masayuki Yoshida, Shinichi Yachida, Mitsuyoshi Nakao, Juro Sakai, Hiroyuki Aburatani, Masabumi Shibuya, Kentaro Hanada, Satoru Miyano, Tomoyoshi Soga, Tatsuhiko Kodama
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 89-103.e7 (2019)
Summary: Tolerance to severe tumor microenvironments, including hypoxia and nutrient starvation, is a common feature of aggressive cancer cells and can be targeted. However, metabolic alterations that support cancer cells upon nutrient starvation are
Externí odkaz:
https://doaj.org/article/c34c33e130784dc786b3ca3e8ed731d1
Autor:
Masaya Yamazaki, Shinjiro Hino, Shingo Usuki, Yoshihiro Miyazaki, Tatsuya Oda, Mitsuyoshi Nakao, Takaaki Ito, Kazuya Yamagata
Publikováno v:
The EMBO Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f56aaab4378e8510188a35547e919b7
https://doi.org/10.15252/embj.2022112614
https://doi.org/10.15252/embj.2022112614
Autor:
Jun Qi, Teru Hideshima, Kenneth C. Anderson, Adam D. Durbin, Udo Oppermann, Javed Khan, Shannon Lauberth, Takashi Minami, Mitsuyoshi Nakao, Sumio Ohtsuki, Masao Matsuoka, Nikhil C. Munshi, Yu-Tzu Tai, Mehmet K. Samur, Yawara Kawano, Shingo Usuki, Shinjiro Hino, Yong Kim, Virangika K. Wimalasena, Catrine Johansson, Takeshi Masuda, Chengkui Pei, Deyao Li, Xiaofeng Zhang, Keiji Kurata, Daisuke Ogiya, Berkley E. Gryder, Tingjian Wang, Paul M.C. Park, Hiroto Ohguchi
Supplementary Table 1 listed the genes upregulated and downregulated after treatment with JQKD82 in MM1S cells for 48 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e84aa2be7384efbe6686f30a58ba273
https://doi.org/10.1158/2643-3230.22543984
https://doi.org/10.1158/2643-3230.22543984
Autor:
Jun Qi, Teru Hideshima, Kenneth C. Anderson, Adam D. Durbin, Udo Oppermann, Javed Khan, Shannon Lauberth, Takashi Minami, Mitsuyoshi Nakao, Sumio Ohtsuki, Masao Matsuoka, Nikhil C. Munshi, Yu-Tzu Tai, Mehmet K. Samur, Yawara Kawano, Shingo Usuki, Shinjiro Hino, Yong Kim, Virangika K. Wimalasena, Catrine Johansson, Takeshi Masuda, Chengkui Pei, Deyao Li, Xiaofeng Zhang, Keiji Kurata, Daisuke Ogiya, Berkley E. Gryder, Tingjian Wang, Paul M.C. Park, Hiroto Ohguchi
Supplementary Figure S1 shows that higher KDM5A expression is associated with poor prognosis in MM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e704237c08b6a6e879e0516bbaaefff6
https://doi.org/10.1158/2643-3230.22544005.v1
https://doi.org/10.1158/2643-3230.22544005.v1