Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Shinji Uyeno"'
Publikováno v:
Mechanisms of Ageing and Development. 110:37-48
In an attempt to understand the molecular mechanisms of age-dependent degenerative alteration in human periodontal tissues, we examined mRNA level and DNA methylation of collagen alpha1(I) gene. Using healthy periodontal ligament tissues from humans
Autor:
Hiromitsu Yamakawa, Akihiko Suzuki, Shigefumi Fujimura, Shinji Uyeno, Masami Sato, Kazuhiko Orikasa, Akira Sakurada, Noriaki Ohuchi, Akira Horii, Tetsuya Ono
Publikováno v:
Japanese Journal of Cancer Research : Gann
In the present study, we searched for genetic alterations of the entire coding region of PTEN/MMACl, a recently isolated candidate tumor suppressor gene, in 178 specimens from Japanese patients with various malignant tumors by the polymerase chain re
Autor:
Eun-Kyoung Choi, Naoshi Nishida, Yong-Sun Kim, Yasuhiro Aoki, Shinji Uyeno, Kaoru Sagisaka, Masayuki Nata, T. Okumoto, Tetsuya Ono, Yoshihiro Fukuda, Kazuwa Nakao, S. Fujimura, Takashi Yoshimoto
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 354:123-128
The state of DNA methylation in the c-fos gene was examined in human livers of different ages, cirrhosis and hepatocellular carcinoma. The degree of methylation in the intron 1 to exon 4 region increased with age, whereas all of the 10 cirrhosis samp
Autor:
Hironobu Sasano, Kaoru Sagisaka, Takashi Yoshimoto, Jun Ichiro Komura, Hiroshi Nakura, Yasuhiro Aoki, Hiromu Sakurai, Masayuki Nata, Riichi Tawa, Shinji Uyeno, Tetsuya Ono, Takamasa Kayama
Publikováno v:
Molecular carcinogenesis. 16(2)
In an attempt to find a common DNA alteration occurring in human glioma, we examined DNA methylation in 34 gliomas of various pathological grades and compared them with those in normal cerebral subcortex DNA. The total methylated cytosine levels in t