Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Shinji Toki"'
Autor:
Jacqueline-Yvonne Cephus, Matthew T. Stier, Hubaida Fuseini, Jeffrey A. Yung, Shinji Toki, Melissa H. Bloodworth, Weisong Zhou, Kasia Goleniewska, Jian Zhang, Sarah L. Garon, Robert G. Hamilton, Vasiliy V. Poloshukin, Kelli L. Boyd, R. Stokes Peebles, Jr., Dawn C. Newcomb
Publikováno v:
Cell Reports, Vol 21, Iss 9, Pp 2487-2499 (2017)
Sex hormones regulate many autoimmune and inflammatory diseases, including asthma. As adults, asthma prevalence is 2-fold greater in women compared to men. The number of group 2 innate lymphoid cells (ILC2) is increased in patients with asthma, and w
Externí odkaz:
https://doaj.org/article/87fabe7a1e54432baf5024d79aed6767
Autor:
Weisong Zhou, Dustin R Dowell, Matthew M Huckabee, Dawn C Newcomb, Madison G Boswell, Kasia Goleniewska, Matthew T Lotz, Shinji Toki, Huiyong Yin, Songyi Yao, Chandramohan Natarajan, Pingsheng Wu, Subramaniam Sriram, Richard M Breyer, Garret A Fitzgerald, R Stokes Peebles
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e33518 (2012)
Prostaglandin I(2) (PGI(2)), a lipid mediator currently used in treatment of human disease, is a critical regulator of adaptive immune responses. Although PGI(2) signaling suppressed Th1 and Th2 immune responses, the role of PGI(2) in Th17 differenti
Externí odkaz:
https://doaj.org/article/d774297d24ed40ff8729d84c5dc26fd2
Autor:
Shinji Toki, Jian Zhang, Richard L. Printz, Dawn C. Newcomb, Katherine N. Cahill, Kevin D. Niswender, R. Stokes Peebles
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyREFERENCES.
Autor:
Shinji Toki
Shinji Toki1, Jian Zhang1, Richard L. Printz2, Dawn C. Newcomb1,3, Katherine N. Cahill2, Kevin D. Niswender3,4,5, R. Stokes Peebles Jr. 1,2,5 1 Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nash
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337a2a9bde68078a2f0e5fb07e756794
Autor:
R. Stokes Peebles, Kevin D. Niswender, Dawn C. Newcomb, Kelli L. Boyd, Richard L. Printz, Katherine N. Cahill, Shinji Toki
Publikováno v:
Allergy
Background Obesity is a risk factor for the development of asthma. However, pharmacologic therapeutic strategies that specifically target obese asthmatics have not been identified. We hypothesize that glucagon‐like peptide‐1 receptor agonist (GLP
Autor:
Brandon Baer, Nathan D. Putz, Dustin Gibson, Shinji Toki, Stokes Peebles, Katherine N. Cahill, Julie A. Bastarache
Publikováno v:
The FASEB Journal. 36
Autor:
Kelli L. Boyd, Kasia Goleniewska, Weisong Zhou, Shinji Toki, Dawn C. Newcomb, Pingsheng Wu, Hirohito Kita, R. Stokes Peebles, Jian Zhang, Allison E. Norlander
Publikováno v:
The Journal of Immunology. 205:1157-1166
The cyclooxygenase (COX) metabolic pathway regulates immune responses and inflammation. The effect of the COX pathway on innate pulmonary inflammation induced by protease-containing fungal allergens, such as Alternaria alternata, is not fully defined
Autor:
Dawn C. Newcomb, K. Nichole Maloney, Eric P. Skaar, Walter J. Chazin, Kelli L. Boyd, R. Stokes Peebles, Lauren D. Palmer, C. Noel Maxwell, Shinji Toki, A. Kasia Goleniewska
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 61:459-468
Calprotectin is a heterodimer of the proteins S100A8 and S100A9, and it is an abundant innate immune protein associated with inflammation. In humans, calprotectin transcription and protein abundance are associated with asthma and disease severity. Ho
Autor:
Lisa M. Rogers, Vasiliy V. Polosukhin, R. Stokes Peebles, Weisong Zhou, Shinji Toki, Jacqueline-Yvonne Cephus, David M. Aronoff, Zachary J Ceneviva, Dawn C. Newcomb, Janey Wang, Melissa H. Bloodworth, Lisa Bastarache, Nowrin U. Chowdhury, Jian Zhang, Vivek D. Gandhi, Kelli L. Boyd, Louis-Marie Charbonnier, Talal A. Chatila, Allison E. Norlander
Publikováno v:
J Clin Invest
T regulatory cells (Treg) restrain both the innate and adaptive immune systems to maintain homeostasis. Allergic airway inflammation, characterized by a type 2 (Th2) response that results from a breakdown of tolerance to innocuous environmental antig
Autor:
Weisong Zhou, Jian Zhang, Nowrin U Chowdhury, Allison E Norlander, Shinji Toki, Dawn C Newcomb, R Stokes Peebles
Publikováno v:
The Journal of Immunology. 208:169.05-169.05
Prostaglandin I2 (PGI2) is a lipid molecule produced in the cyclooxygenase (COX) metabolic pathway and regulates T cell function and inflammation. We have previously shown that PGI2 inhibited type 2 cytokine production by Th2 cells in vitro and in vi