Zobrazeno 1 - 10
of 402
pro vyhledávání: '"Shinji Saitoh"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Somatic mutations in MYCN have been identified across various tumors, playing pivotal roles in tumorigenesis, tumor progression, and unfavorable prognoses. Despite its established notoriety as an oncogenic driver, there is a growing interest in explo
Externí odkaz:
https://doaj.org/article/bc8e53e220204ef6910f36236a31c184
Autor:
Hana Milena Fujimoto, Masanori Fujimoto, Takahiro Sugiura, Shigeharu Nakane, Yasuhiro Wakano, Emi Sato, Hironori Oshita, Yasuko Togawa, Mari Sugimoto, Takenori Kato, Kazushi Yasuda, Kanji Muramatsu, Shinji Saitoh
Publikováno v:
Human Genome Variation, Vol 10, Iss 1, Pp 1-4 (2023)
Abstract Striated muscle preferentially expressed protein kinase (SPEG) variants have been reported to cause centronuclear myopathy associated with cardiac diseases. The severity of skeletal muscle symptoms and cardiac symptoms are presumably related
Externí odkaz:
https://doaj.org/article/d7182805ebe743dfb5db97479f0f5f34
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Both iron excess and deficiency are deleterious to cellular and organ homeostasis. Serum ferritin levels serve as a biomarker of iron storage; however, their distribution and determinants in sick newborn infants remain unclear. This study ai
Externí odkaz:
https://doaj.org/article/27eafceeace440718ddd0d6068038e12
Autor:
Satoko Fukaya, Sachiko Iwata, Kennosuke Tsuda, Akiko Hirose, Masahiro Kinoshita, Shinji Saitoh, Osuke Iwata
Publikováno v:
Biosensors, Vol 14, Iss 4, p 209 (2024)
Subtle changes in body temperature affect the outcomes of ill newborns. However, the temperature profile of neonatal brains remains largely unknown. In open-cot care, increased cerebral perfusion is correlated with higher superficial brain temperatur
Externí odkaz:
https://doaj.org/article/3ff08c5d9f66497fb44ef891c4b9b08a
Autor:
Midori Obayashi, Sachiko Iwata, Tomoya Okuda, Ichita Mori, Shigeharu Nakane, Yasuko Togawa, Mari Sugimoto, Takao Togawa, Kanji Muramatsu, Shinji Saitoh, Takahiro Sugiura, Osuke Iwata
Publikováno v:
Nutrients, Vol 16, Iss 4, p 476 (2024)
Early enteral nutrition using reliable biomarkers of intestinal function must be established to improve neurodevelopmental outcomes in very low birth weight infants (VLBWIs). Serum citrulline levels reflect the intestinal function in adults. To eluci
Externí odkaz:
https://doaj.org/article/39eb20ceb1834418a213865c5c5e6f0a
Autor:
Akiko Nakaoka, Takayasu Nomura, Kazuyoshi Ozeki, Tomotaka Suzuki, Shigeru Kusumoto, Shinsuke Iida, Shinji Saitoh
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 19, Iss 1, Pp 1-4 (2023)
Abstract Background Cases of food allergy after hematopoietic stem cell and solid organ transplantation in previously nonallergic transplant recipients were reported as transplant-acquired food allergy (TAFA), but information about its long-term outc
Externí odkaz:
https://doaj.org/article/c3305fafe5e5421380f46cb5233a64ea
Autor:
Yosuke Nishio, Kohji Kato, Frederic Tran Mau-Them, Hiroshi Futagawa, Chloé Quélin, Saori Masuda, Antonio Vitobello, Shiomi Otsuji, Hossam H. Shawki, Hisashi Oishi, Christel Thauvin-Robinet, Toshiki Takenouchi, Kenjiro Kosaki, Yoshiyuki Takahashi, Shinji Saitoh
Publikováno v:
HGG Advances, Vol 4, Iss 4, Pp 100238- (2023)
Summary: MYCN, a member of the MYC proto-oncogene family, regulates cell growth and proliferation. Somatic mutations of MYCN are identified in various tumors, and germline loss-of-function variants are responsible for Feingold syndrome, characterized
Externí odkaz:
https://doaj.org/article/500afd5a9bde413c8c9a8ccf0d6652d9
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1656 (2023)
Despite advances in treatment options, such as corticosteroid administration and less invasive respiratory support, bronchopulmonary dysplasia (BPD) remains an important prognostic factor in preterm infants. We previously reported that furin regulate
Externí odkaz:
https://doaj.org/article/73294fa0c39946b599952c93fba3720c
Autor:
Sachiko Iwata, Reiji Katayama, Kennosuke Tsuda, Yung‐Chieh Lin, Tsuyoshi Kurata, Masahiro Kinoshita, Koya Kawase, Takenori Kato, Shin Kato, Tadashi Hisano, Motoki Oda, Etsuko Ohmae, Sachio Takashima, Yuko Araki, Shinji Saitoh, Osuke Iwata
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 9, Pp 1417-1427 (2022)
Abstract Objective MRI provides useful information regarding brain maturation and injury in newborn infants. However, MRI studies are generally restricted during acute phase, resulting in uncertainty around upstream clinical events responsible for su
Externí odkaz:
https://doaj.org/article/47a8ba50a619484e95f15b375d88efe4
Autor:
Kotaro Narita, Hideki Muramatsu, Satoshi Narumi, Yuji Nakamura, Yusuke Okuno, Kyogo Suzuki, Motoharu Hamada, Naoya Yamaguchi, Atsushi Suzuki, Yosuke Nishio, Anna Shiraki, Ayako Yamamori, Yusuke Tsumura, Fumi Sawamura, Masahiro Kawaguchi, Manabu Wakamatsu, Shinsuke Kataoka, Kohji Kato, Hideyuki Asada, Tetsuo Kubota, Yukako Muramatsu, Hiroyuki Kidokoro, Jun Natsume, Seiji Mizuno, Tomohiko Nakata, Hidehito Inagaki, Naoko Ishihara, Takahiro Yonekawa, Akihisa Okumura, Tomoo Ogi, Seiji Kojima, Tadashi Kaname, Tomonobu Hasegawa, Shinji Saitoh, Yoshiyuki Takahashi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Recently, whole-exome sequencing (WES) has been used for genetic diagnoses of patients who remain otherwise undiagnosed. WES was performed in 177 Japanese patients with undiagnosed conditions who were referred to the Tokai regional branch of
Externí odkaz:
https://doaj.org/article/74fa295534ea4b28abbb48acc9d5d11c