Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Shinji Oie"'
Autor:
Michihiko Kuwano, Takashi Yanagawa, Mayumi Ono, Masazumi Tsuneyoshi, Suminori Kono, Nao Suzuki, Shinji Oie, Yuji Basaki, Yoshihiro Ohishi, Ken-ichi Taguchi, Satoshi Hattori, Yoshinao Oda, Daisuke Aoki
Supplementary Data from Overexpression of Class III β-Tubulin Predicts Good Response to Taxane-Based Chemotherapy in Ovarian Clear Cell Adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36af5ff0ed27b6958f0d7aa103c1941d
https://doi.org/10.1158/1078-0432.22440138.v1
https://doi.org/10.1158/1078-0432.22440138.v1
Autor:
Michihiko Kuwano, Takashi Yanagawa, Mayumi Ono, Masazumi Tsuneyoshi, Suminori Kono, Nao Suzuki, Shinji Oie, Yuji Basaki, Yoshihiro Ohishi, Ken-ichi Taguchi, Satoshi Hattori, Yoshinao Oda, Daisuke Aoki
Purpose: Of the various microtubule-associated molecules, β-tubulin III has been reported to be closely associated with the therapeutic efficacy of taxane-based chemotherapy against ovarian cancer. Stathmin and microtubule-associated protein 4 (MAP4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd0467054d3f7ac1df769a035120ffd
https://doi.org/10.1158/1078-0432.c.6517509.v1
https://doi.org/10.1158/1078-0432.c.6517509.v1
Autor:
Tsutomu Kobayashi, Etsuko Sakamoto, Masafumi Kumazaki, Taro Isobe, Shinichi Hasako, Jun Akiba, Takuji Torimura, Hiraku Itadani, Akiko Sumi, Hironori Kusano, Shinji Mizuarai, Shinji Oie, Junya Kizaki, Yoshito Akagi, Sachiko Ogasawara, Makiko Yasumoto, Hirohisa Yano
Publikováno v:
Cancer Medicine
The prognosis of patients with Borrmann type IV gastric cancer (Type IV) is extremely poor. Thus, there is an urgent need to elucidate the molecular mechanisms underlying the oncogenesis of Type IV and to identify new therapeutic targets. Although pr
Autor:
Nao Suzuki, Shinji Oie, Sachiko Ezawa, Yuko Hasegawa, Hiroshi Matsumoto, Kimiko Orikawa, Ki Ichi Miyashita, Daisuke Aoki, Nobuyuki Susumu, Atsushi Higashiguchi
Publikováno v:
Human Cell. 18:147-155
Among various types of surface epithelial ovarian carcinoma, clear cell adenocarcinoma often has a particularly poor prognosis even when diagnosed in stage I. It is resistant to existing anticancer drugs and appears to have different biological prope
Autor:
Tatsuzo Oka, Etsuko Sakamoto, Shinji Oie, Takashi Kobunai, Masakazu Fukushima, Toshinori Oka, Yoshihiro Okayama, Sayaka Tsukioka, Hiroaki Tsujimoto, Kazuki Sakamoto, Yoshikazu Sugimoto
Publikováno v:
Biochemical and Biophysical Research Communications. 365:801-807
Although 5-fluorouracil (5-FU) plus leucovorin (LV) is a standard chemotherapy regimen for colorectal cancer, the factors that determine the LV-mediated enhancement of the antitumor activity of 5-FU have remained unknown. We investigated the roles of
Autor:
Takashi Kobunai, Masakazu Fukushima, Tatsuzo Oka, Shinji Oie, Hideki Nagase, Etsuko Sakamoto, Toshinori Oka
Publikováno v:
Biochemical and Biophysical Research Communications. 363:216-222
Although the intratumoral expression levels of thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) are known to affect the antitumor activity of 5-fluorouracil (5-FU), the importance of orotate phosphoribosyltransferase (OPRT) has rem
Autor:
Keitaro Kuratomi, Masamichi Kojiro, Yuji Basaki, Seiya Momosaki, Fukuko Moriya, Michihiko Kuwano, Naoyo Nishida, Jun Akiba, Shinji Oie, Sakiko Kojiro, Suguru Fukahori, Hirohisa Yano, Hironori Ishizaki, Sachiko Ogasawara
Publikováno v:
Journal of Interferon & Cytokine Research. 27:231-238
We investigated the effects of pegylated (PEG)-IFN-alpha2b on alpha-fetoprotein (AFP) expression as demonstrated by protein and mRNA levels in six human hepatocellular carcinoma (HCC) cell lines. The number of KIM-1 cells in culture with PEG-IFN-alph
Autor:
Etsuko Sakamoto, Yuhei Kitasato, Yoshinobu Okabe, Shinji Mizuarai, Shinji Oie, Yoshiki Naito, Masafumi Yasunaga, Hiroto Fukushima, Hirohisa Yano, Sachiko Ogasawara, Hiroyuki Horiuchi, Jun Akiba, Makiko Yasumoto, Yusuke Ishida, Hiraku Itadani, Masamichi Nakayama
Publikováno v:
Molecular Cancer
Background Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive neoplastic diseases, associated with a remarkably poor prognosis. However, the molecular mechanisms underlying the development of PDAC remain elusive. The aim of this st
Autor:
Masamichi Kojiro, Shinichi Aishima, Michio Sata, Abbas Fotovati, Yuji Basaki, Yoshinao Oda, Mayumi Ono, Fumihito Hosoi, Yunosuke Nishihara, Kenichi Taguchi, Michihiko Kuwano, Masazumi Tsuneyoshi, Shinji Oie, Akinobu Taketomi, Takato Ueno, Hirohisa Yano, Yousuke Kuroda, Yoshihiko Maehara, Yuichiro Maruyama
Publikováno v:
Cancer Science. 97:1182-1190
Insulin-like growth factor binding protein-3 (IGFBP-3) modulates cell proliferation of various cancer cell types. However, it remains unclear how IGF-IGFBP-3-signaling is involved in growth and progression of hepatocellular carcinoma (HCC). The aim o
Autor:
Tatsu Shimoyama, Michihiko Kuwano, Abbas Fotovati, Yuji Basaki, Hiroto Izumi, Kimitoshi Kohno, Yuichiro Maruyama, Mayumi Ono, Kazuto Nishio, Shinji Oie, Kazuko Sakai, Fumihito Hosoi, Yoshinao Oda
Publikováno v:
Oncogene. 26:2736-2746
Y-box-binding protein 1 (YB-1), which is a member of the DNA-binding protein family containing a cold-shock domain, has pleiotropic functions in response to various environmental stimuli. As we previously showed that YB-1 is a global marker of multid