Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Shinji Ohmachi"'
Autor:
Makoto Todo, Tomiyoshi Aoki, Tetsuo Asaki, Shinji Ohmachi, Kenji Kuwabara, Kohji Murakami, Yukiteru Sugiyama, Taisuke Hamamoto
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:2128-2132
A new series of 1,3-dioxane-2-carboxylic acid derivatives was synthesized and evaluated for agonist activity at human peroxisome proliferator-activated receptor (PPAR) subtypes. Structure-activity relationship studies led to the identification of 2-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa343fd698e8684a49e6f0eb0a4688c
https://doi.org/10.1016/j.bmcl.2008.01.086
https://doi.org/10.1016/j.bmcl.2008.01.086
Autor:
Makoto Todo, Yukiteru Sugiyama, Tomiyoshi Aoki, Shinji Ohmachi, Kohji Murakami, Tetsuo Asaki, Kenji Kuwabara, Taisuke Hamamoto
Publikováno v:
Bioorganicmedicinal chemistry. 16(2)
A series of 1,3-dioxane carboxylic acid derivatives was synthesized and evaluated for human PPAR transactivation activity. Structure-activity relationships on the phenyloxazole moiety of the lead compound 3 revealed that the introduction of small hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2866d3073594659655aca56a8f2dccf
https://pubmed.ncbi.nlm.nih.gov/17964792
https://pubmed.ncbi.nlm.nih.gov/17964792