Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Shinji Nakaoka"'
Autor:
Kosaku Kitagawa, Kwang Su Kim, Masashi Iwamoto, Sanae Hayashi, Hyeongki Park, Takara Nishiyama, Naotoshi Nakamura, Yasuhisa Fujita, Shinji Nakaoka, Kazuyuki Aihara, Alan S Perelson, Lena Allweiss, Maura Dandri, Koichi Watashi, Yasuhito Tanaka, Shingo Iwami
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 3, p e1011238 (2024)
Chronic infection with hepatitis B virus (HBV) is caused by the persistence of closed circular DNA (cccDNA) in the nucleus of infected hepatocytes. Despite available therapeutic anti-HBV agents, eliminating the cccDNA remains challenging. Thus, quant
Externí odkaz:
https://doaj.org/article/106f0b67c3384d5189bfd286b6982a62
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-4 (2023)
Abstract Objective The purpose of this data set is to investigate differences in RNA-Seq transcriptome profiles between Acarapis woodi-infested and uninfested Japanese honey bees (Apis cerana japonica). The data set is strengthened by data collected
Externí odkaz:
https://doaj.org/article/24b98727186246e8b597d421cab8e4c6
Autor:
Kazuhito Miura, Yutaka Watanabe, Haruhisa Baba, Kimiya Ozaki, Takae Matsushita, Miyako Kondoh, Kazutaka Okada, Shinji Nakaoka, Katsuhiko Ogasawara, Teppei Suzuki, Hiroshi Saito, Takashi Kimura, Akiko Tamakoshi, Yutaka Yamazaki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract This study examined the association between coronavirus disease 2019 (COVID-19)-related stress, exercise habits, and oral health-related quality of life (OHRQoL) in a sample of 215 community-dwelling older adults in Japan (57 men, 158 women;
Externí odkaz:
https://doaj.org/article/b106c79d69654b749fa332b4494fa0ae
Autor:
Yuji Okamoto, Mitsuhito Hirano, Kai Morino, Masashi K. Kajita, Shinji Nakaoka, Mayuko Tsuda, Kei-ji Sugimoto, Shigehisa Tamaki, Junichi Hisatake, Hisayuki Yokoyama, Tadahiko Igarashi, Atsushi Shinagawa, Takeaki Sugawara, Satoru Hara, Kazuhisa Fujikawa, Seiichi Shimizu, Toshiaki Yujiri, Hisashi Wakita, Kaichi Nishiwaki, Arinobu Tojo, Kazuyuki Aihara
Publikováno v:
npj Systems Biology and Applications, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Chronic myeloid leukemia (CML) is a myeloproliferative disorder caused by the BCR-ABL1 tyrosine kinase. Although ABL1-specific tyrosine kinase inhibitors (TKIs) including nilotinib have dramatically improved the prognosis of patients with CM
Externí odkaz:
https://doaj.org/article/58f4e055c3eb45ed81510406b1170155
Publikováno v:
Frontiers in Food Science and Technology, Vol 2 (2022)
Although bacterial population behavior has been investigated in a variety of foods in the past 40 years, it is difficult to obtain desired information from the mere juxtaposition of experimental data. We predicted the changes in the number of bacteri
Externí odkaz:
https://doaj.org/article/88c9c1a9777b47e1a115ba6862459744
Autor:
Teruo Akuta, Daisuke Minegishi, Nobuhide Kido, Keitaro Imaizumi, Shinji Nakaoka, Shin-Ichiro Tachibana, Kenji Hikosaka, Fumi Hori, Masataka, Nakagawa, Chiaki Sakuma, Yuki Oouchi, Yu Nakajima, Sohei Tanaka, Tomoko Omiya, Kouki Morikaku, Minori Kawahara, Yoshifumi Tada, Hiroshi Tarui, Takafumi Ueda, Takane Kikuchi-Ueda, Yasuo Ono
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Scabies is a highly contagious skin disease caused by the mite Sarcoptes scabiei that affects many mammals. However, the sensitivity of traditional tests for scabies diagnosis in humans is less than 50%. To simplify the diagnosis of scabies,
Externí odkaz:
https://doaj.org/article/4b1a1fd9236441328e4c8ffb0f0a9788
Autor:
Ryuichi Kumata, Shoya Iwanami, Katrina B. Mar, Yusuke Kakizoe, Naoko Misawa, Shinji Nakaoka, Yoshio Koyanagi, Alan S. Perelson, John W. Schoggins, Shingo Iwami, Kei Sato
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 4 (2022)
In HIV-1-infected individuals, transmitted/founder (TF) virus contributes to establish new infection and expands during the acute phase of infection, while chronic control (CC) virus emerges during the chronic phase of infection. TF viruses are more
Externí odkaz:
https://doaj.org/article/c615a55f452444d192ab0e7fc82364cb
Autor:
Yosuke Komatsu, Daiki Kumakura, Namiko Seto, Hirohisa Izumi, Yasuhiro Takeda, Yuki Ohnishi, Shinji Nakaoka, Tomoyasu Aizawa
Publikováno v:
Frontiers in Nutrition, Vol 8 (2022)
Background: The gut microbiome and fecal metabolites of breastfed infants changes during lactation, and are influenced by breast milk components. This study aimed to investigate dynamic associations of milk components with the infant gut microbiome a
Externí odkaz:
https://doaj.org/article/4778e8e493ef4cbfaefb3f9097652bdd
Autor:
Shoya Iwanami, Keisuke Ejima, Kwang Su Kim, Koji Noshita, Yasuhisa Fujita, Taiga Miyazaki, Shigeru Kohno, Yoshitsugu Miyazaki, Shimpei Morimoto, Shinji Nakaoka, Yoshiki Koizumi, Yusuke Asai, Kazuyuki Aihara, Koichi Watashi, Robin N Thompson, Kenji Shibuya, Katsuhito Fujiu, Alan S Perelson, Shingo Iwami, Takaji Wakita
Publikováno v:
PLoS Medicine, Vol 18, Iss 7, p e1003660 (2021)
BackgroundDevelopment of an effective antiviral drug for Coronavirus Disease 2019 (COVID-19) is a global health priority. Although several candidate drugs have been identified through in vitro and in vivo models, consistent and compelling evidence fr
Externí odkaz:
https://doaj.org/article/516b82537a63450ab8a2bac11a255a96
Publikováno v:
Mathematical Biosciences and Engineering, Vol 16, Iss 4, Pp 2219-2232 (2019)
Calculation of final size of an epidemic model offers a useful estimation for the impact of an epidemic. Despite its usefulness, the majority of practical applications focuses on the classical Kermack McKendrick model for final size calculation. Esti
Externí odkaz:
https://doaj.org/article/015cde3031e6486cb8c8cf05fef3896b