Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Shinji Komazaki"'
Autor:
Atsuhiko Ichimura, Yuu Miyazaki, Hiroki Nagatomo, Takaaki Kawabe, Nobuhisa Nakajima, Ga Eun Kim, Masato Tomizawa, Naoki Okamoto, Shinji Komazaki, Sho Kakizawa, Miyuki Nishi, Hiroshi Takeshima
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-11 (2023)
Abstract TRIC-A and TRIC-B proteins form homotrimeric cation-permeable channels in the endoplasmic reticulum (ER) and nuclear membranes and are thought to contribute to counterionic flux coupled with store Ca2+ release in various cell types. Serious
Externí odkaz:
https://doaj.org/article/baa927d664844ef1b3966151148b0648
Autor:
Megumi Kowno, Kanako Watanabe-Susaki, Hisako Ishimine, Shinji Komazaki, Kei Enomoto, Yasuhiro Seki, Ying Ying Wang, Yohei Ishigaki, Naoto Ninomiya, Taka-aki K Noguchi, Yuko Kokubu, Keigoh Ohnishi, Yoshiro Nakajima, Kaoru Kato, Atsushi Intoh, Hitomi Takada, Norio Yamakawa, Pi-Chao Wang, Makoto Asashima, Akira Kurisaki
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e81552 (2014)
BackgroundThe pluripotent state of embryonic stem (ES) cells is controlled by a network of specific transcription factors. Recent studies also suggested the significant contribution of mitochondria on the regulation of pluripotent stem cells. However
Externí odkaz:
https://doaj.org/article/52c23efd6a4e47d5af04501a320884f9
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49862 (2012)
There is substantial evidence indicating that disruption of Ca(2+) homeostasis and activation of cytosolic proteases play a key role in the pathogenesis and progression of Duchenne Muscular Dystrophy (DMD). However, the exact nature of the Ca(2+) der
Externí odkaz:
https://doaj.org/article/16c3d516b4db4962b8cade199f705844
Autor:
Andoria Tjondrokoesoemo, Ki Ho Park, Christopher Ferrante, Shinji Komazaki, Sebastian Lesniak, Marco Brotto, Jae-Kyun Ko, Jingsong Zhou, Noah Weisleder, Jianjie Ma
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25740 (2011)
Efficient intracellular Ca²⁺ ([Ca²⁺]i) homeostasis in skeletal muscle requires intact triad junctional complexes comprised of t-tubule invaginations of plasma membrane and terminal cisternae of sarcoplasmic reticulum. Bin1 consists of a special
Externí odkaz:
https://doaj.org/article/5d73be6573ac40e08c39cbdb8809f3b9
Autor:
Atsuhiko Ichimura, Yuu Miyazaki, Hiroki Nagatomo, Masato Tomizawa, Takaaki Kawabe, Nobuhisa Nakajima, Naoki Okamoto, Shinji Komazaki, Sho Kakizawa, Miyuki Nishi, Hiroshi Takeshima
TRIC-A and TRIC-B proteins form homotrimeric cation-permeable channels in the sarco/endoplasmic reticulum (SR/ER) and nuclear membranes and are thought to contribute to counterionic flux coupled with store Ca2+release in various cell types. Serious m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3327ad08c0aca741032b91dd88285d6c
https://doi.org/10.1101/2023.02.28.530410
https://doi.org/10.1101/2023.02.28.530410
Autor:
Shinji Komazaki, Naoto Ninomiya, Mari Sekine, Taka-aki K. Noguchi, Pi-Chao Wang, Akira Kurisaki, Makoto Asashima
Publikováno v:
Nature Cell Biology. 17:984-993
Successful pluripotent stem cell differentiation methods have been developed for several endoderm-derived cells, including hepatocytes, β-cells and intestinal cells. However, stomach lineage commitment from pluripotent stem cells has remained a chal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85364b28bea211ae719e11fd1728d0ee
https://doi.org/10.1038/ncb3200
https://doi.org/10.1038/ncb3200
Autor:
Junken Aoki, Tomomi Ueyama, Keita Nakanaga, Bo Van, Ki Ho Park, Atsuhiko Ichimura, Jianjie Ma, Hiroshi Takeshima, Takehiro Ogata, Naoki Maruyama, Miyuki Nishi, Shinji Komazaki, Sho Kakizawa
Publikováno v:
FEBS Letters. 589:1095-1104
Mitsugumin 56 (MG56), also known as the membrane-bound O-acyl-transferase family member hedgehog acyltransferase-like, was identified as a new sarcoplasmic reticulum component in striated muscle. Mg56-knockout mice grew normally for a week after birt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04551ccb2d7f771b654c8d5317ac7c5
https://doi.org/10.1016/j.febslet.2015.03.028
https://doi.org/10.1016/j.febslet.2015.03.028
Autor:
Jianjie Ma, Ki Ho Park, Michael X. Zhu, Pei-Hui Lin, Antony Galione, A. Mark Evans, John Parrington, Pu Duann, Mingzhai Sun, Matthew Sermersheim, Kristyn Gumpper, Haichang Li, Shinji Komazaki
Publikováno v:
The Journal of Biological Chemistry
Background: The endolysosomal TPC2 ion channel interacts with mTOR to regulate cellular energy utilization. Results: Mice lacking TPC2 display muscle atrophy phenotype with reduced muscle endurance, altered autophagy, and lysosomal enzymatic activiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08f7f3f9feb5375e7d70107ef2d3c2e
http://europepmc.org/articles/PMC4319008
http://europepmc.org/articles/PMC4319008
Autor:
Seon-Hye E. Park, Fan Shi, Masayuki Yazawa, Shinji Komazaki, Fuun Kawano, Yusuke Hirabayashi, Franck Polleux
Publikováno v:
ACS synthetic biology. 7(1)
The organelle interface emerges as a dynamic platform for a variety of biological responses. However, their study has been limited by the lack of tools to manipulate their occurrence in live cells spatiotemporally. Here, we report the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda6067287b93999022fc13140011c67
https://pubmed.ncbi.nlm.nih.gov/29172503
https://pubmed.ncbi.nlm.nih.gov/29172503
Autor:
Nobuyuki Takakura, Takeshi Yamashita, Shinichiro Yamamoto, Masaya Matsubayashi, Sho Kakizawa, Shinji Komazaki, Hiroyasu Kidoya, Masako Osaki, Tetsuo Yamazaki, Daiju Yamazaki
Publikováno v:
Developmental Biology. 393(1):33-43
Calumin is an endoplasmic reticulum (ER)-transmembrane protein, and little is known about its physiological roles. Here we showed that calumin homozygous mutant embryos die at embryonic days (E) 10.5−11.5. At mid-gestation, calumin was expressed pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1284699eff3e80f4799292ae308e70eb