Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Shinji Kizuki"'
Publikováno v:
Journal of Pharmaceutical Sciences. 112:492-505
An increase in protein aggregates during transportation should be suppressed in therapeutic protein products because the aggregates have a potential risk of immunogenicity. In this study, three protein solutions in vials were exposed to tri-axial vib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457a755fa15fd10ceeab73edb088db6d
https://doi.org/10.1016/j.xphs.2022.09.022
https://doi.org/10.1016/j.xphs.2022.09.022
Autor:
Tomohiro Asai, Hiroshi Kiwada, Tatsuaki Tagami, Jose Mario Barichello, Naoto Oku, Hiroshi Kikuchi, Tatsuhiro Ishida, Shinji Kizuki
Publikováno v:
International Journal of Pharmaceutics. 410:153-160
The successful delivery of therapeutic siRNA to the designated target cells and their availability at the intracellular site of action are crucial requirements for successful RNAi therapy. In the present study, we focused on the siRNA-lipoplex prepar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1aa3590530ea36438f57d4aecfe6835
https://doi.org/10.1016/j.ijpharm.2011.03.001
https://doi.org/10.1016/j.ijpharm.2011.03.001
Publikováno v:
Journal of Controlled Release. 137:8-14
We recently designed a PEG-coated cationic liposome targeted to angiogenic vessels and showed, in a murine dorsal air sac model, potent anti-angiogenic activity of an oxaliplatin (l-OHP) formulation of this liposome. In the present study, we extended
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df015870851a18279f72f531c2bf796
https://doi.org/10.1016/j.jconrel.2009.02.023
https://doi.org/10.1016/j.jconrel.2009.02.023
Autor:
Shinji Kizuki, Jose Mario Barichello, Hiroshi Kiwada, Tatsuhiro Ishida, Hiroshi Kikuchi, Luiz Alberto Lira Soares, Tatsuaki Tagami
Publikováno v:
International journal of pharmaceutics. 430(1-2)
We recently demonstrated that agitation during lipoplex formation (vorLTsiR) improves the gene knockdown effect of siRNA because the resultant decrease in lipoplex size leads to an enhanced uptake by cells. In furthering this line of research, the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d582b4db6303b5337e00a72e91695398
https://pubmed.ncbi.nlm.nih.gov/22525078
https://pubmed.ncbi.nlm.nih.gov/22525078