Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Shinji Kamimura"'
Autor:
Andrea E Prota, Daniel Lucena-Agell, Yuntao Ma, Juan Estevez-Gallego, Shuo Li, Katja Bargsten, Fernando Josa-Prado, Karl-Heinz Altmann, Natacha Gaillard, Shinji Kamimura, Tobias Mühlethaler, Federico Gago, Maria A Oliva, Michel O Steinmetz, Wei-Shuo Fang, J Fernando Díaz
Publikováno v:
eLife, Vol 12 (2023)
Paclitaxel (Taxol) is a taxane and a chemotherapeutic drug that stabilizes microtubules. While the interaction of paclitaxel with microtubules is well described, the lack of high-resolution structural information on a tubulin-taxane complex precludes
Externí odkaz:
https://doaj.org/article/ae0411d1a2f8477a839b678a56356407
Autor:
Juan Estévez-Gallego, Fernando Josa-Prado, Siou Ku, Ruben M Buey, Francisco A Balaguer, Andrea E Prota, Daniel Lucena-Agell, Christina Kamma-Lorger, Toshiki Yagi, Hiroyuki Iwamoto, Laurence Duchesne, Isabel Barasoain, Michel O Steinmetz, Denis Chrétien, Shinji Kamimura, J Fernando Díaz, Maria A Oliva
Publikováno v:
eLife, Vol 9 (2020)
Microtubules (MTs) are hollow cylinders made of tubulin, a GTPase responsible for essential functions during cell growth and division, and thus, key target for anti-tumor drugs. In MTs, GTP hydrolysis triggers structural changes in the lattice, which
Externí odkaz:
https://doaj.org/article/eb49d1e2fe6445b783e2a3c85b0c7bbb
Autor:
Daisuke Miyashiro, Kogiku Shiba, Tahahiro Miyashita, Shoji A. Baba, Manabu Yoshida, Shinji Kamimura
Publikováno v:
Biology Open, Vol 4, Iss 2, Pp 109-118 (2015)
During their chemotactic swimming toward eggs, sperm cells detect their species-specific chemoattractant and sense concentration gradients by unknown mechanisms. After sensing the attractant, sperm cells commonly demonstrate a series of responses inv
Externí odkaz:
https://doaj.org/article/6251e379367d4e039e866efaee06bb50
Publikováno v:
ACS Omega. 8:3540-3550
11 p.-3 fig.
Microtubules (MTs) are essential cellular machines built from concatenated αβ-tubulin heterodimers. They are responsible for two central and opposite functions from the dynamic point of view: scaffolding (static filaments) and for
Microtubules (MTs) are essential cellular machines built from concatenated αβ-tubulin heterodimers. They are responsible for two central and opposite functions from the dynamic point of view: scaffolding (static filaments) and for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba1f4d0949e4943d2b2c28dae876d85
https://doi.org/10.1021/acsomega.2c06926
https://doi.org/10.1021/acsomega.2c06926
Autor:
Toshio Inoda, Shinji Kamimura
Publikováno v:
Aquatic Insects. :1-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65cc612066274b90b8e25af0cb587df4
https://doi.org/10.1080/01650424.2022.2076883
https://doi.org/10.1080/01650424.2022.2076883
Autor:
Andrea E Prota, Daniel Lucena-Agell, Yuntao Ma, Juan Estevez-Gallego, Shuo Li, Katja Bargsten, Fernando Josa-Prado, Karl-Heinz Altmann, Natacha Gaillard, Shinji Kamimura, Tobias Mühlethaler, Federico Gago, Maria A Oliva, Michel O Steinmetz, Wei-Shuo Fang, J Fernando Díaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6031650b263dc281c6bcce2894cf2134
https://doi.org/10.7554/elife.84791.sa2
https://doi.org/10.7554/elife.84791.sa2
Autor:
Juan Estévez-Gallego, Beatriz Álvarez-Bernad, Benet Pera, Christoph Wullschleger, Olivier Raes, Dirk Menche, Juan Carlos Martínez, Daniel Lucena-Agell, Andrea E. Prota, Francesca Bonato, Katja Bargsten, Jelle Cornelus, Juan Francisco Giménez-Abián, Peter Northcote, Michel O. Steinmetz, Shinji Kamimura, Karl-Heinz Altmann, Ian Paterson, Federico Gago, Johan Van der Eycken, J. Fernando Díaz, María Ángela Oliva
Publikováno v:
Structure, 31 (1)
17 p.-5 fig.1 graph. abst.
Taxanes are microtubule-stabilizing agents used in the treatment of many solid tumors, but they often involve side effects affecting the peripheral nervous system. It has been proposed that this could be related to str
Taxanes are microtubule-stabilizing agents used in the treatment of many solid tumors, but they often involve side effects affecting the peripheral nervous system. It has been proposed that this could be related to str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee53e9443e0472be4953641abf09b89
Autor:
Prota, Andrea E., Lucena-Agell, Daniel, Yuntao Ma, Estevez-Gallego, Juan, Shuo Li, Bargsten, Katja, Josa-Prado, Fernando, Altmann, Karl-Heinz, Gaillard, Natacha, Shinji Kamimura, Mühlethaler, Tobias, Gago, Federico, Oliva, Maria A., Steinmetz, Michel O., Wei-Shuo Fang, Díaz, J. Fernando
Publikováno v:
eLife; 3/28/2023, p1-35, 35p
Autor:
Wei-Shuo Fang, Shinji Kamimura, Juan F. Giménez-Abián, María A. Oliva, Yun-Tao Ma, Juan Estévez-Gallego, J. Fernando Díaz, Andrea E. Prota, Daniel Lucena-Agell, Katja Bargsten, Kenneth Goossens, Shuo Li, José Manuel Andreu, Natacha Olieric, Carlos Roca, Michel O. Steinmetz, Tobias Mühlethaler, Ángeles Canales, Fernando Josa-Prado, Karl-Heinz Altmann
Paclitaxel (Taxol®) is a taxane and a first-line chemotherapeutic drug that stabilizes microtubules. While the interaction of paclitaxel with microtubules is well described, the current lack of high-resolution structural information on a tubulin-tax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bc20ec6d6b1ba8992558ceb43d8dba4
https://doi.org/10.1101/2021.07.20.453061
https://doi.org/10.1101/2021.07.20.453061
Autor:
Shinji Kamimura, Rie Ayukawa, Seigo Iwata, Benoît Gigant, Kien Xuan Ngo, Hiroshi Imai, Masahito Hayashi, Mikako Shirouzu, Itsushi Minoura, Ken Sekimoto, Etsuko Muto, Hideki Shigematsu, Tsukasa Makino, Seiichi Uchimura
Publikováno v:
Journal of Cell Biology
Journal of Cell Biology, 2021, 220 (e202007033), ⟨10.1083/jcb.202007033⟩
Journal of Cell Biology, 2021, 220, ⟨10.1083/jcb.202007033⟩
Journal of Cell Biology, Rockefeller University Press, 2021, 220, ⟨10.1083/jcb.202007033⟩
The Journal of Cell Biology
'Journal of Cell Biology ', vol: 220, pages: e202007033-1-e202007033-19 (2021)
Journal of Cell Biology, 2021, 220 (e202007033), ⟨10.1083/jcb.202007033⟩
Journal of Cell Biology, 2021, 220, ⟨10.1083/jcb.202007033⟩
Journal of Cell Biology, Rockefeller University Press, 2021, 220, ⟨10.1083/jcb.202007033⟩
The Journal of Cell Biology
'Journal of Cell Biology ', vol: 220, pages: e202007033-1-e202007033-19 (2021)
Ayukawa, Iwata, Imai, et al. visualize the early intermediates in the pathway of spontaneous nucleation of microtubules by using rapid flush negative stain electron microscopy. This study demonstrates that the formation of straight tubulin oligomers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb7d0964587e9adf6460d548336fe3e
https://hal.science/hal-03141626
https://hal.science/hal-03141626