Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Shinji Kajimoto"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Liquid–liquid phase separation is a phenomenon that features the formation of liquid droplets containing concentrated solutes. The droplets of neurodegeneration-associated proteins are prone to generate aggregates and cause diseases. To un
Externí odkaz:
https://doaj.org/article/70a275a5ba0d4764b41419c39bc9911b
Autor:
Hironobu Fukuzawa, Tsukasa Takanashi, Edwin Kukk, Koji Motomura, Shin-ichi Wada, Kiyonobu Nagaya, Yuta Ito, Toshiyuki Nishiyama, Christophe Nicolas, Yoshiaki Kumagai, Denys Iablonskyi, Subhendu Mondal, Tetsuya Tachibana, Daehyun You, Syuhei Yamada, Yuta Sakakibara, Kazuki Asa, Yuhiro Sato, Tsukasa Sakai, Kenji Matsunami, Takayuki Umemoto, Kango Kariyazono, Shinji Kajimoto, Hikaru Sotome, Per Johnsson, Markus S. Schöffler, Gregor Kastirke, Kuno Kooser, Xiao-Jing Liu, Theodor Asavei, Liviu Neagu, Serguei Molodtsov, Kohei Ochiai, Manabu Kanno, Kaoru Yamazaki, Shigeki Owada, Kanade Ogawa, Tetsuo Katayama, Tadashi Togashi, Kensuke Tono, Makina Yabashi, Aryya Ghosh, Kirill Gokhberg, Lorenz S. Cederbaum, Alexander I. Kuleff, Hiroshi Fukumura, Naoki Kishimoto, Artem Rudenko, Catalin Miron, Hirohiko Kono, Kiyoshi Ueda
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Understanding strong X-ray induced phenomena is important for applications of X-ray free-electron laser imaging. Here, the authors show time-resolved measurements of X-ray free-electron laser induced electronic decay of CH2I2 molecule probed with NIR
Externí odkaz:
https://doaj.org/article/92903fed943349d7a69ef7b3b9aa3fab
Autor:
Masato Machida, Toshiki Sugimura, Shinji Kajimoto, Farsai Taemaitree, Yoshitaka Koseki, Hitoshi Kasai, Takakazu Nakabayashi
Publikováno v:
The Journal of Physical Chemistry B. 127:3851-3860
Autor:
Hiroyuki Yamakoshi, Daiki Shibata, Kazuki Bando, Shinji Kajimoto, Aki Kohyama, Syusuke Egoshi, Kosuke Dodo, Yoshiharu Iwabuchi, Mikiko Sodeoka, Katsumasa Fujita, Takakazu Nakabayashi
Most Raman sensors are based on Raman tags linked to bulky aromatic molecules that affect the subcellular localization. Therefore, here, we developed a small ratiometric Raman sensor, ThioRas, to effectively detect thiols in live cells. ThioRas has a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d1af2f04e6cb00f5ae63de7c8abcfac
https://doi.org/10.26434/chemrxiv-2023-0lkm0
https://doi.org/10.26434/chemrxiv-2023-0lkm0
Autor:
Ren Shibuya, Shinji Kajimoto, Hideyuki Yaginuma, Tetsuro Ariyoshi, Yasushi Okada, Takakazu Nakabayashi
Liquid droplets formed via intracellular Liquid–liquid phase separation (LLPS) are called membraneless organelles and provide enzymatic reaction fields for maintaining cellular homeostasis, while they can be sources of protein aggregates and fibril
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67ecdfa664ca629d8fc5b0b010431434
https://doi.org/10.1101/2023.05.15.540722
https://doi.org/10.1101/2023.05.15.540722
Autor:
Kohei Yokosawa, Shinji Kajimoto, Daiki Shibata, Kunisato Kuroi, Tomohiro Konno, Takakazu Nakabayashi
Publikováno v:
The Journal of Physical Chemistry Letters. 13:5692-5697
Liquid-liquid phase separation (LLPS) is an important phenomenon in biology, and it is desirable to develop quantitative methods to analyze protein droplets generated by LLPS. This study quantified the change in protein concentration in a droplet in
Autor:
Shinji Kajimoto, Takakazu Nakabayashi, Daiki Shibata, Kunisato Kuroi, Kazuki Murakami, Fumihiko Fujii
Publikováno v:
Chemical Science
Liquid–liquid phase separation (LLPS) plays an important role in a variety of biological processes and is also associated with protein aggregation in neurodegenerative diseases. Quantification of LLPS is necessary to elucidate the mechanism of LLPS
Publikováno v:
Physical Chemistry Chemical Physics. 22:21646-21650
We report the dynamics of lipid droplet formation induced by introducing cis- and/or trans-fatty acids into cells. Raman imaging allows the chemical analysis of each droplet, showing that exogenous fatty acids initially enter original endogenous drop
Publikováno v:
The journal of physical chemistry. B. 125(38)
Stimulation of cells by nanosecond pulsed electric fields (nsPEFs) has attracted attention as a technology for medical applications such as cancer treatment. nsPEFs have been shown to affect intracellular environments without significant damage to ce
Autor:
Shuichi Toyouchi, Masatoshi Toda, Toshihiro Kawakatsu, Yohji Akama, Motoko Kotani, Hiroshi Fukumura, Shinji Kajimoto
Publikováno v:
The Journal of Physical Chemistry B. 122:12375-12385
Phase separation dynamics of a water/2-butoxyethanol (2BE) mixture was studied with newly developed time-resolved structured illumination microscopy (SIM). Interestingly, an employed hydrophobic fluorescent probe for SIM showed spectral shifts up to