Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Shinji Kaichi"'
Autor:
Atsushi Yokota, Takahisa Horita, Hideaki Koga, Takumi Fukuchi, Akira Ishikawa, Ryota Araki, Keiji Shimazu, Shinji Kaichi, Masahiro Kyo, Takaaki Eguchi, Yukiomi Namba
Publikováno v:
Therapeutic Apheresis and Dialysis. 23:224-232
Twice-weekly intensive granulocyte/monocyte adsorptive apheresis is effective and safe for ulcerative colitis, but maintaining two blood access routes is problematic. We previously reported that intensive granulocyte/monocyte adsorptive apheresis usi
Publikováno v:
Pediatric Cardiology and Cardiac Surgery. 32:534-539
Publikováno v:
Pediatric Cardiology. 32:94-97
Drug-eluting stents (DES) have markedly reduced the incidence of coronary in-stent restenosis. However, DES may be still vulnerable to coronary thrombus, and the long-term outcome remains unknown, especially in infancy. Here, we present a 9-month-old
Autor:
Toshio Heike, Akira Shimatsu, Koh Ono, Tomohide Takaya, Tatsuya Morimoto, Shiro Baba, Tatsutoshi Nakahata, Koji Hasegawa, Yoichi Sunagawa, Teruhisa Kawamura, Shinji Kaichi
Publikováno v:
Journal of Cellular Physiology. 226:248-254
The treatment of ES cells with trichostatin A (TSA), an HDAC inhibitor, induces the acetylation of GATA4 as well as histones, andfacilitatestheirdifferentiationintocardiomyocytes.Recently,wedemonstratedthatcyclin-dependentkinase9(Cdk9),acorecomponent
Autor:
Toru Kita, Hiromichi Wada, Tomohide Takaya, Shinji Kaichi, Tatsuya Morimoto, Yoichi Sunagawa, Masatoshi Fujita, Teruhisa Kawamura, Koji Hasegawa, Akira Shimatsu
Publikováno v:
Journal of Biological Chemistry. 285:9556-9568
A zinc finger protein GATA4 is one of the hypertrophy-responsive transcription factors and forms a complex with an intrinsic histone acetyltransferase, p300. Disruption of this complex results in the inhibition of cardiomyocyte hypertrophy and heart
Autor:
Shinya Yamanaka, Shinji Kaichi, Tatsutoshi Nakahata, Takahiro Mima, Shiro Baba, Noritaka Yokoo, Akira Niwa, Toshio Heike, Hiraku Doi
Publikováno v:
Biochemical and Biophysical Research Communications. 387(3):482-488
Developing effective drug therapies for arrhythmic diseases is hampered by the fact that the same drug can work well in some individuals but not in others. Human induced pluripotent stem (iPS) cells have been vetted as useful tools for drug screening
Autor:
Hiraku Doi, Toshio Heike, Mito Kanatsu-Shinohara, Shiro Baba, Tatsutoshi Nakahata, Toru Iwasa, Takashi Shinohara, Noritaka Yokoo, Shinji Kaichi, Takahiro Mima
Publikováno v:
Biochemical and biophysical research communications. 400(1)
Multipotent germline stem (mGS) cells have been established from neonatal mouse testes. We previously reported that undifferentiated mGS cells are phenotypically similar to embryonic stem cells and that fetal liver kinase 1 (Flk1)(+) mGS cells have a
Autor:
Takahiro Mima, Shinji Kaichi, Tatsuya Morimoto, Tatsutoshi Nakahata, Toshio Heike, Shiro Baba, Tomohide Takaya, Hiraku Doi, Teruhisa Kawamura, Shinya Yamanaka, Koh Ono, Koji Hasegawa, Noritaka Yokoo
Publikováno v:
Cardiovascular research. 88(2)
Aims Mouse and human fibroblasts can be directly reprogrammed to pluripotency by the ectopic expression of four transcription factors (Oct3/4, Sox2, Klf4, and c-Myc) to yield induced pluripotent stem (iPS) cells. iPS cells can be generated even witho
Autor:
Takahiro Doi, Takahiro Mima, Noritaka Yokoo, Shinji Kaichi, Hiraku Doi, Toshio Heike, Shiro Baba
Publikováno v:
Journal of Cardiothoracic Surgery
Journal of Cardiothoracic Surgery, Vol 5, Iss 1, p 47 (2010)
Journal of Cardiothoracic Surgery, Vol 5, Iss 1, p 47 (2010)
Cardiac resynchronization therapy (CRT) is a new treatment for refractory heart failure. However, most heart failure patients treated with CRT are middle-aged or old patients with idiopathic or ischemic dilated cardiomyopathy. We treated a 17 year 11
Autor:
Koji Hasegawa, Koh Ono, Tatsuya Morimoto, Shinji Kaichi, Toru Kita, Tomohide Takaya, Hiromichi Wada, Teruhisa Kawamura, Rieko Takanabe, Akira Shimatsu
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 73(8)
Background: MicroRNAs (miRNAs) regulate various biological processes through inhibiting the translation of RNA transcripts. Although miRNA-1 (miR-1) and miRNA-133 (miR-133) are abundantly expressed in the adult heart and involved in cardiac hypertrop