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pro vyhledávání: '"Shinji HISADA"'
Autor:
Shinji Hisada, Etsuhisa Kuwahara, Norimitsu Takahashi, Takayoshi Shimizu, Makoto Tanaka, Hirotaka Chikazawa
Publikováno v:
Biological and Pharmaceutical Bulletin. 22:521-526
The rectal absorption of a platinum anti-tumor agent, [bis (acetato) ammine dichloro (cyclohexylamine) platinum(IV)] (BMS-182751), was investigated in rats. BMS-182751 was co-ground with various carriers to improve its poor aqueous solubility. The hi
Autor:
Toshihito KADOTA, Hiroshi KONDOH, Hirotaka CHIKAZAWA, Kohji KUROYANAGI, Norimiti HATTORI, Katsumi ISHIKAWA, Shigeo KAWANO, Kayo SAKAKURA, Shigeru KOIZUMI, Eiko HIRAIWA, Shinji HISADA, Shuichi KAI, Hisashi KOHMURA, Norimitsu TAKAHASHI
Publikováno v:
The Journal of Toxicological Sciences. 19:35-55
Paclitaxel, an antineoplastic agent, was intravenously given to Crj:CD (SD) rats of both sexes at 0 (saline), 0 (vehicle), 1.0 (low dose), 3.3 (intermediate dose) and 10.0 (high dose) mg/kg at five-day interval over one-month period (6 times in total