The novel carboxamide analog ITR-284 induces caspase-dependent apoptotic cell death in human hepatocellular and colorectal cancer cells

Autor: Shinji Fushiya, Yen Fang Wen, Sheng-Chu Kuo, Kuang Chi Lai, Tian Shung Wu, Chi Cheng Lu, Yu Ren Liao, Jai Sing Yang

Publikováno v: Molecular Medicine Reports. 7:1539-1544

We have previously reported that ITR-284, a potent carboxamide-derived anticancer agent, induced apoptosis in leukemia cells. However, there are no reports showing that ITR-284 inhibits human hepatocellular and colorectal cancer cells. In this study,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adeb7775e7e352947b9e8d7c3eed1a76
https://doi.org/10.3892/mmr.2013.1359

Oral administration of Ren-shen-yang-rong-tang 'ninjin'yoeito' protects against hematotoxicity and induces immature erythroid progenitor cells in 5-Fluorouracil-induced anemia

Autor: Yasuyuki Ohta, Tomoya Takahashi, Tomihisa Ohta, Nobuo Yahagi, Kenroh Sasaki, Shinji Fushiya, Kyoko Kobayashi, Fumihiko Yoshizaki, Tomoaki Tanaka, Fumihide Takano

Publikováno v: Evidence-Based Complementary and Alternative Medicine, Vol 6, Iss 2, Pp 247-256 (2009)
Evidence-based Complementary and Alternative Medicine : eCAM

金沢大学医薬保健研究域薬学系
The purpose of this study was to investigate the efficacy of four different Japanese and Chinese herbal prescriptions, Ren-Shen-Yang-Rong-Tang (Ninjin'yoeito, NYT), Chai-Hu-Gui-Zhi-Gan-Jiang-Tang (Saiko

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd9a29d1beec22ac0867e459af4fdbe
http://hdl.handle.net/2297/19631

Constituents ofRhodiola roseaShowing Inhibitory Effect on Lipase Activity in Mouse Plasma and Alimentary Canal

Autor: Kyoko Kobayashi, Shinji Fushiya, Fumihide Takano, Keiko Yamada, Toshihiro Murata, Javzan Batkhuu, Tatsuya Hasegawa, Kazutaka Koga, Fumihiko Yoshizaki

Publikováno v: Planta Medica. 74:1716-1719

As a methanol extract of the rhizome of Rhodiola rosea inhibits the activity of lipase in isolated mouse plasma in vitro and in the mouse gastrointestinal tube in vivo, the active components in this plant were investigated. After fractionation and se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fd46513374b139b62bea4acafcae63
https://doi.org/10.1055/s-0028-1088318

Distinction of water-soluble constituents between some Paecilomyces (= Isaria) and Cordyceps fungi by capillary electrophoresis

Autor: Shinji Fushiya, Fumihiko Yoshizaki, Kyoko Kobayashi, Tomoko Ogiwara, Fumihide Takano, Remiko Yahagi, Tomihisa Ohta, Nobuo Yahagi, Satomi Ihara

Publikováno v: Journal of Natural Medicines. 60:243-247

In order to reveal the differences between Cordyceps, Paecilomyces (= Isaria) and Nomuraea, we collected seven entomogenous fungi grown in natural field and analyzed the profiles of water-soluble constituents derived from some different sources of Co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4123cfdcb25883a0c3dd18a2488fa8
https://doi.org/10.1007/s11418-006-0034-6

Water-soluble extracts from Angelica acutiloba Kitagawa enhance hematopoiesis by activating immature erythroid cells in mice with 5-fluorouracil-induced anemia

Autor: Tomoaki Tanaka, Fumihide Takano, Mitsunobu Matsubara, Michiko Suzuki, Itsuro Kazama, Mari Michimata, Shinji Fushiya, Ryo Hatano

Publikováno v: Experimental Hematology. 32:918-924

The extract from the root of Angelica acutiloba Kitagawa ( AR ), which is used as herbal medicine in Japan, has been reported to be clinically effective for postmenstrual blood loss and erythropoietin (EPO)-resistant anemia in chronic renal failure,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4408f0d12d8930858778ef59bb64d8
https://doi.org/10.1016/j.exphem.2004.07.003