Zobrazeno 1 - 10
of 289
pro vyhledávání: '"Shinji Deguchi"'
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 8, p e1012312 (2024)
Cells exhibit various morphological characteristics due to their physiological activities, and changes in cell morphology are inherently accompanied by the assembly and disassembly of the actin cytoskeleton. Stress fibers are a prominent component of
Externí odkaz:
https://doaj.org/article/1b5d1fd1b598470a93255019a0c1fff5
Publikováno v:
APL Machine Learning, Vol 1, Iss 4, Pp 046111-046111-7 (2023)
Recently, the incorporation of machine learning (ML) has heralded significant advancements in materials science. For instance, in spintronics, it has been shown that magnetic parameters, such as the Dzyaloshinskii–Moriya interaction, can be estimat
Externí odkaz:
https://doaj.org/article/a3113ba30eff4ebd872457b90d510f82
Publikováno v:
Journal of Biomechanical Science and Engineering, Vol 18, Iss 4, Pp 23preface1-23preface1 (2023)
Externí odkaz:
https://doaj.org/article/ea434deea774481982d625a52ab7db99
Autor:
Hiroki Hamaguchi, Tsubasa S. Matsui, Shinji Deguchi, Yasuro Furuichi, Nobuharu L. Fujii, Yasuko Manabe
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Muscle weakness is detrimental not only to quality of life but also life expectancy. However, effective drugs have still not been developed to improve and prevent muscle weakness associated with aging or diseases. One reason for the delay in
Externí odkaz:
https://doaj.org/article/0481dc4b771f470894590f4e96fc4454
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Tensional homeostasis is a cellular process whereby nonmuscle cells such as fibroblasts keep a constant level of intracellular tension and signaling activities. Cells are allowed thanks to tensional homeostasis to adapt to mechanical stress,
Externí odkaz:
https://doaj.org/article/32c043d58c1e495885bee5ec33c121e7
Autor:
Takumi SAITO, Shinji DEGUCHI
Publikováno v:
Journal of Biomechanical Science and Engineering, Vol 18, Iss 4, Pp 23-00028-23-00028 (2023)
Intracellular proteins are continuously replaced over time by chemical reaction called molecular turnover. Fluorescence recovery after photobleaching (FRAP) is a powerful technique to evaluate the turnover in living cells. In short-term FRAP measurem
Externí odkaz:
https://doaj.org/article/7e53ef73057c466cbdce7bfd14a31011
Autor:
Honghan Li, Daiki Matsunaga, Tsubasa S. Matsui, Hiroki Aosaki, Genki Kinoshita, Koki Inoue, Amin Doostmohammadi, Shinji Deguchi
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
A deep learning approach, termed wrinkle force microscopy, allows for conducting traction force microscopy by observing bright-field cell images but without using its conventional requirements such as fluorescent microbeads and confocal microscopy.
Externí odkaz:
https://doaj.org/article/c76434e78fae445c90be394666290aed
Autor:
Nanami Ueda, Masashi Maekawa, Tsubasa S. Matsui, Shinji Deguchi, Tomoyo Takata, Jun Katahira, Shigeki Higashiyama, Miki Hieda
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The linker of nucleoskeleton and cytoskeleton (LINC) complex is composed of the inner nuclear membrane-spanning SUN proteins and the outer nuclear membrane-spanning nesprin proteins. The LINC complex physically connects the nucleus and plasma membran
Externí odkaz:
https://doaj.org/article/15fb16ce55f94ddb8c46950153f26deb
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0276909 (2022)
Fluorescence recovery after photobleaching (FRAP) is a versatile technique to evaluate the intracellular molecular exchange called turnover. Mechanochemical models of FRAP typically consider the molecular diffusion and chemical reaction that simultan
Externí odkaz:
https://doaj.org/article/0d26823b33374e2e84dcd9659ae1c012
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195124 (2018)
Cell-substrate adhesions are essential for various physiological processes, including embryonic development and maintenance of organ functions. Hemidesmosomes (HDs) are multiprotein complexes that attach epithelial cells to the basement membrane. For
Externí odkaz:
https://doaj.org/article/9b1d211179304c74a50bcdeb9e841d5b