Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Shinji Asano"'
Autor:
Shota Okamoto, Makoto Yasuda, Kotoku Kawaguchi, Kasane Yasuoka, Yumi Kikukawa, Shinji Asano, Taisei Tsujii, Sana Inoue, Kikuko Amagase, Taka-aki Inui, Shigeru Hirano, Toshio Inui, Yoshinori Marunaka, Takashi Nakahari
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 9069 (2024)
An application of CO2/HCO3−-free solution (Zero-CO2) did not increase intracellular pH (pHi) in ciliated human nasal epithelial cells (c-hNECs), leading to no increase in frequency (CBF) or amplitude (CBA) of the ciliary beating. This study demonst
Externí odkaz:
https://doaj.org/article/9300c44f711544318710514fbd37be99
Autor:
Seiichi Morokuma, Toshinari Hayashi, Masatomo Kanegae, Yoshihiko Mizukami, Shinji Asano, Ichiro Kimura, Yuji Tateizumi, Hitoshi Ueno, Subaru Ikeda, Kyuichi Niizeki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Deep learning methods have gained significant attention in sleep science. This study aimed to assess the performance of a deep learning-based sleep stage classification model constructed using fewer physiological parameters derived from card
Externí odkaz:
https://doaj.org/article/1f5a643f6e8045aca78741d4d50bb7f4
Autor:
Akari Kobayashi, Kotoku Kawaguchi, Shinji Asano, Hong Wu, Takashi Nakano, Toshio Inui, Yoshinori Marunaka, Takashi Nakahari
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8138 (2024)
Single cilia, 100 nm in diameter and 10 µm in length, were isolated from mouse tracheae with Triton X-100 (0.02%) treatment, and the effects of pH on ciliary beating were examined by measuring the ciliary beat frequency (CBF) and the ciliary bend di
Externí odkaz:
https://doaj.org/article/f7fd1ba359c7434eb50031cd6e4c0d59
Autor:
Takashi Nakahari, Chihiro Suzuki, Kotoku Kawaguchi, Shigekuni Hosogi, Saori Tanaka, Shinji Asano, Toshio Inui, Yoshinori Marunaka
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16976 (2023)
Ambroxol (ABX), a frequently prescribed secretolytic agent which enhances the ciliary beat frequency (CBF) and ciliary bend angle (CBA, an index of amplitude) by 30%, activates a voltage-dependent Ca2+ channel (CaV1.2) and a small transient Ca2+ rele
Externí odkaz:
https://doaj.org/article/aab5079ded5047309d8f4b083ef4aeb1
Autor:
Yukiko Ikeuchi-Yamamoto, Haruka Kogiso, Daichi Saito, Kotoku Kawaguchi, Riko Ikeda, Shinji Asano, Toshio Inui, Yoshinori Marunaka, Takashi Nakahari
Publikováno v:
Phytomedicine Plus, Vol 2, Iss 2, Pp 100243- (2022)
Background: Hochu-ekki-to (TJ-41, a traditional herbal medicine) is used for preventing airway infections caused by viruss or bacterias in patients with chronic obstructive pulmonary disease (COPD). TJ-41 is known to inhibit viral adhesion and to act
Externí odkaz:
https://doaj.org/article/867328f2ab0e48e89d6fe03c2913b2a6
Autor:
Kotoku Kawaguchi, Shinji Asano
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3246 (2022)
Ezrin is one of the members of the ezrin/radixin/moesin (ERM) family of proteins. It was originally discovered as an actin-binding protein in the microvilli structure about forty years ago. Since then, it has been revealed as a key protein with funct
Externí odkaz:
https://doaj.org/article/eaedd3f99def4e70ad849acba002f73e
Autor:
Makoto Yasuda, Taka-aki Inui, Shigeru Hirano, Shinji Asano, Tomonori Okazaki, Toshio Inui, Yoshinori Marunaka, Takashi Nakahari
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 4052 (2020)
Small inhaled particles, which are entrapped by the mucous layer that is maintained by mucous secretion via mucin exocytosis and fluid secretion, are removed from the nasal cavity by beating cilia. The functional activities of beating cilia are asses
Externí odkaz:
https://doaj.org/article/6e1ec38c402b44d186c7a57dbab52327
Autor:
Haruka Kogiso, Matthieu Raveau, Kazuhiro Yamakawa, Daichi Saito, Yukiko Ikeuchi, Tomonori Okazaki, Shinji Asano, Toshio Inui, Yoshinori Marunaka, Takashi Nakahari
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 1947 (2020)
In Ts1Rhr, a Down syndrome model mouse, the airway ciliary beatings are impaired; that is, decreases in ciliary beat frequency (CBF) and ciliary bend angle (CBA, an index of ciliary beat amplitude)). A resumption to two copies of the Pcp4 gene on the
Externí odkaz:
https://doaj.org/article/7d67c973b98a4da1858611a239f0d362
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105435 (2014)
Neuronal morphogenesis is implicated in neuronal function and development with rearrangement of cytoskeletal organization. Ezrin, a member of Ezrin/Radixin/Moesin (ERM) proteins links between membrane proteins and actin cytoskeleton, and contributes
Externí odkaz:
https://doaj.org/article/25bdfd29a64d48e2aeae581de9a9bf65
Autor:
Kohei, Takahashi, Yuko, Kuwahara, Ikuo, Kato, Shinji, Asano, Takaharu, Kozakai, Yoshinori, Marunaka, Atsukazu, Kuwahara
Publikováno v:
Biomedical Research. 43:223-239
The inhibitory action of the secondary bile acid lithocholic acid (LCA) on neurally evoked Cl