Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Shinji Aki"'
Autor:
Sayaka Nagasawa, Yuichiro Hirata, Sho Miyamoto, Seiya Ozono, Shun Iida, Harutaka Katano, Shigeki Tsuneya, Kei Kira, Susumu Kobayashi, Makoto Nakajima, Hiroyuki Abe, Masako Ikemura, Isao Yamamoto, Kimiko Nakagawa, Kazumi Kubota, Shinji Akitomi, Iwao Hasegawa, Tetsuo Ushiku, Tadaki Suzuki, Hirotaro Iwase, Yohsuke Makino, Hisako Saitoh
Publikováno v:
PLoS ONE, Vol 19, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/4f93664655c94bb5a0659996bb47edc7
Autor:
Hisako Saitoh, Yuko Sakai-Tagawa, Sayaka Nagasawa, Suguru Torimitsu, Kazumi Kubota, Yuichiro Hirata, Kiyoko Iwatsuki-Horimoto, Ayumi Motomura, Namiko Ishii, Keisuke Okaba, Kie Horioka, Hiroyuki Abe, Masako Ikemura, Hirofumi Rokutan, Munetoshi Hinata, Akiko Iwasaki, Yoichi Yasunaga, Makoto Nakajima, Rutsuko Yamaguchi, Shigeki Tsuneya, Kei Kira, Susumu Kobayashi, Go Inokuchi, Fumiko Chiba, Yumi Hoshioka, Aika Mori, Isao Yamamoto, Kimiko Nakagawa, Harutaka Katano, Shun Iida, Tadaki Suzuki, Shinji Akitomi, Iwao Hasegawa, Tetsuo Ushiku, Daisuke Yajima, Hirotaro Iwase, Yohsuke Makino, Yoshihiro Kawaoka
Publikováno v:
International Journal of Infectious Diseases, Vol 129, Iss , Pp 103-109 (2023)
Objectives: The prolonged presence of infectious SARS-CoV-2 in deceased patients with COVID-19 has been reported. However, infectious virus titers have not been determined. Such information is important for public health, death investigation, and han
Externí odkaz:
https://doaj.org/article/ea332ec2822e438cacfcd58cc4f857f3
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:6455-6458
Pd-catalyzed aminocarbonylation between aryl bromide and NH-benzazepinone was effectively carried out to furnish the key intermediate for tolvaptan (up to 85%) in one step.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd7f59b61cee97720c378a3480c210c
https://doi.org/10.1016/j.bmcl.2007.09.094
https://doi.org/10.1016/j.bmcl.2007.09.094
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:2317-2320
The synthesis of 3,4-diethoxybenzthioamide, the key intermediate for OPC-6535, is achieved by employing Friedel-Crafts reaction of 1,2-diethoxybenzene with potassium thiocyanate in methanesulfonic acid at ambient temperature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4dc5ca14ff1dc8f5daa08b635c3211
https://doi.org/10.1016/s0960-894x(02)00398-0
https://doi.org/10.1016/s0960-894x(02)00398-0
Autor:
Kiyoko Iwatsuki-Horimoto, Hiroshi Ueki, Mutsumi Ito, Sayaka Nagasawa, Yuichiro Hirata, Kenichiro Hashizume, Kazuho Ushiwata, Hirotaro Iwase, Yohsuke Makino, Tetsuo Ushiku, Shinji Akitomi, Masaki Imai, Hisako Saitoh, Yoshihiro Kawaoka
Publikováno v:
mSphere, Vol 8, Iss 1 (2023)
ABSTRACT Although it has been 2.5 years since the coronavirus disease 2019 (COVID-19) pandemic began, the transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a dead infected body remains unclear, and in Japan, bereav
Externí odkaz:
https://doaj.org/article/b8971cbf9a4c4f4f8f05d578c4b853a5
Autor:
Yoshikazu Haraguchi, and Takuya Furuta, Shinji Aki, Takafumi Fujioka, Masashi Ishigami, Hiroshi Sakikawa, Jun-ichi Minamikawa
Publikováno v:
Organic Process Research & Development. 5:535-538
The fluorenone derivative (OPC-34165) has potent repairing and protecting activities for peripheral and central nervous system degeneration. A synthesis of the biphenyl-2-carboxylic acid derivative, which is the key intermediate of OPC-34165, is desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb0c96f25072685ad369fd445c12a70f
https://doi.org/10.1021/op0001279
https://doi.org/10.1021/op0001279
Autor:
Hideyuki Iwaki, Yoshiyasu Fukuyama, Mitsuaki Kodama, Shigeki Hosozawa, Shinji Aki, Yuuko Kiriyama, Kuniaki Matsui
Publikováno v:
Chemical and Pharmaceutical Bulletin. 43:1391-1394
New 1,4-benzoquinone derivatives, ardisiaquinones D(2), E(4), and F(5) along with the known ardisiaquinones A(1) and B(3) have been isolated from the leaves of Ardisia sieboldii (Myrsinaceae) and shown to be 5-lipoxygenase inhibitors. Their structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c15c4fcfd6468db59e2a9b1b289e1f2
https://doi.org/10.1248/cpb.43.1391
https://doi.org/10.1248/cpb.43.1391
Publikováno v:
Liebigs Annalen der Chemie. 1994:319-324
Tin(IV) chloride catalyzed cyclization of the epoxy olefin (±)-7 gave the octahydroazulene derivative (±)-9, the structure of which was solved by X-ray analysis of its derivative (±)-11. Titanium(IV) chloride catalyzed cyclization of the epoxy tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f91c2561b589ec1b13fd52c0da373966
https://doi.org/10.1002/jlac.199419940402
https://doi.org/10.1002/jlac.199419940402
Publikováno v:
Synthetic Communications. 23:1577-1582
The conversion of various arenediazonium salts 1 to the corresponding fluoroarenes 2 has been achieved in good yields under mild conditions in boron trifluoride diethyl ether complex.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::271beebb4b592b45214a914774d70afb
https://doi.org/10.1080/00397919308011253
https://doi.org/10.1080/00397919308011253
Publikováno v:
Liebigs Annalen der Chemie. 1993:83-90
The natural and (+)-enantiomer of 9,10-epoxytetrahydroedulan 1, (1R,3S,6R,9S,10S)-9,10-epoxy-1,3,7,7-tetramethyl-2-oxabicyclo[4.4.0]decane, the main component of the hairpencil secretion of Euploea klugii, was synthesized via (−)-dihydroedulan II (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f258991cc114bc62589494a847d0eaf6
https://doi.org/10.1002/jlac.199319930114
https://doi.org/10.1002/jlac.199319930114