Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Shinji, Sogo"'
Autor:
Fumihiro Fujiki, Soyoko Morimoto, Yuya Nishida, Satoe Tanii, Nao Aoyama, Miki Inatome, Kento Inoue, Akiko Katsuhara, Hiroko Nakajima, Jun Nakata, Sumiyuki Nishida, Akihiro Tsuboi, Yoshihiro Oka, Yusuke Oji, Shinji Sogo, Haruo Sugiyama
Publikováno v:
Cancer Immunology, Immunotherapy.
CD4+ T cells that recognize antigenic peptides presented on HLA class II are essential for inducing an optimal anti-tumor immune response, and adoptive transfer of tumor antigen-specific TCR-transduced CD4+ T cells with high responsiveness against tu
Autor:
Akihiro Tsuboi, Haruo Sugiyama, Shinji Sogo, Naoki Hosen, Kanako Imafuku, Kana Hasegawa, Sumiyuki Nishida, Soyoko Morimoto, Keiko Udaka, Kazuki Isokawa, Fumihiro Fujiki, Jun Nakata, Yusuke Oji, Hiroko Nakajima, Yoshiko Hashii, Hiromu Hayashibara, Yoshihiro Oka
Publikováno v:
Cancer Immunology, Immunotherapy. 70:3323-3335
Helper T lymphocytes (HTLs) play a central role in cancer immunity because they can not only help the induction and proliferation of cytotoxic T lymphocytes (CTLs) but also their differentiation into cytotoxic CD4+ T cells and directly kill the targe
Autor:
Naoya Hashimoto, Kana Hasegawa, Shinji Sogo, Haruo Sugiyama, Yoshihiro Oka, Yusuke Oji, Naoki Hosen, Fumihiro Fujiki, Jun Nakata, Soyoko Morimoto, Akihiro Tsuboi, Hiroko Nakajima, Sumiyuki Nishida, Miki Inatome
Publikováno v:
Cancer Immunology, Immunotherapy. 70:253-263
Simultaneous induction of tumor antigen-specific cytotoxic T lymphocytes (CTLs) and helper T lymphocytes (HTLs) is required for an optimal anti-tumor immune response. WT1332, a 16-mer WT1-derived helper peptide, induce HTLs in an HLA class II-restric
Autor:
Junji Yatsuda, Atsushi Irie, Kumiko Harada, Yayoi Michibata, Hirotake Tsukamoto, Satoru Senju, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Mohammad Abu Sayem, Naoki Takeda, Isao Shibuya, Shinji Sogo, Fumihiro Fujiki, Haruo Sugiyama, Masatoshi Eto, Yasuharu Nishimura
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84908 (2013)
Reports have shown that activation of tumor-specific CD4(+) helper T (Th) cells is crucial for effective anti-tumor immunity and identification of Th-cell epitopes is critical for peptide vaccine-based cancer immunotherapy. Although computer algorith
Externí odkaz:
https://doaj.org/article/19d69771287a45c68392bc06b1c0c833
Autor:
Hiroko, Nakajima, Jun, Nakata, Kanako, Imafuku, Hiromu, Hayashibara, Kazuki, Isokawa, Keiko, Udaka, Fumihiro, Fujiki, Soyoko, Morimoto, Kana, Hasegawa, Naoki, Hosen, Yoshiko, Hashii, Sumiyuki, Nishida, Akihiro, Tsuboi, Yoshihiro, Oka, Yusuke, Oji, Shinji, Sogo, Haruo, Sugiyama
Publikováno v:
Cancer immunology, immunotherapy : CII. 70(11)
Helper T lymphocytes (HTLs) play a central role in cancer immunity because they can not only help the induction and proliferation of cytotoxic T lymphocytes (CTLs) but also their differentiation into cytotoxic CD4
Autor:
Yasuharu Nishimura, Naoki Takeda, Shinji Sogo, Atsushi Irie, Ttatsuko Kubo, Isao Shibuya, Takahisa Imamura, Kimi Araki, Yayoi Michibata
Publikováno v:
Inflammatory bowel diseases. 23(12)
Homozygous HLA-DR4/I-E transgenic mice (tgm) spontaneously developed colitis similar to human ulcerative colitis. We explored whether endoplasmic reticulum stress in colonic epithelial cells due to overexpression of HLA-DR4/I-E was involved in the pa
Autor:
Akiko, Katsuhara, Fumihiro, Fujiki, Nao, Aoyama, Satoe, Tanii, Soyoko, Morimoto, Yoshihiro, Oka, Akihiro, Tsuboi, Hiroko, Nakajima, Kenta, Kondo, Naoya, Tatsumi, Jun, Nakata, Yoshiki, Nakae, Satoshi, Takashima, Sumiyuki, Nishida, Naoki, Hosen, Shinji, Sogo, Yusuke, Oji, Haruo, Sugiyama
Publikováno v:
Anticancer research. 35(3)
Wilms' tumor gene 1 (WT1) product is a pan-tumor-associated antigen. We previously identified WT1 protein-derived promiscuous helper peptide, WT1332. Therefore, isolation and characterization of the WT1332-specific T-cell receptors (TCRs) are useful
Publikováno v:
Blood. 128:1643-1643
Acute myeloid leukemia (AML) is the most common leukemia in older adults. Chemotherapy is the standard treatment, however, treatment efficacy and tolerability deteriorates with age, and patients are susceptible to relapse after complete remission (CR
Autor:
Shirou Fukuhara, Motoki Ito, Susumu Ikehara, Shigeru Taketani, Hiroko Hisha, Shinji Sogo, Ryuzo Sasaki, Rika Miyazaki, Yasushi Adachi, Hajime Ogata, Tomoko Iguchi, Seiji Masuda
Publikováno v:
STEM CELLS. 17:82-91
Hepatocyte growth factor (HGF) is a multifunctional cytokine with early hematopoiesis-stimulatory activity. Here, we focus on its erythropoiesis-stimulatory effect on highly purified human hematopoietic progenitor cells (CD34+/CD45+ cells) derived fr
Autor:
S Phawa, Susumu Ikehara, Shigeru Taketani, Minori Koshiji, Koshiro Hioki, Shinji Sogo, Soe Than, N Oyaizu, Muneo Inaba, Yasushi Adachi
Publikováno v:
Clinical and Experimental Immunology. 111:211-218
Fas antigen is constitutively expressed in the normal colon epithelium, but considerably diminished in most colorectal carcinomas. In the present study, we examine the relationship between Fas antigen expression and apoptosis using the colorectal car