Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shinichirou Izawa"'
Autor:
Koji Kono, Takashi Nakano, Hideki Fujii, Kazutoshi Murata, Shinichirou Izawa, Yu Ohkubo, Mitsuaki Watanabe, Yuya Yoshimoto, Kousaku Mimura, Yoshiyuki Suzuki
Although it has been shown that chemoradiotherapy may induce immunogenic cell death, which could trigger T-cell immunity mediated by high-mobility group box 1 protein (HMGB1) and calreticulin, there is still limited information to support this theory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cde73d1a33f560503b15eb9475fc4e
https://doi.org/10.1158/0008-5472.c.6504398
https://doi.org/10.1158/0008-5472.c.6504398
Autor:
Koji Kono, Takashi Nakano, Hideki Fujii, Kazutoshi Murata, Shinichirou Izawa, Yu Ohkubo, Mitsuaki Watanabe, Yuya Yoshimoto, Kousaku Mimura, Yoshiyuki Suzuki
PDF file - 58K, Maturation phenotypes of HMGB1-treated DCs by flow cytometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d77ef0adf75f298db081bd314b3bbf
https://doi.org/10.1158/0008-5472.22395776.v1
https://doi.org/10.1158/0008-5472.22395776.v1
Autor:
Koji Kono, Takashi Nakano, Hideki Fujii, Kazutoshi Murata, Shinichirou Izawa, Yu Ohkubo, Mitsuaki Watanabe, Yuya Yoshimoto, Kousaku Mimura, Yoshiyuki Suzuki
PDF file - 203K, Surface expression of calreticulin on TE2 after 30Gy-irradiation (10Gy irradiation on day 1, day 2, and day 3) or chemotherapy (5FU + CDDP + Docetaxel on day 1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b140dc32bbb84e8d6b71532211ecd0
https://doi.org/10.1158/0008-5472.22395779
https://doi.org/10.1158/0008-5472.22395779
Autor:
Koji Kono, Takashi Nakano, Hideki Fujii, Kazutoshi Murata, Shinichirou Izawa, Yu Ohkubo, Mitsuaki Watanabe, Yuya Yoshimoto, Kousaku Mimura, Yoshiyuki Suzuki
PDF file - 50K, Correlation of serum HMGB1 level with grade of antigen-specific T cell responses (Spot-forming cells) by ELISPOT assay against each antigen in patients receiving chemoradiotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c677478fc8704864e9957d501f805ab
https://doi.org/10.1158/0008-5472.22395785
https://doi.org/10.1158/0008-5472.22395785
Autor:
Takanori Maruyama, Koji Kono, Kousaku Mimura, Mitsuaki Watanabe, Hideki Fujii, Yoshihiko Kawaguchi, Shinichirou Izawa
Publikováno v:
Cancer Immunology, Immunotherapy. 62:161-170
Although an increase in regulatory T cells (Tregs) is observed in tumor microenvironments, the underlying mechanism is not fully clarified. Since it was suggested that Tregs showed a lower sensitivity toward oxidative stress in comparison with conven
Autor:
Shinichirou Izawa, Mitsuaki Watanabe, Koji Kono, Takanori Maruyama, Yoshihiko Kawaguchi, Hideki Fujii, Kousaku Mimura
Publikováno v:
Cancer Immunology, Immunotherapy. 60:1801-1810
Human NK cells can be divided into two subsets, CD56dimCD16(+)NK and CD56brightCD16(−)NK cells, based on their expression of CD56 and CD16. In the present study, we analyzed the relationship between CD56dim/CD56bright NK cells and H2O2 in tumor-inf
Autor:
Yoshihiko Kawaguchi, Hideki Fujii, Kosaku Mimura, Mitsuaki Watanabe, Shinichirou Izawa, Takanori Maruyama, Koji Kono, Yoshiki Mizukami
Publikováno v:
Diseases of the Esophagus. 23:675-681
NK cells can be divided into two subsets, CD56(dim) and CD56(bright) NK cells, based on their expression of CD56 and CD16. In the present study, we analyzed NK cell dysfunction in patients with esophageal squamous cell carcinoma (ESCC), with a partic
Autor:
Yoshiki Mizukami, Hideki Fujii, Kousaku Mimura, Koji Kono, Mitsuaki Watanabe, Takanori Maruyama, Yoshihiko Kawaguchi, Shinichirou Izawa
Publikováno v:
Cancer Science. 101:1947-1954
Although Th17 cells reportedly play critical roles in the development of autoimmunity and allergic reactions, information on Th17 cells in cancer-bearing hosts is still limited. In the present study, we investigated the distribution of Th17 cells in
Autor:
Shinichirou, Izawa, Koji, Kono, Kousaku, Mimura, Yoshihiko, Kawaguchi, Mitsuaki, Watanabe, Takanori, Maruyama, Hideki, Fujii
Publikováno v:
Cancer immunology, immunotherapy : CII. 60(12)
Human NK cells can be divided into two subsets, CD56(dim)CD16(+)NK and CD56(bright)CD16(-)NK cells, based on their expression of CD56 and CD16. In the present study, we analyzed the relationship between CD56(dim)/CD56(bright) NK cells and H₂O₂ in
Autor:
Yoshihiko Kawaguchi, Shinichirou Izawa, Yoshiki Mizukami, Mitsuaki Watanabe, Hideki Fujii, Koji Kono, Kousaku Mimura, Takanori Maruyama
Publikováno v:
Diseases of the Esophagus.
It has been reported that an increased population of regulatory T cells (T-regs) is one of the reasons for impaired anti-tumor immunity. We investigated the frequency of Foxp3(+) T-regs in tumor-infiltrating lymphocytes (TILs) and peripheral blood ly