Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shinichiro Niwa"'
Autor:
Shinichiro Niwa, Natsuko Utsunomiya, Minoru Hasegawa, Yoko Sasaki, V.H. Luong, Takenao Chino, Noritaka Oyama, Dai Ogura, Takashi Matsushita, Akira Utsunomiya
BackgroundSystemic sclerosis (SSc) is a collagen disease that exhibits intractable fibrosis and vascular injury of the skin and internal organs. Transforming growth factor-β (TGF-β)/Smad signaling plays a central role in extracellular matrix (ECM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cec449c258432d4f4e93bff7f29b403c
https://doi.org/10.21203/rs.3.rs-529685/v1
https://doi.org/10.21203/rs.3.rs-529685/v1
Blockade of TGF-β/Smad signaling by the small compound HPH-15 ameliorates experimental skin fibrosis
Autor:
Mikako Fujita, Noritaka Oyama, Takashi Matsushita, Hironobu Ihn, Minoru Hasegawa, Takenao Chino, Yoko Sasaki, V.H. Luong, Akiyuki Hamasaki, Tanima Biswas, Dai Ogura, Shinichiro Niwa, Masami Otsuka, Yoshinari Okamoto
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-13 (2018)
Arthritis Research & Therapy
Arthritis Research & Therapy
Background Transforming growth factor-β (TGF-β)/Smad signaling is well known to play a critical role in the pathogenesis of systemic sclerosis (SSc). We previously developed an artificial molecule, the histidine-pyridine-histidine ligand derivative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0672799574d88c35e8f7166066b4acb
http://link.springer.com/article/10.1186/s13075-018-1534-y
http://link.springer.com/article/10.1186/s13075-018-1534-y
Autor:
Koichiro Niwa, Kazuhiro Sakamoto, Yutaka Kojima, Kiichi Nagayasu, Yuichi Tomiki, Hiromitsu Komiyama, Kiichi Sugimoto, Yoshihiko Tashiro, Rina Takahashi, Shun Ishiyama, Michitoshi Goto, Shinichiro Niwa, Dai Ogura
Publikováno v:
Molecular and Clinical Oncology
The aim of this study was to evaluate the impact of laparoscopic surgery (Lap) on circulating free tumor cells in colorectal cancer patients. In this study, we selected carcinoembryonic antigen (CEA) mRNA expression in peripheral blood as the marker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa806b45cf946b6e20dbd1b6fe6c69bb
http://europepmc.org/articles/PMC3915518
http://europepmc.org/articles/PMC3915518
Autor:
Haruna Ishida, Masayuki Kobayashi, Tohru Tanizawa, Yukio Nakatani, Koji Kawamura, Hiroyoshi Suzuki, Taizo Shiraishi, Takayuki Shindo, Yoshifumi Hirokawa, Naoto Kamiya, Shinichiro Niwa, Tomohiko Ichikawa, Mika Kino, Takashi Imamoto
Publikováno v:
The Prostate. 68:1715-1724
BACKGROUND Prostate cancer is often multifocal and shows histological heterogeneity among different tumor foci within the same prostate. We analyzed the origin and molecular basis of multifocal prostate cancer and genomic alterations associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee755cb6bc408bb6971e5b8ab009cf8b
https://doi.org/10.1002/pros.20832
https://doi.org/10.1002/pros.20832
Autor:
Takayuki Shindo, Yukihiro Yaginuma, Jo Unotoro, Kazuhiro Sakamoto, Toshiki Kamano, Hirohiko Kamiyama, Yasunori Ishido, Shinichiro Niwa, Shinji Kasamaki
Publikováno v:
Nihon Gekakei Rengo Gakkaishi (Journal of Japanese College of Surgeons). 30:831-835
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fec8495a0aed322edcea9dc2cc5c5e2f
https://doi.org/10.4030/jjcs1979.30.6_831
https://doi.org/10.4030/jjcs1979.30.6_831
Autor:
Savitri Krishnamurthy, James Tepperberg, Wendy A. Woodward, Wei Yang, Ricardo H. Alvarez, Naoto T. Ueno, Yun Gong, James M. Reuben, Vicente Valero, Randa El-Zein, Ana M. Gonzalez-Angulo, Shinichiro Niwa, Lei Huo, Dai Ogura, Mariana Chavez-MacGregor, Anthony Lucci
Publikováno v:
SpringerPlus
Background Although preliminary reports suggest that ALK gene amplification may occur in inflammatory breast cancer (IBC), data are limited. We performed a comprehensive investigation of the status of ALK gene in IBC. Methods We used core biopsy (CB)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e919aef3c6a0d0c9dbb480db990e539c
https://doi.org/10.1186/2193-1801-2-409
https://doi.org/10.1186/2193-1801-2-409
Publikováno v:
The Journal of Cell Biology
Hepatocyte growth factor (HGF) and EGF have been reported to promote branching morphogenesis of mammary epithelial cells. We now show that it is epimorphin that is primarily responsible for this phenomenon. In vivo, epimorphin was detected in the str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ff92bde5ce4ae9e05d5aabe8aab24e
https://pubmed.ncbi.nlm.nih.gov/9425164
https://pubmed.ncbi.nlm.nih.gov/9425164
Autor:
Kazuhiro Sakamoto, Yuichi Tomiki, Masanobu Tanaka, Shinichiro Niwa, Hironobu Sengoku, Michitoshi Goto
Publikováno v:
Journal of Minimal Access Surgery, Vol 3, Iss 3, Pp 98-103 (2007)
Journal of Minimal Access Surgery
Journal of Minimal Access Surgery
Purpose: Obesity has been generally associated with increased surgical risk. However, data on the outcome of laparoscopic colectomy in obese and non-obese patients are controversial. The aim of this study is to assess the short-term outcome of laparo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aaeb56989f3bdbeb67a36d12ab85ca3
https://doi.org/10.4103/0972-9941.37192
https://doi.org/10.4103/0972-9941.37192
Autor:
Masataka Sugimoto1,2, Takeshi Nakamura3, Naoko Ohtani1, Lynne Hampson4, Hampson, Ian N.4, Akira Shimamoto5, Yasuhiro Furuichi5, Ko Okumura2, Shinichiro Niwa3, Yoichi Taya6, Eiji Hara1 Ehara@picr.man.ac.uk
Publikováno v:
Genes & Development. 2015, Vol. 29 Issue 22, p3027-3033. 7p.