Zobrazeno 1 - 10
of 320
pro vyhledávání: '"Shinichiro HAYASHI"'
Autor:
Takuya Nagata, Tadaaki Satou, Shinichiro Hayashi, Prabodh Satyal, Manabu Watanabe, Brannick Riggs, Yoshihisa Saida
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Objective Although cancer therapy suppresses recurrence and prolongs life, it may be accompanied by strong side effects; thus, there is a strong demand for the development effective treatments with fewer side effects. Cancer therapy using pl
Externí odkaz:
https://doaj.org/article/c5eb0ab0ec1645c6bcd43b3cb3ab4e95
Autor:
Wakako Yoshioka, Aritoshi Iida, Kyuto Sonehara, Kazuki Yamamoto, Yasushi Oya, Madoka Mori-Yoshimura, Takashi Kurashige, Mariko Okubo, Megumu Ogawa, Fumihiko Matsuda, Koichiro Higasa, Shinichiro Hayashi, Harumasa Nakamura, Masakazu Sekijima, Yukinori Okada, Satoru Noguchi, Ichizo Nishino
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract GNE myopathy is a distal myopathy caused by biallelic variants in GNE, which encodes a protein involved in sialic acid biosynthesis. Compound heterozygosity of the second most frequent variant among Japanese GNE myopathy patients, GNE c.620A
Externí odkaz:
https://doaj.org/article/4f9dabf851b449cc98ef9808181bb5ac
Autor:
Masashi Ogasawara, Nobuyuki Eura, Aritoshi Iida, Theerawat Kumutpongpanich, Narihiro Minami, Ikuya Nonaka, Shinichiro Hayashi, Satoru Noguchi, Ichizo Nishino
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-7 (2022)
Abstract Oculopharyngodistal myopathy (OPDM) and oculopharyngeal muscular dystrophy (OPMD) are similar and even believed to be indistinguishable in terms of their myopathological features. To address the diagnostic gap, we evaluated the muscle biopsy
Externí odkaz:
https://doaj.org/article/bf430c0312ca4de89b480b931a09d9f1
Autor:
Yosuke Hiramuki, Yuriko Kure, Yoshihiko Saito, Megumu Ogawa, Keiko Ishikawa, Madoka Mori-Yoshimura, Yasushi Oya, Yuji Takahashi, Dae-Seong Kim, Noriko Arai, Chiaki Mori, Tsuyoshi Matsumura, Tadanori Hamano, Kenichiro Nakamura, Koji Ikezoe, Shinichiro Hayashi, Yuichi Goto, Satoru Noguchi, Ichizo Nishino
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant muscular disorder characterized by asymmetric muscle wasting and weakness. FSHD can be subdivided into two types: FSHD1, caused by contraction of the D4Z4 repe
Externí odkaz:
https://doaj.org/article/232b7b90ca3f41728eb543822e9d6aba
Publikováno v:
Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, Vol 16 (2022)
BACKGROUND Chronic obstructive pulmonary disease (COPD) is accompanied by dyspnea on exertion due to airflow limitation caused by bronchial stenosis, with afflicted patients being less physically active. Therefore, physical activity is important for
Externí odkaz:
https://doaj.org/article/db7077b135e54143b5c97c7f9c0bc89d
Publikováno v:
SAGE Open Medicine, Vol 9 (2021)
Objectives: Research on the determinants of physical activity in mildly symptomatic patients with chronic obstructive pulmonary disease is lacking. This study examined the predictors of physical activity in patients with low-risk chronic obstructive
Externí odkaz:
https://doaj.org/article/f2ca0bb0647345f7921b9fc447b16b0f
Autor:
Pedro Vallecillo-García, Mickael Orgeur, Sophie vom Hofe-Schneider, Jürgen Stumm, Verena Kappert, Daniel M. Ibrahim, Stefan T. Börno, Shinichiro Hayashi, Frédéric Relaix, Katrin Hildebrandt, Gerhard Sengle, Manuel Koch, Bernd Timmermann, Giovanna Marazzi, David A. Sassoon, Delphine Duprez, Sigmar Stricker
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Fibro-adipogenic progenitors (FAPs) form part of interstitial muscle connective tissue (MCT) in adults but the origin of this non-myogenic lineage is unclear. Here, the authors show that Odd skipped related 1 (Osr1) in mice marks embryonic MCT, givin
Externí odkaz:
https://doaj.org/article/1e034f7aaeb14e40b5bb3d020e082645
Autor:
Yumiko Oishi, Shinichiro Hayashi, Takayuki Isagawa, Motohiko Oshima, Atsushi Iwama, Shigeki Shimba, Hitoshi Okamura, Ichiro Manabe
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Bmal1 (encoded by Arntl gene) is a core circadian clock gene that regulates various genes involved in circadian rhythm. Although Bmal1 is expressed rhythmically in macrophages, the role of Bmal1 in the regulation of their cellular function r
Externí odkaz:
https://doaj.org/article/10d6195f143947fcb71cc8c42af95a51
Autor:
Isabella Scionti, Shinichiro Hayashi, Sandrine Mouradian, Emmanuelle Girard, Joana Esteves de Lima, Véronique Morel, Thomas Simonet, Maud Wurmser, Pascal Maire, Katia Ancelin, Eric Metzger, Roland Schüle, Evelyne Goillot, Frederic Relaix, Laurent Schaeffer
Publikováno v:
Cell Reports, Vol 18, Iss 8, Pp 1996-2006 (2017)
MyoD is a master regulator of myogenesis. Chromatin modifications required to trigger MyoD expression are still poorly described. Here, we demonstrate that the histone demethylase LSD1/KDM1a is recruited on the MyoD core enhancer upon muscle differen
Externí odkaz:
https://doaj.org/article/df842c1b9ad94a8c89dc918ed4dc92ec
Autor:
Yohei Imamura, Tomotaka Kawayama, Takashi Kinoshita, Yuki Sakazaki, Makoto Yoshida, Koichiro Takahashi, Kazuhiko Fujii, Masaru Ando, Tomoaki Hoshino, Tomoaki Iwanaga, Hirotsugu Kohrogi, Yoichi Nakanishi, Hiroshi Mukae, Kentaro Watanabe, Shinichiro Hayashi, Junichi Kadota, Toshihiko Ii, Hiromasa Inoue, Takao Tochigi, Jiro Fujita, Hiroshi Nakamura
Publikováno v:
Allergology International, Vol 66, Iss 3, Pp 482-484 (2017)
Externí odkaz:
https://doaj.org/article/f193817b180349e2b4f33e57a332944b