Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shinichiro, Tajiri"'
Publikováno v:
Molecular Pharmaceutics. 12:966-973
A major barrier to successful oral delivery of peptide and protein molecules is their inherent instability in the lumen of the gastrointestinal tract. The aim of this study was to determine the stability of 17 disparate peptide drugs (insulin, calcit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa6b9786c8a638487b67db2c9f9e8a9
https://doi.org/10.1021/mp500809f
https://doi.org/10.1021/mp500809f
Autor:
Shuichi Yada, Tsutomu Konno, Hiroaki Nakagami, Sachiko Fukui, Taro Kanamaru, Shinichiro Tajiri, Kazuhiro Yoshida, Yasue Hosoi
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 75:238-244
The purpose of this study was to develop a new method using beagle dogs in order to evaluate the colonic absorption properties of oral extended-release (ER) solid dosage forms. The established method is not only noninvasive and inexpensive but full-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a65e8df3f25f1c78efb766e88bb86d
https://doi.org/10.1016/j.ejpb.2010.03.009
https://doi.org/10.1016/j.ejpb.2010.03.009
Autor:
Shinichiro, Tajiri, Taro, Kanamaru, Makoto, Kamada, Kamada, Makoto, Tsutomu, Konno, Hiroaki, Nakagami
Publikováno v:
International Journal of Pharmaceutics. 383:99-105
The objective of the present work is to develop an extended-release dosage form of cevimeline. Two types of extended-release tablets (simple matrix tablets and press-coated tablets) were prepared and their potential as extended-release dosage forms w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33b982a2cafafefb6d6f0f34a95f9a8
https://doi.org/10.1016/j.ijpharm.2009.09.007
https://doi.org/10.1016/j.ijpharm.2009.09.007
Publikováno v:
Journal of Drug Delivery Science and Technology. 20:213-218
Extended-release tablets (ER) of cevimeline hydrochloride were prepared and in vivo absorptions following oral administration to beagle dogs were investigated. These in vivo studies were conducted with or without taking into account the gastrointesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::667d72715995cadcf9f1d120176f869d
https://doi.org/10.1016/s1773-2247(10)50032-7
https://doi.org/10.1016/s1773-2247(10)50032-7
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 78
This study was the first to investigate the colonic stability of 17 peptide molecules (insulin, calcitonin, glucagon, secretin, somatostatin, desmopressin, oxytocin, Arg-vasopressin, octreotide, ciclosporin, leuprolide, nafarelin, buserelin, histreli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bd0d84f37a5e0427cc37302f00039c
https://pubmed.ncbi.nlm.nih.gov/26111980
https://pubmed.ncbi.nlm.nih.gov/26111980
Autor:
Hiroaki Nakagami, Shuichi Yada, Taro Kanamaru, Tsutomu Konno, Yasue Hosoi, Kazuhiro Yoshida, Shinichiro Tajiri
Publikováno v:
Chemicalpharmaceutical bulletin. 58(10)
After the dosing of an extended-release (ER) formulation, compounds may exist in solutions at various concentrations in the colon because the drugs are released at various speeds from the ER dosage form. The aim of this study was to investigate the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f0115a49cc7fdc4b1a328ae2da1b9c
https://pubmed.ncbi.nlm.nih.gov/20930393
https://pubmed.ncbi.nlm.nih.gov/20930393
Publikováno v:
Pharmaceutical research. 21(12)
To evaluate the effect of hydrophilic cyclodextrins (CyDs) on the aggregation induced by different stresses and on the oxidation and deamidation of recombinant human growth hormone (rhGH).The aggregation of rhGH was induced by three denaturing techni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2c1c30146e8f2102cda6c28f52a37f
https://pubmed.ncbi.nlm.nih.gov/15648271
https://pubmed.ncbi.nlm.nih.gov/15648271
Publikováno v:
International Journal of Pharmaceutics. 399:173
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::763d5b781d08d952c24f78e36e74a5b2
https://doi.org/10.1016/j.ijpharm.2010.08.001
https://doi.org/10.1016/j.ijpharm.2010.08.001
Autor:
Hiroki Kikuchi, Yoshiyuki Akiyama, Tsuneo Hayashi, Akira Nakamura, Michio Oka, Yutaka Sugawara, Shinichiro Tajiri, Naoya Eguchi, Shigeki Hashimoto
Publikováno v:
Information Display. 25:31-31
— A high-pixel-rate, high-contrast (30,000:1) wide-color-gamut grating-light-valve laser projector is reported. A new optical engine enabling high-frame-rate (240 Hz) scan projection is employed. Panoramic wide-angle-scan projection with a 64:9 asp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6d5e69265daf4562aa8e38874ac2e5
https://doi.org/10.1002/j.2637-496x.2009.tb00074.x
https://doi.org/10.1002/j.2637-496x.2009.tb00074.x
Autor:
Shinichiro Tajiri, Tsuneo Hayashi, Naoya Eguchi, Michio Oka, Yutaka Sugawara, Hiroki Kikuchi, Yoshiyuki Akiyama, Shigeki Hashimoto, Akira Nakamura
Publikováno v:
SID Symposium Digest of Technical Papers. 39:846
We report a high frame rate (240Hz), high contrast (30,000:1), wide color gamut GxL (G-by-L) laser projector. Proposed application areas for GxL are also discussed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fd68ada378841346570d521aa15c961
https://doi.org/10.1889/1.3069803
https://doi.org/10.1889/1.3069803