Zobrazeno 1 - 10
of 456
pro vyhledávání: '"Shinichi UCHIDA"'
Autor:
Yuta Nakano, Shintaro Mandai, Daiei Takahashi, Ken Ikenouchi, Yutaro Mori, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Kiyohide Fushimi, Shinichi Uchida
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110577- (2024)
Summary: The global outcome of acute aortic dissection (AD) remains poor, with a high risk of the need for urgent dialysis. This study aimed to clarify the association between sex and the requirement for urgent dialysis within 30 days after admission
Externí odkaz:
https://doaj.org/article/52c4d0524b10407bb841120b345a940f
Autor:
Ken Ikenouchi, Daiei Takahashi, Shintaro Mandai, Mizuki Watada, Sayumi Koyama, Motoki Hoshino, Naohiro Takahashi, Wakana Shoda, Tamaki Kuyama, Yutaro Mori, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Kiyohide Fushimi, Shinichi Uchida
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Coronavirus disease 2019 (COVID-19) affects both life and health. However, the differentiation from other types of pneumonia and effect of kidney disease remains uncertain. This retrospective observational study investigated the risk of in-h
Externí odkaz:
https://doaj.org/article/1539edfff1c74f5b9ca2f8f76476cc12
Autor:
Misa Hata, Takayasu Mori, Yurika Hirose, Yuriko Nishida, Shintaro Mandai, Fumiaki Ando, Koichiro Susa, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Tatemitsu Rai, Towako Taguchi, Shohei Tomii, Kenichi Ohashi, Shinichi Uchida
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-6 (2024)
Abstract Fibronectin (FN) glomerulopathy (FNG), a rare autosomal hereditary renal disease, is characterized by proteinuria resulting from the massive accumulation of FN in the glomeruli. It typically affects individuals aged 10–50 years. In this re
Externí odkaz:
https://doaj.org/article/17e22ae0bef5490582eebc7e79569bba
Autor:
Yutaro Ohno, Eri Okita, Mika Kawai-Uchida, Youji Shoukei, Kazuhiro Soshiroda, Tomoyuki Kanda, Shinichi Uchida
Publikováno v:
Journal of Pharmacological Sciences, Vol 152, Iss 3, Pp 193-199 (2023)
The adenosine A2A receptor antagonist/inverse agonist, KW-6356 has been shown to be effective in Parkinson's disease (PD) patients as monotherapy and as an adjunct therapy to L-3,4-dihydroxyphenylalanine (L-DOPA)/decarboxylase inhibitor. However, the
Externí odkaz:
https://doaj.org/article/c813e07e2733429a92c3bfbdfcba0ff4
Autor:
Nobuhisa Morimoto, Takayasu Mori, Shingo Shioji, Towako Taguchi, Hatsumi Watanabe, Keigo Sakai, Katsuo Mori, Ayumi Yamamura, Asami Hanioka, Yuichiro Akagi, Tamami Fujiki, Shintaro Mandai, Yutaro Mori, Fumiaki Ando, Koichiro Susa, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Kenichi Ohashi, Shinichi Uchida
Publikováno v:
BMC Nephrology, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background As messenger RNA (mRNA)-based vaccines for coronavirus disease 2019 (COVID-19) have been administered to millions of individuals worldwide, cases of de novo and relapsing glomerulonephritis after mRNA COVID-19 vaccination are incr
Externí odkaz:
https://doaj.org/article/f877adac4c2945cbb0eb5679ab5e0cdc
Autor:
Soichiro Suzuki, Fumiaki Ando, Sae Kitagawa, Yu Hara, Tamami Fujiki, Shintaro Mandai, Koichiro Susa, Takayasu Mori, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
ZNF185 is identified as a novel PKA substrate and found to be important for the organization of endothelial cell–cell junctions and suppression of vascular hyperpermeability by regulating the cAMP/PKA/RhoA signaling pathway.
Externí odkaz:
https://doaj.org/article/8f63103e0820459da3615d3e0e88138a
Autor:
Maho Hatano, Tomohiro Udagawa, Toru Kanamori, Akito Sutani, Takayasu Mori, Eisei Sohara, Shinichi Uchida, Tomohiro Morio, Masato Nishioka
Publikováno v:
Human Genome Variation, Vol 9, Iss 1, Pp 1-3 (2022)
Abstract Familial renal glucosuria (FRG) is characterized by persistent glucosuria despite normal blood glucose levels in the absence of overt tubular dysfunction. SGLT2 is a sodium-glucose cotransporter expressed in the proximal tubule; loss-of-func
Externí odkaz:
https://doaj.org/article/39d1fb9036b84b10b71a75840737e8d7
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
With-no-lysine (K) (WNK) kinases have been identified as the causal genes for pseudohypoaldosteronism type II (PHAII), a rare hereditary hypertension condition characterized by hyperkalemia, hyperchloremic metabolic acidosis, and thiazide-hypersensit
Externí odkaz:
https://doaj.org/article/980efa95f62145dab73b59f3e2026588
Autor:
Ryohei Miyamoto, Akinari Sekine, Takuya Fujimaru, Tatsuya Suwabe, Hiroki Mizuno, Eiko Hasegawa, Masayuki Yamanouchi, Motoko Chiga, Takayasu Mori, Eisei Sohara, Shinichi Uchida, Naoki Sawa, Yoshifumi Ubara, Junichi Hoshino
Publikováno v:
Kidney Diseases, Pp 1-7 (2021)
Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary cystic kidney disease and is well known to have extrarenal complications. Cardiovascular complications are of particular clinical relevance because of thei
Externí odkaz:
https://doaj.org/article/20159581ebd24ead92911dd6a7f85b82
Autor:
Adya Saran Sinha, Tianying Wang, Miho Watanabe, Yasushi Hosoi, Eisei Sohara, Tenpei Akita, Shinichi Uchida, Atsuo Fukuda
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The with-no-lysine (WNK) family of serine-threonine kinases and its downstream kinases of STE20/SPS1-related proline/alanine-rich kinase (SPAK) and oxidative stress-responsive kinase-1 (OSR1) may regulate intracellular Cl− homeostasis through phosp
Externí odkaz:
https://doaj.org/article/3e1185f64de744b69d71d7b650f7dd6f