Zobrazeno 1 - 10
of 1 572
pro vyhledávání: '"Shinichi SATO"'
Autor:
Lixin Li, Satoshi Toyama, Yuka Mizuno, Toyoki Yamamoto, Asahi Hiroshima, Asumi Koyama, Haruka Taira, Eiki Sugimoto, Yukiko Ito, Kentaro Awaji, Shoko Tateishi, Hiroko Kanda, Yoshihide Asano, Shinichi Sato, Sayaka Shibata
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Psoriasis is a chronic inflammatory disease that sometimes necessitates therapeutic intervention with biologics. Autoantibody production during treatment with tumor necrosis factor (TNF) inhibitors is a recognized phenomenon, however, the pr
Externí odkaz:
https://doaj.org/article/7d6eb6ae46794f36a967b28a8e7cc02e
Autor:
Takemichi Fukasawa, Asako Yoshizaki-Ogawa, Atsushi Enomoto, Takashi Yamashita, Kiyoshi Miyagawa, Shinichi Sato, Ayumi Yoshizaki
Publikováno v:
Immunological Medicine, Vol 47, Iss 3, Pp 118-129 (2024)
In recent years, rapid advances in research methods have made single cell analysis possible. Systemic sclerosis (SSc), a disease characterized by the triad of immune abnormalities, fibrosis, and vasculopathy, has also been the subject of various anal
Externí odkaz:
https://doaj.org/article/f664c7198108499d86ead80897256255
Publikováno v:
Journal of Cutaneous Immunology and Allergy, Vol 7 (2024)
Externí odkaz:
https://doaj.org/article/5f51c073a7254513a81caaeaa823e16d
Autor:
Ayaka Sugimori, Issei Omori, Okuto Iwasawa, Hinako Saito, Hibari Nakajima, Ai Matsuno, Shinichi Sato, Hayakazu Sumida
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Systemic sclerosis (SSc) is a connective tissue disease characterized by aberrant immune activation, vascular injury, and fibrosis of the skin and internal organs. Ly6/PLAUR domain-containing protein 1 (LYPD1) was reported to be secreted and
Externí odkaz:
https://doaj.org/article/19bd6a58f95b483681ba3fc4bbc367af
Autor:
Atsushi Enomoto, Takemichi Fukasawa, Hiroshi Terunuma, Keiichi Nakagawa, Ayumi Yoshizaki, Shinichi Sato, Noriko Hosoya, Kiyoshi Miyagawa
Publikováno v:
International Journal of Hyperthermia, Vol 41, Iss 1 (2024)
AbstractPurpose c-Jun N-terminal kinases (JNKs) comprise a subfamily of mitogen-activated protein kinases (MAPKs). The JNK group is known to be activated by a variety of stimuli. However, the molecular mechanism underlying heat-induced JNK activation
Externí odkaz:
https://doaj.org/article/9386758602e74631bb78906ebd21bea5
Publikováno v:
Acta Dermato-Venereologica, Vol 104 (2024)
Abstract is missing (Short communication)
Externí odkaz:
https://doaj.org/article/071dd1e0bcad40b0ae806b0c4feb81aa
Autor:
Yuki Ishikawa, Nao Tanaka, Yoshihide Asano, Masanari Kodera, Yuichiro Shirai, Mitsuteru Akahoshi, Minoru Hasegawa, Takashi Matsushita, Kazuyoshi Saito, Sei-ichiro Motegi, Hajime Yoshifuji, Ayumi Yoshizaki, Tomohiro Kohmoto, Kae Takagi, Akira Oka, Miho Kanda, Yoshihito Tanaka, Yumi Ito, Kazuhisa Nakano, Hiroshi Kasamatsu, Akira Utsunomiya, Akiko Sekiguchi, Hiroaki Niiro, Masatoshi Jinnin, Katsunari Makino, Takamitsu Makino, Hironobu Ihn, Motohisa Yamamoto, Chisako Suzuki, Hiroki Takahashi, Emi Nishida, Akimichi Morita, Toshiyuki Yamamoto, Manabu Fujimoto, Yuya Kondo, Daisuke Goto, Takayuki Sumida, Naho Ayuzawa, Hidetoshi Yanagida, Tetsuya Horita, Tatsuya Atsumi, Hirahito Endo, Yoshihito Shima, Atsushi Kumanogoh, Jun Hirata, Nao Otomo, Hiroyuki Suetsugu, Yoshinao Koike, Kohei Tomizuka, Soichiro Yoshino, Xiaoxi Liu, Shuji Ito, Keiko Hikino, Akari Suzuki, Yukihide Momozawa, Shiro Ikegawa, Yoshiya Tanaka, Osamu Ishikawa, Kazuhiko Takehara, Takeshi Torii, Shinichi Sato, Yukinori Okada, Tsuneyo Mimori, Fumihiko Matsuda, Koichi Matsuda, Tiffany Amariuta, Issei Imoto, Keitaro Matsuo, Masataka Kuwana, Yasushi Kawaguchi, Koichiro Ohmura, Chikashi Terao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Here we report the largest Asian genome-wide association study (GWAS) for systemic sclerosis performed to date, based on data from Japanese subjects and comprising of 1428 cases and 112,599 controls. The lead SNP is in the FCGR/FCRL region,
Externí odkaz:
https://doaj.org/article/2821292baef747248e9e487cef06ad07
Autor:
Yukiko Ito, Sayaka Shibata, Asumi Koyama, Lixin Li, Eiki Sugimoto, Haruka Taira, Yuka Mizuno, Kentaro Awaji, Shinichi Sato
Publikováno v:
Journal of Cutaneous Immunology and Allergy, Vol 6, Iss 6, Pp 208-218 (2023)
Abstract Background Psoriasis is a chronic skin inflammatory disease characterized by epidermal proliferation and inflammatory cell infiltration. AXL is a tyrosine kinase receptor that promotes cell proliferation and invasion in cancer cells, and its
Externí odkaz:
https://doaj.org/article/a2cff9db68494a4d82aec8a4af20b0ae
Autor:
Issei Omori, Hayakazu Sumida, Ayaka Sugimori, Moe Sakakibara, Mariko Urano-Takaoka, Okuto Iwasawa, Hinako Saito, Ai Matsuno, Shinichi Sato
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Systemic sclerosis (SSc) is a complex autoimmune disease characterized by fibrotic, inflammatory, and vascular dysfunction. Danger-associated molecular patterns (DAMPs)-mediated inflammasome activation has been reported to be involved in the
Externí odkaz:
https://doaj.org/article/c893dbff6d7345c7b79652ab8cf152ab
Autor:
Takemichi Fukasawa, Takashi Yamashita, Atsushi Enomoto, Yuta Norimatsu, Satoshi Toyama, Asako Yoshizaki-Ogawa, Shoko Tateishi, Hiroko Kanda, Kiyoshi Miyagawa, Shinichi Sato, Ayumi Yoshizaki
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAs a form of precision medicine, this study aimed to investigate the specific patient population that would derive the greatest benefit from tildrakizumab, as well as the mechanism of action and efficacy of tildrakizumab in reducing the o
Externí odkaz:
https://doaj.org/article/1e561e98a9c44454a0271abeeb46dfad