Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Shinichi Nakamuta"'
Autor:
Tetsuya Takano, Mengya Wu, Shinichi Nakamuta, Honda Naoki, Naruki Ishizawa, Takashi Namba, Takashi Watanabe, Chundi Xu, Tomonari Hamaguchi, Yoshimitsu Yura, Mutsuki Amano, Klaus M. Hahn, Kozo Kaibuchi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Emerging evidence suggests that gut microbiota influences immune function in the brain and may play a role in neurological diseases. Here, the authors offer in vivo evidence from a Drosophila model that supports a role for gut microbiota in modulatin
Externí odkaz:
https://doaj.org/article/499fc341abbe4dc59222498325b5f835
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19034 (2011)
Polarization, a disruption of symmetry in cellular morphology, occurs spontaneously, even in symmetrical extracellular conditions. This process is regulated by intracellular chemical reactions and the active transport of proteins and it is accompanie
Externí odkaz:
https://doaj.org/article/aa9fd00e82384b4ab1d8277682509548
Autor:
Yukie Yamahashi, Naoto Yukinawa, Kiyofumi Yamada, Shinichi Nakamuta, Taku Nagai, Xinjian Zhang, Keisuke Kuroda, Kozo Kaibuchi, Mutsuki Amano, Rijwan Uddin Ahammad, Yasuhiro Funahashi, Junichiro Yoshimoto, Takashi Nakano
Publikováno v:
Neurochemistry International. 122:8-18
Medium spiny neurons (MSNs) expressing dopamine D1 receptor (D1R) or D2 receptor (D2R) are major components of the striatum. Stimulation of D1R activates protein kinase A (PKA) through Golf to increase neuronal activity, while D2R stimulation inhibit
Autor:
Yilin Tai, Nicholas B. Gallo, Jia Ray Yu, Shinichi Nakamuta, Yu-Ting Yang, Chia-Lin Wang, Linda Van Aelst
Publikováno v:
The Journal of Cell Biology
Neuroblasts born postnatally in the ventricular–subventricular zone migrate long distances via the rostral migratory stream (RMS) to the olfactory bulb. Nakamuta et al. show that DOCK7 drives tangential migration of neuroblasts in the RMS by contro
Autor:
Hiroshi Kiyama, Kumiko Makide, Tomohiko Ohwada, Junken Aoki, Shinichi Nakamuta, Hiroyuki Konishi, Kozo Kaibuchi, Kyohei Tokizane, Hiroki Kawana
Publikováno v:
Glia. 65:740-755
Under a quiescent state, microglia exhibit a ramified shape, rather than the amoeboid-like morphology following injury or inflammation. The manipulation of microglial morphology in vitro has not been very successful, which has impeded the progress of
Autor:
Masami Miura, Yasuhiro Funahashi, Masahiko Watanabe, Taku Nagai, Tomoki Nishioka, Motokazu Uchigashima, Junichiro Yoshimoto, Xinjian Zhang, Keisuke Kuroda, Kiyofumi Yamada, Tetsuya Takano, Daisuke Tsuboi, Kenta Kobayashi, Mutsuki Amano, Sakura Nakauchi, Takashi Nakano, Kazuto Kobayashi, Kozo Kaibuchi, Shinichi Nakamuta, Akinori Nishi
Publikováno v:
Neuron. 89(3):550-565
Dopamine (DA) type 1 receptor (D1R) signaling in the striatum presumably regulates neuronal excitability and reward-related behaviors through PKA. However, whether and how D1Rs and PKA regulate neuronal excitability and behavior remain largely unknow
Autor:
Tetsuya Takano, Takashi Namba, Chundi Xu, Takashi Watanabe, Shinichi Nakamuta, Yasuhiro Funahashi, Kozo Kaibuchi
Publikováno v:
The Journal of Neuroscience. 35:14517-14532
How extracellular cues direct axon–dendrite polarization in mouse developing neurons is not fully understood. Here, we report that the radial glial cell (RGC)–cortical neuron interaction directs axon formation at the opposite side of the neuron f
Autor:
Kozo Kaibuchi, Takashi Namba, Chundi Xu, Shinichi Nakamuta, Yasuhiro Funahashi, Tetsuya Takano
Publikováno v:
Physiological Reviews. 95:995-1024
Neurons are one of the highly polarized cells in the body. One of the fundamental issues in neuroscience is how neurons establish their polarity; therefore, this issue fascinates many scientists. Cultured neurons are useful tools for analyzing the me
Autor:
Tomonari Hamaguchi, Takashi Watanabe, Mutsuki Amano, Naruki Ishizawa, Takashi Namba, Mengya Wu, Tetsuya Takano, Klaus M. Hahn, Honda Naoki, Kozo Kaibuchi, Chundi Xu, Yoshimitsu Yura, Shinichi Nakamuta
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
A long-standing question in neurodevelopment is how neurons develop a single axon and multiple dendrites from common immature neurites. Long-range inhibitory signaling from the growing axon is hypothesized to prevent outgrowth of other immature neuri
Publikováno v:
Current Opinion in Neurobiology. 27:215-223
Neurons are one of the most polarized cell types in the body. During the past three decades, many researchers have attempted to understand the mechanisms of neuronal polarization using cultured neurons. Although these studies have succeeded in discov