Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Shinichi Kiso"'
Autor:
Tomohide Kurahashi, Yuichi Yoshida, Satoshi Ogura, Mayumi Egawa, Kunimaro Furuta, Hayato Hikita, Takahiro Kodama, Ryotaro Sakamori, Shinichi Kiso, Yoshihiro Kamada, I-Ching Wang, Hidetoshi Eguchi, Eiichi Morii, Yuichiro Doki, Masaki Mori, Vladimir V. Kalinichenko, Tomohide Tatsumi, Tetsuo Takehara
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 425-446 (2020)
Background & Aims: Liver inflammation has been recognized as a hallmark of hepatocarcinogenesis. Although Forkhead Box M1 (FoxM1) is a well-defined oncogenic transcription factor that is overexpressed in hepatocellular carcinoma (HCC), its role in li
Externí odkaz:
https://doaj.org/article/5ba2358818af4cb5928d97ec632e1731
Autor:
Yoshihiro Kamada, Maaya Akita, Yuri Takeda, Shin Yamada, Hideki Fujii, Yoshiyuki Sawai, Yoshinori Doi, Hitomi Asazawa, Kotarosumitomo Nakayama, Kayo Mizutani, Hironobu Fujii, Takayuki Yakushijin, Masanori Miyazaki, Hisao Ezaki, Naoki Hiramatsu, Yuichi Yoshida, Shinichi Kiso, Yasuharu Imai, Norifumi Kawada, Tetsuo Takehara, Eiji Miyoshi
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66328 (2013)
Nonalcoholic fatty liver disease (NAFLD) is a growing medical problem around the world. NAFLD patients with nonalcoholic steatohepatitis (NASH) can develop cirrhosis and hepatocellular carcinoma. The ability to distinguish NASH from simple steatosis
Externí odkaz:
https://doaj.org/article/94493805052345049b4451e8919f156c
Autor:
Mayumi Egawa, Tomohide Kurahashi, Hidetoshi Eguchi, Satoshi Ogura, Yuichi Yoshida, Kunimaro Furuta, Takashi Kizu, Yoshihiro Kamada, Masaki Mori, Mina Hamano, Norihiro Chatani, Shinichi Kiso, Yuichiro Doki, Hayato Hikita, Tetsuo Takehara, Tomohide Tatsumi, Hiroaki Nagano
Publikováno v:
Hepatology Research. 47:1196-1205
AIM Forkhead Box M1 (FoxM1) is a proliferation-specific transcription factor. In this study, we aimed to elucidate the clinicopathological and prognostic values of FoxM1 expression in human hepatocellular carcinoma (HCC) and correlate FoxM1 expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a8f66f420628de94abe0bda9526d0d5
https://doi.org/10.1111/hepr.12854
https://doi.org/10.1111/hepr.12854
Autor:
Kazuhiro Tanabe, Nobuhiro Ookubo, Tadashi Ikegami, Yasushi Matsuzaki, Kenji Ohe, Yusuke Murata, Naoyuki Togawa, Shinichi Kiso, Masayoshi Mori, Akira Honda, Munechika Enjoji, Makoto Nakamuta, Naoki Tanaka, Kazufumi Dohmen
Publikováno v:
Journal of Hepatology. 70:e541-e542
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0470d81bada6144247562200749a65a3
https://doi.org/10.1016/s0618-8278(19)31071-0
https://doi.org/10.1016/s0618-8278(19)31071-0
Autor:
Yoshihiro Kamada, Norihiro Chatani, Shinichi Kiso, Mina Hamano, Takayo Takemura, Hisao Ezaki, Satoshi Ogura, Mayumi Egawa, Keigo Nishida, Kunimaro Furuta, Yoshikazu Nakaoka, Tetsuo Takehara, Yuichi Yoshida, Takashi Kizu
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 308:G613-G624
Grb2-associated binder 1 (Gab1) adaptor protein amplifies signals downstream of a broad range of growth factors/receptor tyrosine kinases. Although these signals are implicated in liver fibrogenesis, the role of Gab1 remains unclear. To elucidate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14c5b32644ea7b0ad933232dfbbadfe
https://doi.org/10.1152/ajpgi.00289.2014
https://doi.org/10.1152/ajpgi.00289.2014
Autor:
Yoshihiro Kamada, Mayumi Egawa, Norihiro Chatani, Satoshi Ogura, Yuichi Yoshida, Shinichi Kiso, Hisao Ezaki, Kunimaro Furuta, Akihiko Shimono, Takashi Kizu, Mina Hamano, Noriyuki Ouchi, Tetsuo Takehara
Publikováno v:
Liver International. 35:2017-2026
Background & Aims Obesity-related adipocytokine dysregulation is known to accelerate liver fibrosis progression. Recently, a natural Wnt5a inhibitor, secreted frizzled-related protein 5 (Sfrp5), was identified as a novel adipocytokine that has reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6564217aa9dd9401e75bcfd2b2b9bc44
https://doi.org/10.1111/liv.12757
https://doi.org/10.1111/liv.12757
Autor:
Mayumi Egawa, Hidetoshi Eguchi, Hayato Hikita, Kunimaro Furuta, Masaki Mori, Yoshihiro Kamada, Shinichi Kiso, Hisakazu Ogita, Tomohide Kurahashi, Satoshi Ogura, Yuichi Yoshida, Tetsuo Takehara, Yuichiro Doki, Tomohide Tatsumi
Publikováno v:
Oncotarget
Dysregulation of cell metabolism is a hallmark of cancer. The mevalonate pathway in lipid metabolism has been implicated as a potential target of cancer therapy for hepatocellular carcinoma (HCC). The role of the Forkhead Box M1 (FoxM1) transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705ce4e743501d7ae8903dd3f571b271
https://pubmed.ncbi.nlm.nih.gov/29765517
https://pubmed.ncbi.nlm.nih.gov/29765517
Autor:
K. Tanabe, Shinichi Kiso, M. Nakamuta, Shusuke Morizono, N. Togawa, Munechika Enjoji, Kenji Ohe, N. Ookubo
Publikováno v:
Journal of Hepatology. 68:S350-S351
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a3ce3fcd3760e1e5f835b56731ad453
https://doi.org/10.1016/s0168-8278(18)30923-1
https://doi.org/10.1016/s0168-8278(18)30923-1
Autor:
Kayo Mizutani, Norifumi Kawada, Yuichi Yoshida, Yoshiyuki Sawai, Maaya Akita, Shinichi Kiso, Eiji Miyoshi, Yoshihiro Kamada, Masanori Miyazaki, Takayuki Yakushijin, Yoshinori Doi, Yasuharu Imai, Tetsuo Takehara, Naoki Hiramatsu, Sachiho Kida, Hideki Fujii, Noriaki Kinoshita, Nobuhiro Maruyama, Hironobu Fujii, Naofumi Uozumi, Hisao Ezaki, Motoya Sato
Publikováno v:
PROTEOMICS - Clinical Applications. 7:648-656
Purpose Mac-2 binding protein (Mac-2bp) is one of the major fucosylated glycoproteins, which we identified with glycol-proteomic analyses. We previously reported that fucosylated glycoproteins are secreted into bile, but scarcely secreted into sera i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b6ca1e13c151973ccd3c57b8295a82
https://doi.org/10.1002/prca.201200137
https://doi.org/10.1002/prca.201200137
Autor:
Yoshihiro Kamada, Mayumi Egawa, Kunimaro Furuta, Mina Hamano, Shinichi Kiso, Norihiro Chatani, Hisao Ezaki, Yuichi Yoshida, Takashi Kizu, Tetsuo Takehara
Publikováno v:
Journal of Gastroenterology
Background and aim Impaired fatty liver regeneration has already been reported in many genetic modification models. However, in diet-induced simple hepatic steatosis, which showed similar phenotype with clinical pathology, whether liver regeneration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94133b5051dd0d9b7436e225204576ee
https://doi.org/10.1007/s00535-013-0780-7
https://doi.org/10.1007/s00535-013-0780-7