Zobrazeno 1 - 10
of 350
pro vyhledávání: '"Shinichi KONDO"'
Autor:
Alessia Salamone, Gaetano Terrone, Rossella Di Sapia, Silvia Balosso, Teresa Ravizza, Luca Beltrame, Ilaria Craparotta, Laura Mannarino, Sara Raimondi Cominesi, Massimo Rizzi, Alberto Pauletti, Sergio Marchini, Luca Porcu, Till S. Zimmer, Eleonora Aronica, Matthew During, Brett Abrahams, Shinichi Kondo, Toshiya Nishi, Annamaria Vezzani
Publikováno v:
Neurobiology of Disease, Vol 173, Iss , Pp 105835- (2022)
Therapies for epilepsy mainly provide symptomatic control of seizures since most of the available drugs do not target disease mechanisms. Moreover, about one-third of patients fail to achieve seizure control. To address the clinical need for disease-
Externí odkaz:
https://doaj.org/article/a8d72f20e7364f5fb631d3c581366d20
Autor:
Shuuichi Miyakawa, Hiroyuki Sakuma, Dnyaneshwar Warude, Satomi Asanuma, Naoto Arimura, Tomoki Yoshihara, Daniel Tavares, Akito Hata, Koh Ida, Yuri Hori, Yuumi Okuzono, Syunsuke Yamamoto, Koichi Iida, Hisao Shimizu, Shinichi Kondo, Shuji Sato
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Progranulin (PGRN) haploinsufficiency associated with loss-of-function mutations in the granulin gene causes frontotemporal dementia (FTD). This suggests that increasing PGRN levels could have promising therapeutic implications for patients carrying
Externí odkaz:
https://doaj.org/article/1bfd1d0933a04c75b1f1c53ea0ed5fe5
Autor:
Michitaka Shichijo, Shinichi Kondo, Mina Ishimori, Shinichi Watanabe, Heidi Helin, Tsugiko Yamasaki, Mary E Stevens, Florian Gantner, Kevin B Bacon
Publikováno v:
Allergology International, Vol 55, Iss 3, Pp 271-278 (2006)
Background: To investigate the functional role of protease activated receptor (PAR) -2 in T lymphocytes, we analyzed TCR-mediated inflammatory cytokine production using PAR-2 deficient (KO) and wild type (WT) mice. Methods: Production of serum IgE an
Externí odkaz:
https://doaj.org/article/39843e3c18dd46c38ca10ccc9dfbf58e
Autor:
Toshiya Nishi, Cameron S. Metcalf, Shinji Fujimoto, Shigeo Hasegawa, Maki Miyamoto, Eiji Sunahara, Sayuri Watanabe, Shinichi Kondo, H. Steve White
Publikováno v:
Epilepsia. 63(6)
The formation of 24S-hydroxycholesterol is a brain-specific mechanism of cholesterol catabolism catalyzed by cholesterol 24-hydroxylase (CYP46A1, also known as CH24H). CH24H has been implicated in various biological mechanisms, whereas pharmacologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5fc7b5260a91d1b998d234df7d07e8
https://pubmed.ncbi.nlm.nih.gov/35316533
https://pubmed.ncbi.nlm.nih.gov/35316533
Autor:
Shinichi Kondo
Publikováno v:
Journal of The Surface Finishing Society of Japan. 71:432-441
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d25721565fcf62bc087ec9ad20c7c78c
https://doi.org/10.4139/sfj.71.432
https://doi.org/10.4139/sfj.71.432
Autor:
Levi Barse, Kazuhiro Yamakawa, Brett S. Abrahams, Manuel Jurado, Toshiya Nishi, Tetsuya Tatsukawa, Jennifer A. Kearney, Tyler T Thaxton, Maki Miyamoto, Nicole A. Hawkins, Matthew J. During, Samantha E Duarte, Shinichi Kondo
Publikováno v:
Epilepsia. 62(11)
Objective Dravet syndrome is a severe developmental and epileptic encephalopathy (DEE) most often caused by de novo pathogenic variants in SCN1A. Individuals with Dravet syndrome rarely achieve seizure control and have significantly elevated risk for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c4b2a2f53c8db23f7d6f0e42f46bab
https://pubmed.ncbi.nlm.nih.gov/34510432
https://pubmed.ncbi.nlm.nih.gov/34510432
Publikováno v:
Fuel. 243:28-33
In this study, for filtration of gasoline particulates, we tested SiC fibers potentially applied for a gasoline particulate filter (GPF). Carbon particles were used as model soot. Focusing on the porosity and the fiber diameter, the filtration effici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daaa13d08ca738595385792039af292a
https://nagoya.repo.nii.ac.jp/records/2001502
https://nagoya.repo.nii.ac.jp/records/2001502
Autor:
Momoko Ohori, Etsurou Watanabe, Tsuyoshi Ishi, Jason Yano, Shigeru Kondo, Shinji Fujimoto, Maki Miyamoto, Masato Yoshikawa, Toshiya Nishi, Takanobu Kuroita, Sayuri Watanabe, Haruhi Kamisaki Ando, Eiji Sunahara, William Farnaby, Shigeo Hasegawa, Shinichi Kondo, Tatsuki Koike, Matthew J. During
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Cholesterol 24-hydroxylase (CH24H) is a brain-specific enzyme that converts cholesterol into 24S-hydroxycholesterol, the primary mechanism of cholesterol catabolism in the brain. The therapeutic potential of CH24H activation has been extensively inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca7856127e7b3d451e213fd65a9a474
https://doi.org/10.1038/s41598-020-74036-6
https://doi.org/10.1038/s41598-020-74036-6
Autor:
Shuji Sato, Yuumi Okuzono, Tomoki Yoshihara, Akito Hata, Hiroyuki Sakuma, Shuuichi Miyakawa, Koh Ida, Koichi Iida, Naoto Arimura, Dnyaneshwar Warude, Syunsuke Yamamoto, Daniel Tavares, Shinichi Kondo, Hisao Shimizu, Yuri Hori, Satomi Asanuma
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 14 (2020)
Frontiers in Neuroscience, Vol 14 (2020)
Progranulin (PGRN) haploinsufficiency associated with loss-of-function mutations in the granulin gene causes frontotemporal dementia (FTD). This suggests that increasing PGRN levels could have promising therapeutic implications for patients carrying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ce6d69f0613c05db94c688983ae4f3
https://pubmed.ncbi.nlm.nih.gov/33384578
https://pubmed.ncbi.nlm.nih.gov/33384578
Autor:
Shinichi Inage, Shinichi Kondo
Publikováno v:
IEEJ Transactions on Power and Energy. 138:541-548
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30276f87541cd6da6f891b1d4c56f037
https://doi.org/10.1541/ieejpes.138.541
https://doi.org/10.1541/ieejpes.138.541