Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Shinichi KAKUMU"'
Autor:
Naoki Hotta, Minoru Ayada, Akihiko Okumura, Tetsuya Ishikawa, Ken Sato, Tomohiko Oohashi, Yasutaka Hijikata, Shinichi Kakumu
Publikováno v:
Case Reports in Gastroenterology, Vol 3, Iss 2, Pp 175-181 (2009)
A 41-year-old Japanese man had received successful interferon (IFN) therapy against chronic hepatitis C in 1994. Since then, serum hepatitis C virus (HCV) RNA had been negative, and aminotransferase levels had been continuously normal. He had abstain
Externí odkaz:
https://doaj.org/article/e10543d25e7a4d63b533bf4e0bb87105
Autor:
Tetsuya Ishikawa, Shinichi Kakumu, Ken Sato, Haruhisa Nakao, Tomohiko Ohashi, Akihiko Okumura, Jun-Ichi Tanabe, Minoru Ayada, Hiroyasu Ito, Teiji Kuzuya, Naoki Hotta, Masashi Yoneda
Publikováno v:
Hepatology Research. 39:510-519
Aim Human hepatocytes are known to express an array of inflammatory cytokines and chemokines. In this study, we examined the potential roles of hepatocytes in regulating immune responses in the liver, by assessing the induction of Th1- or Th2-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020f241325fd69d883407910e8cde956
https://doi.org/10.1111/j.1872-034x.2008.00482.x
https://doi.org/10.1111/j.1872-034x.2008.00482.x
Autor:
Akihiko Okumura, Minoru Ayada, Tetsuya Ishikawa, Shinichi Kakumu, Ken Sato, Yasutaka Hijikata, Naoki Hotta, Tomohiko Oohashi
Publikováno v:
Case Reports in Gastroenterology
Case Reports in Gastroenterology, Vol 3, Iss 2, Pp 175-181 (2009)
Case Reports in Gastroenterology, Vol 3, Iss 2, Pp 175-181 (2009)
A 41-year-old Japanese man had received successful interferon (IFN) therapy against chronic hepatitis C in 1994. Since then, serum hepatitis C virus (HCV) RNA had been negative, and aminotransferase levels had been continuously normal. He had abstain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ae69defcc02c4c3ed8a6180b9c0c41
https://doi.org/10.1159/000225244
https://doi.org/10.1159/000225244
Autor:
Akinori Hirose, Shinichi Kakumu, Naoki Hotta, Akihiko Okumura, Minoru Ayada, Kazuo Masuko, Tetsuya Ishikawa
Publikováno v:
Kanzo. 50:139-144
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a1dac252ffd0cdba8210b940db4f8e8
https://doi.org/10.2957/kanzo.50.139
https://doi.org/10.2957/kanzo.50.139
Publikováno v:
Liver. 9:14-19
Our study was undertaken to determine whether human recombinant interferon alpha(rIFN alpha), gamma(rIFN gamma), and tumor necrosis factor alpha(rTNF alpha) exert an effect on the HLA-A, B, C expression of human liver cell lines. The HLA-A, B, C expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b042737c43fd5353c620bd33225191df
https://doi.org/10.1111/j.1600-0676.1989.tb00372.x
https://doi.org/10.1111/j.1600-0676.1989.tb00372.x
Publikováno v:
Journal of Gastroenterology. 43:866-874
DNA microarray technology has enabled genomewide analysis of gene transcript levels, yielding insight into the molecular nature of liver disease. We compared gene expression of liver biopsy specimens in 16 patients with different stages of chronic he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5807d3b39e7535942e629ebadc666f2
https://doi.org/10.1007/s00535-008-2237-y
https://doi.org/10.1007/s00535-008-2237-y
Publikováno v:
Hepatology Research. 38:673-682
AIM DNA microarray technology has enabled genome-wide analysis of gene transcript levels, which has yielded insight into the molecular nature of hepatitis C virus infection. However, little insight into the molecular nature of the early to advanced s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09add0e746a6fb0a1f96f893c186230c
https://doi.org/10.1111/j.1872-034x.2008.00328.x
https://doi.org/10.1111/j.1872-034x.2008.00328.x
Autor:
Michio Kato, Harumasa Yoshihara, Norio Hayashi, Tsugiko Oze, Nao Kurashige, Akinori Kasahara, Sumio Kawata, Shinichi Kakumu, Takeshi Okanoue, Tetsuo Takehara, Hirohito Tsubouchi, Masahide Oshita, Hiromitsu Kumada, Shinji Tamura, Naoki Hiramatsu, Kazuhiro Katayama, Yasuharu Imai
Publikováno v:
Hepatology Research. 38:52-59
Aim: Ribavirin, used to treat chronic hepatitis C, can induce hemolytic anemia, forcing the discontinuance of treatment. To establish a predictive measure to help circumvent this, we evaluated the relationship of hemoglobin (Hb) decline with the disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619ccae0886b960440ed01ccc0fb1e10
https://doi.org/10.1111/j.1872-034x.2007.00205.x
https://doi.org/10.1111/j.1872-034x.2007.00205.x
Autor:
Shinichi Kakumu, Tetsuya Ishikawa
Publikováno v:
Hepatology Research. 37:S347-S350
Current therapeutic approaches to control chronic hepatitis B (CH-B), such as administrations of interferon or nucleoside analogs, are still unsatisfactory. Vaccination with conventional hepatitis B (HB) vaccine is another therapeutic approach with l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a45ad141985c2460de0d42ca79a2ac
https://doi.org/10.1111/j.1872-034x.2007.00231.x
https://doi.org/10.1111/j.1872-034x.2007.00231.x
Autor:
Tetsuya Ishikawa, Shinichi Kakumu
Publikováno v:
Hepatology Research. 37:S62-S66
BACKGROUND AND AIM Lamivudine (LAM) has problems of breakthrough hepatitis (BTH) and post-treatment relapse despite its significant effect for suppressing hepatitis B virus (HBV) replication. In order to find solutions for the problems, the efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec4303e4529a5fe946c965e1c85b113
https://doi.org/10.1111/j.1872-034x.2007.00107.x
https://doi.org/10.1111/j.1872-034x.2007.00107.x