Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Shinichi, Kume"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Methionine adenosyltransferase (MAT) is involved in folate-mediated one-carbon metabolism, which is essential for preimplantation embryos in terms of both short-term periconceptional development and long-term phenotypic programming beyond th
Externí odkaz:
https://doaj.org/article/bc8da6bb4b7742a0af905ecd4e44e8e0
Autor:
Chihiro Okuma, Takeshi Ohta, Hironobu Tadaki, Tatsuya Ishigure, Shohei Sakata, Hideyuki Taniuchi, Ryuhei Sano, Hiromi Hamada, Shinichi Kume, Jun Nishiu, Makoto Kakutani
Publikováno v:
Journal of Pharmacological Sciences, Vol 128, Iss 3, Pp 150-157 (2015)
Aim: Monoacyglycerol acyltransferases (MGATs) are known to play important roles in intestinal TG absorption. In contrast, the role of MGATs in the liver is still unclear. We investigated the effects of JTP-103237, a novel MGAT inhibitor, on hepatic M
Externí odkaz:
https://doaj.org/article/4f84e16fc93843638e297033bf9858ca
Autor:
Chihiro Okuma, Takeshi Ohta, Makoto Ito, Hironobu Tadaki, Tomohiro Oda, Shinichi Kume, Jun Nishiu, Makoto Kakutani
Publikováno v:
Journal of Pharmacological Sciences, Vol 130, Iss 2, Pp 136-138 (2016)
Some nutrients, such as carbohydrate, fat and protein, are known to stimulate satiety. However, the effect of sn-2-monoacylglycerol (2-MG), one of the digestive products of triglycerides, on food intake is still unclear. In the present study, the eff
Externí odkaz:
https://doaj.org/article/75e71d1997c94870b15a717a96be6fdf
Autor:
Tsukasa Shimizu, Akito Yamasaki, Hideo Inoue, Takuma Ito, Shinichi Kume, Masao Nagai, Pongsathorn Raksincharoensak, Shintaro Inoue, Masahiro Imai, Yuichi Saito, Ryoma Yoshimi
Publikováno v:
Transportation Research Part F: Traffic Psychology and Behaviour. 77:221-235
It is imperative to enhance the safety of elderly individuals on the roads to ensure the quality of their daily life. Near-miss incidents or accidents at blind intersections often result from a conflict between the behaviors of the driver and of othe
Autor:
Takeshi Ohta, Shuntaro Ikeda, Kai Egashira, Miki Sugimoto, Naojiro Minami, Shinichi Kume, Hiroki Ishitani
Publikováno v:
J Assist Reprod Genet
PURPOSE: Reduction in methylenetetrahydrofolate reductase (MTHFR) activity due to genetic variations in the MTHFR gene has been controversially implicated in subfertility in human in vitro fertilization. However, there is no direct gene-knockdown stu
Publikováno v:
THE PROCEEDINGS OF THE 4TH EPI INTERNATIONAL CONFERENCE ON SCIENCE AND ENGINEERING (EICSE) 2020.
Autor:
Shinichi Kume, Ryosuke Matsumi, Akito Yamasaki, Xun Shen, Yuichi Saito, Masao Nagai, Toshiki Kinoshita, Takuma Ito, Ryoma Yoshimi, Hideo Inoue, Tsukasa Shimizu, Pongsathorn Raksincharoensak, Shintaro Inoue
Publikováno v:
IEEE Transactions on Intelligent Transportation Systems.
Elderly drivers often tend to disobey stop signs, and the number of vehicle accidents associated with this is increasing. The problem we address in this work is that of failure (or inability) of elderly drivers to identify potential conflicts with ot
Autor:
T. Yamada, M. Muramatsu, E Riya, Takeshi Ohta, Yasufumi Toriniwa, Katsuhiro Miyajima, Yukihito Ishii, Shinichi Kume, Susumu Takekoshi, T Matsui, Kanae Kitatani, S Ohshida
Publikováno v:
Physiological Research. :601-612
Spontaneously Diabetic Torii (SDT) fatty rats, a new obese diabetic model, reportedly presented with features of non-alcoholic steatohepatitis (NASH) after 32 weeks of age. We tried to accelerate the onset of NASH in SDT fatty rats using dietary chol
Autor:
Takeshi Ohta, Kazuo Sasagawa, Yukihito Ishii, Katsuya Sakimura, Shinichi Kume, Tatsuya Maekawa
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 45:927-933
Depression is one of the most common psychiatric diseases and is commonly comorbid with type 1 or 2 diabetes mellitus (DM). However, the pathophysiology underlying the depressive state in DM remains poorly understood. Animal models are useful tools t
Autor:
Yoshinobu Nakatsuji, Taisuke Yamaji, Maho Ishida, Kenichi Yoshitani, Yuji Sugie, Masahiko Fujita, Shuntaro Ikeda, Shinichi Kume, Atsutoshi Obata, Yoshitaka Nishijima, Yoshikazu Aoki
Publikováno v:
Animal Science Journal. 89:1102-1106
Data from 26 Japanese Black cows were collected to clarify the effects of supplemental β-carotene on colostral immunoglobulin (Ig) and plasma β-carotene and Ig in the cows. Cows were assigned to control or β-carotene groups from 21 days before the