Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Shingo Yamada"'
Autor:
Kiyohito Hayashi, Daisuke Koyama, Yoichi Hamazaki, Takamichi Kamiyama, Shingo Yamada, Miki Furukawa, Yoshinori Tanino, Yoko Shibata, Takayuki Ikezoe
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-8 (2024)
Abstract Background The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has had a profound global impact, with millions of confirmed cases and deaths worldwide. While most cases ar
Externí odkaz:
https://doaj.org/article/f135483a01e54790842d1aa30d0fdaa2
Autor:
Kenshin Shimono, Takashi Ito, Chinatsu Kamikokuryo, Shuhei Niiyama, Shingo Yamada, Hirokazu Onishi, Hideaki Yoshihara, Ikuro Maruyama, Yasuyuki Kakihana
Publikováno v:
Thrombosis Journal, Vol 21, Iss 1, Pp 1-9 (2023)
Abstract Background Upon cellular injury, damage-associated molecular patterns (DAMPs) are released into the extracellular space and evoke proinflammatory and prothrombotic responses in animal models of sterile inflammation. However, in clinical sett
Externí odkaz:
https://doaj.org/article/143e0f6f3bf446d59c4cf6e14e30df40
Autor:
Toshihiko Nakamura, Atsushi Yoshida, Daisuke Hatanaka, Michiko Kusakari, Hidehiro Takahashi, Shinji Katsuragi, Shingo Yamada, Takashi Kamohara
Publikováno v:
Practical Laboratory Medicine, Vol 36, Iss , Pp e00327- (2023)
Background: High mobility group box 1 (HMGB-1) has been extensively studied in adults and to a certain extent in neonates as well. Clinical examination of neonates, especially unwell neonates soon after birth, should be minimally invasive. Objective:
Externí odkaz:
https://doaj.org/article/f194c49229644f20a4559a99f738792d
Autor:
Hirotaka Mori, Yuki Kataoka, Kayo Harada-Shirado, Noriaki Kawano, Mineji Hayakawa, Yoshinobu Seki, Toshimasa Uchiyama, Kazuma Yamakawa, Hiroyasu Ishikura, Yuhei Irie, Kenji Nishio, Noritaka Yada, Kohji Okamoto, Shingo Yamada, Takayuki Ikezoe
Publikováno v:
Thrombosis Journal, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background We compared the prognostic value of serum high mobility group box 1 protein (HMGB1) and histone H3 levels with the International Society on Thrombosis and Haemostasis (ISTH) disseminated intravascular coagulation (DIC) scores for
Externí odkaz:
https://doaj.org/article/6b1d6f281e874a68a3dc59c41bac4fb0
Autor:
Munekazu Yamakuchi, Masashi Okawa, Kazunori Takenouchi, Aryal Bibek, Shingo Yamada, Keiichi Inoue, Kazuhiko Higurashi, Akito Tabaru, Kiyonori Tanoue, Yoko Oyama, Sadayuki Higashi, Chieko Fujisaki, Hideaki Kanda, Hiroto Terasaki, Taiji Sakamoto, Yoshiharu Soga, Teruto Hashiguchi
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284131 (2023)
Vascular endothelial growth factor A (VEGF-A) plays pivotal roles in regulating tumor angiogenesis as well as physiological vascular function. The major VEGF-A isoforms, VEGF-A121 and VEGF-A165, in serum, plasma, and platelets have not been exactly e
Externí odkaz:
https://doaj.org/article/e144ed2a35e744a59cd7c9a05b0ea465
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-8 (2021)
Abstract Background During sepsis or sterile tissue injury, the nuclear protein high mobility group box 1 (HMGB1) can be released to the extracellular space and ultimately into systemic circulation, where it mediates systemic inflammation and remote
Externí odkaz:
https://doaj.org/article/06a6f482f8fb4460b4d149a4f587ae52
Autor:
Hikari Tanaka, Hidenori Homma, Kyota Fujita, Kanoh Kondo, Shingo Yamada, Xiaocen Jin, Masaaki Waragai, Gaku Ohtomo, Atsushi Iwata, Kazuhiko Tagawa, Naoki Atsuta, Masahisa Katsuno, Naoki Tomita, Katsutoshi Furukawa, Yuko Saito, Takashi Saito, Ayaka Ichise, Shinsuke Shibata, Hiroyuki Arai, Takaomi Saido, Marius Sudol, Shin-ichi Muramatsu, Hideyuki Okano, Elliott J. Mufson, Gen Sobue, Shigeo Murayama, Hitoshi Okazawa
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-22 (2020)
The precise mechanisms of neuronal cell death in neurodegeneration are not fully understood. Here the authors show that YAP-mediated neuronal necrosis is increased in pre-symptomatic stages of Alzheimer’s disease and intervention to the necrosis re
Externí odkaz:
https://doaj.org/article/f3578dfd2ff148919a9dde2c540ddafd
Autor:
Takafumi Takase, Mizuho Nagao, Rei Kanai, Takahiro Nishida, Tomoyuki Arima, Fumiko Iwai, Shingo Yamada, Makiko Nakamoto, Masahiro Hirayama, Takao Fujisawa
Publikováno v:
Environmental Health and Preventive Medicine, Vol 28, Pp 6-6 (2023)
Background: Recent studies indicate that the timing of introduction of potentially allergenic food is crucial for the development of food allergy in children. This cross-sectional study aimed to clarify the reality of allergen food intake in a genera
Externí odkaz:
https://doaj.org/article/5111962cf1314e9ba7894b981da77d8b
Autor:
Takashi Ito, Takaaki Totoki, Yayoi Yokoyama, Tomotsugu Yasuda, Hiroaki Furubeppu, Shingo Yamada, Ikuro Maruyama, Yasuyuki Kakihana
Publikováno v:
Journal of Intensive Care, Vol 7, Iss 1, Pp 1-7 (2019)
Abstract Background Recent studies have suggested that anticoagulant therapy does not confer a survival benefit overall in sepsis, but might be beneficial in sepsis-associated disseminated intravascular coagulation (DIC). In particular, those with hi
Externí odkaz:
https://doaj.org/article/555b3bbba69d4ed781362a6bd196d2cf
Autor:
Kosaku Hatanaka, Takashi Ito, Yutaro Madokoro, Chinatsu Kamikokuryo, Shuhei Niiyama, Shingo Yamada, Ikuro Maruyama, Yasuyuki Kakihana
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host responses to infection. Recent studies have suggested that endotheliopathy may be the common basis for multiple organ failure in sepsis. Under septic cond
Externí odkaz:
https://doaj.org/article/19e0edb065b444b4be541b99414f1dc2