Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shingo Sekine"'
Autor:
Akiko Mitani, Hideo Matsumoto, Noboru Otsuka, Miyuki Hori, Shinsuke Kaku, Yoshihisa Toda, Masanori Sugimoto, Shingo Sekine, Takahiro Ichihara
Publikováno v:
Drug Development Research
Preclinical Research The aim of this study was to evaluate the efficacy of multiple applications of S(+)‐flurbiprofen plaster (SFPP), a novel Nonsteroidal anti‐inflammatory drug (NSAID) patch, for the alleviation of inflammatory pain and edema in
Autor:
Takuya Hirose, Nobuko Futaki, Takahiro Ichihara, Miyuki Hori, Yoshihisa Toda, Akiko Mitani, Shingo Sekine, Hideo Matsumoto, Shinsuke Kaku, Masanori Sugimoto, Hiromi Endo, Noboru Otsuka
Publikováno v:
Drug Development Research
Preclinical Research This article describes the properties of a novel topical NSAID (Nonsteroidal anti‐inflammatory drug) patch, SFPP (S(+)‐flurbiprofen plaster), containing the potent cyclooxygenase (COX) inhibitor, S(+)‐flurbiprofen (SFP). Th
Autor:
Takahiro Ichihara, Hiromi Endo, Shingo Sekine, Yoshihisa Toda, Masanori Sugimoto, Shinsuke Kaku, Takuya Hirose, Akiko Mitani, Hideo Matsumoto, Noboru Otsuka, Miyuki Hori
Publikováno v:
Osteoarthritis and Cartilage. 24:S504-S505
Publikováno v:
Journal of Biochemistry. 122:622-626
Recently, we developed a simple method for detecting a secretory signal sequence encoded by a cDNA fragment. In this study, we used this method to select cDNA clones encoding secretory proteins from a human full-length cDNA library. Full-sequencing a
Autor:
Nobuko Futaki, Shingo Sekine, Hiromitsu Yoshimura, Akiko Mitani, Hisashi Adachi, Yoshikatsu Uematsu, Noriaki Shimizu
Publikováno v:
Protein expression and purification. 80(1)
We report the expression of a high level of human cyclooxygenase-1 (hCOX-1) in mammalian cells using a novel gene amplification method known as the IR/MAR gene amplification system. IR/MAR-plasmids contain a mammalian replication initiation region (I
Publikováno v:
Journal of Biochemistry. 117:359-361
We have isolated two kinds of cDNA clones encoding glyoxalase I from a human fibrosarcoma HT-1080 cDNA library. One of them is identical to the glyoxalase I cDNA isolated by us, and the other encodes a protein in which alanine at position 111 of the
Publikováno v:
Journal of biochemistry. 124(1)
During large-scale in vitro translation analysis of a human full-length cDNA bank, we found a clone producing a remarkably smaller translation product than that expected from the open reading frame. The cDNA encodes a polyubiquitin, UbC, composed of
Autor:
Yoshihiro Takemoto, Seishi Kato, Shigeyuki Arai, Satoshi Tsukada, Jouji Inazawa, Shoji Hashimoto, Shingo Sekine, Toshio Kunikata, Tadamitsu Kishimoto, Masato Matsushita, Masashi Kurimoto, Yoshihiro Baba, Tomoki Yamadori
Publikováno v:
Biochemical and biophysical research communications. 245(2)
Protein interaction cloning method was used to identify a novel molecule, Sab, which binds to the SH3 domain of Bruton's tyrosine kinase (Btk), the deficient cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia and murine X-linked immunod
Autor:
Y. Umezawa, Su-Wan Oh, N. Abe, Seishi Kato, M. Yokoyama-Kobayashi, Nam-Soon Kim, Shingo Sekine, T. Aoki
Publikováno v:
Gene. 150(2)
We aimed to construct a full-length cDNA bank from an entire set of human genes and to analyze the function of a protein encoded by each cDNA. To achieve this purpose, a multifunctional phagemid shuttle vector, pKA1, was constructed for preparing a h
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