Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Shingo Nakajima"'
Autor:
Shingo Nakajima, Geneviève Demers, Arturo Israel Machuca-Parra, Zahra Dashtehei Pour, Diane Bairamian, Khalil Bouyakdan, Alexandre Fisette, Anita Kabahizi, Josephine Robb, Demetra Rodaros, Cyril Laurent, Guillaume Ferreira, Nathalie Arbour, Thierry Alquier, Stephanie Fulton
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract G protein-coupled receptor 120 (GPR120, Ffar4) is a sensor for long-chain fatty acids including omega-3 polyunsaturated fatty acids (n-3 PUFAs) known for beneficial effects on inflammation, metabolism, and mood. GPR120 mediates the anti-infl
Externí odkaz:
https://doaj.org/article/f87ce8b1f2204c9eb17e5b7be56e1bd7
Publikováno v:
Frontiers in Neuroanatomy, Vol 14 (2021)
Repressor element-1 silencing transcription factor (REST) is highly expressed in the dorsal raphe where serotonin (5-hydroxytryptamine, 5-HT) neurons are located. REST works as a transcription factor for the 5-HT receptor and tryptophan hydroxylase t
Externí odkaz:
https://doaj.org/article/973c3d225af5422aac6aa729dcabdb76
Autor:
Shingo Nakajima, Hiroshi Kunugi
Publikováno v:
Heliyon, Vol 6, Iss 5, Pp e03892- (2020)
Previous studies have suggested the potential efficacy of middle chain fatty acids (MCFAs) in the treatment of mood disorders and cognitive dysfunction. MCFAs are metabolized to ketone bodies in astrocytes; however, their effects on neuronal developm
Externí odkaz:
https://doaj.org/article/cc3bf9d05d36488b93a6e2ec17a0415b
Autor:
Yuki Shibaike, Mari Gotoh, Chinatsu Ogawa, Shingo Nakajima, Keisuke Yoshikawa, Tetsuyuki Kobayashi, Kimiko Murakami-Murofushi
Publikováno v:
Biochemistry and Biophysics Reports, Vol 19, Iss , Pp - (2019)
Cyclic phosphatidic acid (cPA) is a naturally occurring phospholipid mediator that contains a unique cyclic phosphate ring at the sn-2 and sn-3 positions of its glycerol backbone. Using mouse models for multiple sclerosis (cuprizone-induced demyelina
Externí odkaz:
https://doaj.org/article/f1f4e810053543f7a51c8bd6d9690d37
Autor:
Haruki Odaka, Tadahiro Numakawa, Naoki Adachi, Yoshiko Ooshima, Shingo Nakajima, Yusuke Katanuma, Takafumi Inoue, Hiroshi Kunugi
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99271 (2014)
Several lines of evidence demonstrate that oxidative stress is involved in the pathogenesis of neurodegenerative diseases, including Parkinson's disease. Potent antioxidants may therefore be effective in the treatment of such diseases. Cabergoline, a
Externí odkaz:
https://doaj.org/article/5845c357145744ae91742fe6b4df9680
Autor:
Hitomi Matsuno, Shoko Tsuchimine, Kazunori O’Hashi, Kazuhisa Sakai, Kotaro Hattori, Shinsuke Hidese, Shingo Nakajima, Shuichi Chiba, Aya Yoshimura, Noriko Fukuzato, Mayumi Kando, Megumi Tatsumi, Shintaro Ogawa, Noritaka Ichinohe, Hiroshi Kunugi, Kazuhiro Sohya
Publikováno v:
Molecular Psychiatry. 27:3822-3832
Several lines of evidence suggest that stress induces the neurovascular dysfunction associated with increased blood-brain barrier (BBB) permeability, which could be an important pathology linking stress and psychiatric disorders, including major depr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e740e3389394288a9b86bd4831ff6d42
https://doi.org/10.1038/s41380-022-01618-3
https://doi.org/10.1038/s41380-022-01618-3
Publikováno v:
Trends in Endocrinology & Metabolism. 33:18-35
The incidence of depression and anxiety is amplified by obesity. Mounting evidence reveals that the psychiatric consequences of obesity stem from poor diet, inactivity, and visceral adipose accumulation. Resulting metabolic and vascular dysfunction,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1fc4695b681ffaaa31d84d9ca06776a
https://doi.org/10.1016/j.tem.2021.10.005
https://doi.org/10.1016/j.tem.2021.10.005
Publikováno v:
IEICE Communications Express. 10:271-276
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5f64a23c320517dedb3dcaa4e9243ac
https://doi.org/10.1587/comex.2021xbl0017
https://doi.org/10.1587/comex.2021xbl0017
Publikováno v:
International Journal of Obesity. 44:727-738
Obesity is considered to be a risk factor for neurodegenerative- and psychiatric- diseases including Alzheimer’s disease, schizophrenia, and depression. A high-lard diet is widely used to induce obesity in model animal experiments, which also leads
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3d928787580e9299b0e5608d4b21a8
https://doi.org/10.1038/s41366-019-0468-z
https://doi.org/10.1038/s41366-019-0468-z
Publikováno v:
Current Opinion in Endocrine and Metabolic Research. 24:100338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63aae1a33399ca9bd7e3f92660abf207
https://doi.org/10.1016/j.coemr.2022.100338
https://doi.org/10.1016/j.coemr.2022.100338