Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Shingo Nagaya"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10648 (2022)
Ceramide levels controlled by the sphingomyelin (SM) cycle have essential roles in cancer cell fate through the regulation of cell proliferation, death, metastasis, and drug resistance. Recent studies suggest that exosomes confer cancer malignancy. H
Externí odkaz:
https://doaj.org/article/ba1ac3b56ead4df88197a77589183b54
Autor:
Kenta Arai, Ken Watanabe, Makoto Taniguchi, Kazuhiko Hayashi, Yoshibumi Ueda, Koichi Fukase, Toshiro Okazaki, Shingo Nagaya, Chieko Hashizume, Kazuya Kabayama, Lusi Oka Wardhani, Michiko Matsushita
Publikováno v:
The FASEB Journal. 34:3838-3854
The tumor microenvironment (TME) formation involving host cells and cancer cells through cell adhesion molecules (CAMs) is essential for the multiple steps of cancer metastasis and growth. Sphingomyelin synthase 2 (SMS2) is involved in inflammatory d
Autor:
Makoto Taniguchi, Yoshibumi Ueda, Yoritaka Fujii, Toshiro Okazaki, Chieko Hashizume, Ken Watanabe, Takeo Kosaka, Hiroyuki Takeya, Shingo Nagaya
Publikováno v:
Blood advances. 5(20)
Sphingomyelin synthase 1 (SMS1) contributes to the generation of membrane sphingomyelin (SM) and affects SM-mediated physiological functions. Here, we describe the hematologic phenotypes, such as reduced circulating platelets and dysfunctional hemost
Publikováno v:
Plant Biotechnology. 32:317-321
Autor:
Yoshimi Oshima, Shingo Nagaya, Ko Kato, Masaru Ohme-Takagi, Tsuyoshi Nakagawa, Nobutaka Mitsuda, Masaru Nakata
Publikováno v:
Plant Biotechnology. 28:201-210
Chimeric repressor gene-silencing technology (CRES-T) is a powerful tool that has recently been developed for the functional analysis of plant transcription factors and for the genetic manipulation of plant traits. For CRES-T, a transcription factor
Publikováno v:
Plant Biotechnology. 28:493-496
High expression of transgene is one of the key requirements for the successful establishment of transgenic plants to produce a lot of proteins or metabolites. Although the cauliflower mosaic virus 35S (CaMV35S) promoter and the nopaline synthase (NOS
Publikováno v:
Plant Biotechnology. 24:383-392
Specifically accessible chromatin sites, detected as DNase I hypersensitive sites (DNase I HSs), have been found at promoters of most genes in yeast, human as well as in Arabidopsis chromatin. The DNase I HSs are constitutively present at promoters o
Publikováno v:
Plant Biotechnology. 23:451-457
Variable levels of transgene expression are frequently observed among independent transgenic plants. Although different chromatin condensation states surrounding randomly integrated transgenes have previously been thought to be one of the causes for
Autor:
Rie Horie, Yuka Ninomiya, Shingo Nagaya, Atsuhiko Shinmyo, Masami Sekine, Kazuya Yoshida, Ko Kato
Publikováno v:
Plant and Cell Physiology. 46:438-444
The high variability of transgene expression is frequently observed in independent transgenic lines. Variability of transgene expression has been attributed to several factors, including differences in chromosome position, repeat sequences and copy n
Publikováno v:
Japan Agricultural Research Quarterly: JARQ. 39:269-274
We investigated the usefulness of the promoter of a gene for tobacco elongation factor 1α protein (EF1 α) for transgene expression in the chrysanthemum (Chrysanthemum morifolium Ramat.). The EF1 α promoter was fused to the β-glucuronidase gene (g